NFL odds, Vegas lines, picks, spreads, game predictions: Model loving Ravens, Buccaneers in Week 2, 2024

The Week 2 NFL schedule has arrived and one of the most-anticipated NFL matchups is the Kansas City Chiefs hosting the Cincinnati Bengals. The AFC contenders had vastly different Week 1 results. Kansas City beat the Ravens in the NFL Kickoff Game, while the Bengals were defeated by the Patriots despite being the biggest favorites of the week. The Week 2 NFL odds list Kansas City as a 5.5-point favorite, one of the largest NFL spreads of the day. Other Week 2 NFL lines of note include Lions (-7.5) vs. Buccaneers, Cowboys (-6.5) vs. Saints and Eagles (-6.5) vs. Falcons on Monday Night Football.

In terms of NFL betting line movement, the biggest shift has been in Colts vs. Packers, with Green Bay going from a 4-point favorite to a three-point underdog after a knee injury to Jordan Love in Brazil. All of the Week 2 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 2 NFL picks now .

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on A-rated NFL picks since its inception. The model enters Week 2 of the 2024 NFL season on an incredible 184-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 38-22 roll on A-rated NFL picks since Week 7 of the 2022 NFL season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 2 NFL odds and NFL betting lines on the spread , money line , and over-under , and locked in picks for every NFL matchup. Head here to see every pick .

Top Week 2 NFL predictions

We can tell you one of the model's strongest Week 2 NFL picks is that the Ravens (-8.5, 41.5) cover at home versus the Raiders. The Raiders came into the season with relatively low expectations, particularly on offense. They didn't do much to help their case in Week 1, mustering just 10 points in a 22-10 loss to the Chargers. Quarterback Gardner Minshew had a respectable day, completing 75.8% of his passes for 257 yards. The Raiders, however, failed to get much going on the ground and they let Chargers running back J.K. Dobbins pile up 135 yards on the ground.

Those struggles could easily repeat themselves against a physical Ravens team that came within about an inch of forcing overtime against the defending champion Chiefs in Week 1. SportsLine's model projects that the Raiders score just 17 points in this matchup, helping Baltimore win by double digits and cover the spread in well over 50% of simulations. See which other teams to pick here .

Another one of its Week 2 NFL predictions: the Buccaneers (+7.5, 51) cover on the road versus the Lions . As a franchise, the Buccaneers have been able to deal with the raucous environment that Lions' home games bring as Tampa has had resounding recent success in the Motor City. In the regular season, the Bucs are 4-1 over their last five visits to Detroit, and 7-2 over their last nine trips. The Buccaneers have won three straight regular-season road games overall, despite being underdogs in two of those.

Baker Mayfield is coming off a four-touchdown game with 80% completion percentage and no turnovers. He now gets to face a Lions defense that gave up 317 passing yards to Matthew Stafford in Week 1 and allowed the sixth-most passing yards in 2023. The model projects Mayfield to have more touchdown passes than Jared Goff, and that would allow the Bucs to stay in this one. The model has this game being decided by less than a field goal, as Tampa Bay (+6.5) covers almost 60% of the time. The Under (48.5) is also forecasted to hit in nearly 60% of simulations. See which other teams to pick here .

How to make Week 2 NFL picks

The model has also made the call on who wins and covers in every other game on the Week 2 NFL schedule and just revealed four coveted A-rated picks against the spread. You can only get every pick for every game at SportsLine .

So what NFL picks can you make with confidence, and which four A-rated NFL against-the-spread picks should you lock in now? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $7,000 , and find out.

Week 2 NFL betting odds, lines, spreads

Get Week 2 NFL picks at SportsLine

Thursday, Sept. 12

Bills at Dolphins (-2.5, 48.5)

Sunday, Sept. 15

Raiders at Ravens (-8.5, 41.5)

Chargers at Panthers (+6, 39)

Saints at Cowboys (-6.5, 46.5)

Buccaneers at Lions (-7.5, 51)

Colts at Packers (+3, 41)

Browns at Jaguars (-3, 41.5)

49ers at Vikings (+5.5, 45.5)

Seahawks at Patriots (+3.5, 38.5)

Jets at Titans (+3.5, 40.5)

Giants at Commanders (-1.5, 43)

Rams at Cardinals (-1, 48.5)

Bengals at Chiefs (-5.5, 47.5)

Steelers at Broncos (+2.5, 36.5)

Bears at Texans (-6, 45.5)

Monday, Sept. 16

Falcons at Eagles (-6.5, 47)