The Indianapolis Colts and Jacksonville Jaguars play on Sunday, Oct. 6, at EverBank Stadium in a game on the NFL Week 5 schedule .
Which team will win the NFL Week 5 game?
Check out these NFL Week 5 picks and NFL Week 5 predictions for the game, which can be seen at 10 a.m. MST on CBS ( stream with free trial from FUBO ).
The Jaguars are a 2.5-point favorite over the Colts in NFL Week 5 odds for the game, courtesy of BetMGM Sportsbook .
Jacksonville is -145 on the moneyline, while Indianapolis is +120.
The over/under (point total) is set at 46 points.
NFL Week 5 picks: Buccaneers vs Falcons | Jets vs Vikings | Panthers vs Bears | Ravens vs Bengals | Bills vs Texans | Colts vs Jaguars | Dolphins vs Patriots | Browns vs Commanders | Raiders vs Broncos | Cardinals vs 49ers | Packers vs Rams | Giants vs Seahawks | Cowboys vs Steelers | Saints vs Chiefs | The Arizona Republic's predictions
Watch Colts at Jaguars live with FUBO (free trial)
Jeremy Cluff writes: "The Jaguars are favored at home in this game. We think they'll win a game at some point, it might as well come in Week 5."
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Bookies.com : Bet the Colts with the points vs Jaguars
Bill Speros writes: "The Mac Jones watch continues. As does the Doug Pederson watch."
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The site's formula predicts that the Colts will win the NFL Week 5 game against the Jaguars.
NFL Week 5 schedule: Television channels, how to watch, stream games
ESPN : Colts have a 50.4% chance to beat Jaguars on Sunday
The site gives the Jaguars a 49.2% shot at winning the NFL Week 5 game, with the remaining percentage accounting for a tie.
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Dimers : Jaguars 25, Colts 23
It writes: "After extensive simulations, our model gives the Colts a win probability of 41%, while the Jaguars have a win probability of 59%."
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com . Follow him on X, formerly Twitter @Jeremy_Cluff.
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This article originally appeared on Arizona Republic: Indianapolis Colts vs Jacksonville Jaguars picks, predictions: Who wins NFL Week 5 game?
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