The NFL Week 6 schedule kicks off with a Thursday Night Football game between the San Francisco 49ers and Seattle Seahawks at Lumen Field.
Here's what you need to know before the NFL Week 6 Thursday Night Football matchup, including time, TV channel , streaming information, announcers , odds and a prediction for the game.
The 49ers are coming off a 24-23 loss to the Arizona Cardinals in their NFL Week 5 game.
The Seahawks lost to the New York Giants, 29-20.
San Francisco enters the game with a 2-3 record. Seattle is 3-2 on the season. These teams are NFC West division rivals.
NFL Week 6 picks: 49ers vs Seahawks | Jaguars vs Bears | Commanders vs Ravens | Cardinals vs Packers | Texans vs Patriots | Buccaneers vs Saints | Browns vs Eagles | Colts vs Titans | Chargers vs Broncos | Steelers vs Raiders | Falcons vs Panthers | Lions vs Cowboys | Bengals vs Giants | Bills vs Jets | The Arizona Republic's predictions
Watch 49ers at Seahawks live with Amazon Prime
What time is Thursday Night Football?
The 49ers vs Seahawks game is scheduled to begin at 5:15 p.m. MST, 8:15 p.m. ET.
What channel is tonight’s NFL game on? How to watch 49ers vs Seahawks NFL game today
What channel is Thursday Night Football on?
Thursday Night Football's game between the 49ers and Seahawks is not on TV and is only available through streaming .
NFL Week 6 predictions: ESPN matchup predictor's picks, win probabilities for this week
How can I stream Thursday Night Football?
The 49ers at Seahawks Thursday Night Football game will stream exclusively on Amazon Prime Video .
NFL Week 6 schedule: Television channels, how to watch, stream games this week
Who are the announcers for Thursday Night Football?
Al Michaels will have the play-by-play call for the 49ers-Seahawks game, with Kirk Herbstreit as the analyst.
NFL Week 6 announcers: Television broadcasters, announcing crews for NFL Week 6 schedule
Who is the favorite in Thursday Night football odds?
The 49ers are a 3.5-point favorite over the Seahawks in NFL Week 6 odds for the game, courtesy of BetMGM Sportsbook .
San Francisco is -185 on the moneyline, while Seattle is +150.
The over/under (point total) is set at 49 points.
NFL Week 6 odds: Point spreads, moneylines, over/unders for betting on games this week
Who will win on Thursday Night Football?
The Arizona Republic is predicting a 24-21 win for the 49ers over the Seahawks in the Thursday Night Football showdown.
Other sites' NFL Week 6 picks and NFL Week 6 predictions favor San Francisco over Seattle in this week's Thursday Night Football game, the first game on the NFL Week 6 schedule.
NFL Week 6 picks, predictions: Will 49ers, Bucs, Eagles, Bengals, Bills win crucial games?
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This article originally appeared on Arizona Republic: NFL Thursday schedule, TV: How to watch San Francisco 49ers vs Seattle Seahawks game today
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