Mark Cuban says he doesn't plan to run for office when he can make game-changing moves without being president

• Mark Cuban says he doesn't plan to enter politics.
• "No, hell no," Cuban said when Wired's Lauren Goode asked him about it.
• "I can do more from the private sector," Cuban told Goode.

Billionaire investor Mark Cuban says he isn't interested in running for office.

"No, hell no," Cuban told Wired's Lauren Goode in an interview published Thursday.

The "Shark Tank" star made these remarks as part of a wide-ranging interview where he talked about his political views and his low-cost online pharmacy, Cost Plus Drugs .

"Who would put themselves through that? I can do more from the private sector," Cuban told Goode.

"You can't be president and change health care. You've got to get Congress behind you, and this, and that," he added. " As an entrepreneur, you can change anything. Jensen Huang, what he's doing with Nvidia, he can pretty much define what's going to happen by how he prices things."

To be sure, there has long been speculation that Cuban could run for president one day .

Back in June 2020, Cuban told CNN senior political commentator David Axelrod that he seriously considered a presidential run as an independent candidate that year.

"My family voted it down," Cuban told Axelrod. "Otherwise I would have."

Rumors, however, began swirling again last year after Cuban sold his majority stake in the Dallas Mavericks and announced his departure from "Shark Tank."

But Cuban shot down the speculation again when he told NBC News in November that he had "no plans to run."

Still, Cuban — who is backing Vice President Kamala Harris this election — told Bloomberg in March that he isn't a fan of the two-party system .

"You know, parties vote unilaterally, right? They all vote the same despite representing districts or states that are all across the country. That's just insane," Cuban said in an interview with Bloomberg's "Working Capital," which aired in August.

Cuban did not immediately respond to a request for comment sent outside regular business hours.