Thursday Night Football odds, line, time, spread: Bills vs. Dolphins picks from Buffalo expert on 40-27 roll

The Buffalo Bills (1-0) will visit the Miami Dolphins (1-0) on Thursday Night Football to kick off the Week 2 NFL schedule. This divisional matchup is critical for the AFC East standings, especially for Miami. The Dolphins last won the division in 2003, while Buffalo has won four straight division titles. Buffalo has a 36-28 record in Week 2 all-time, while the Dolphins are 36-21. Dolphins running back Raheem Mostert is out with a chest injury, while fellow running back De'Von Achane is a game-time decision with an ankle injury.

Kickoff from at Hard Rock Stadium in Miami, Fla., is set for 8:15 p.m. ET. Miami is a 2.5-point favorite in the latest Bills vs. Dolphins odds via the SportsLine consensus, while the over/under for total points scored is 48.5. Before locking in any Dolphins vs. Bills picks, make sure to check out the NFL predictions and betting advice from the SportsLine expert Mike Tierney .

A veteran sportswriter whose work appears periodically in the New York Times and Los Angeles Times, Mike Tierney has covered the NFL for decades and reported from seven Super Bowls. Mike is 154-124-9 in the NFL the past two seasons, returning $1,586 to $100 players. Tierney also has a strong read on the Bills. In fact, he is 40-27-4 (+1062) on his last 71 NFL picks in games involving Buffalo. Anyone who has followed him is way up.

Now, Tierney has locked in on Bills vs. Dolphins and just revealed his coveted NFL picks and sports betting predictions. You can head to SportsLine now to see his picks . Here are several NFL odds and NFL betting lines on the spread , money line and over/under for Dolphins vs. Bills:

• Bills vs. Dolphins spread: Miami -2.5
• Bills vs. Dolphins over/under: 48.5 points
• Bills vs. Dolphins money line: Dolphins -137, Bills +117
• BUF: Bills finished with 352 total yards of offense in Week 1
• MIA: Miami went 8-of-16 on third downs in Week 1
• Bills vs. Dolphins picks: See picks at SportsLine

Why the Bills can cover

Buffalo has several playmakers that Josh Allen can throw the ball to. Tight end Dalton Kincaid is an athletic pass-catcher. The Utah product runs crisp routes and is able to play through contact. He's also a willing blocker in the run game. Last season, the 24-year-old ranked second on the team in receptions (73) and third in receiving yards (673) with two touchdowns.

Khalil Shakir gives the Bills a reliable receiver who can win on all three levels. Shakir can be a weapon in open field and can make defenders miss. The Boise State product is coming off a solid performance, notching three catches for 42 yards and one touchdown in Week 1. In 32 games with the Bills, Shakir has 52 catches (68 targets) with 814 yards, four touchdowns, and 15.7 yards per reception. See who to back at SportsLine .

Why the Dolphins can cover

The Dolphins are able to create explosive plays at will. In 2023, Miami ranked first in the NFL in total offense (401.3), firs in passing offense (265.5), and second in points per game (29.2). The Dolphins picked up where they off in the season opener, recording 400 total yards of offense.

Running back De'Von Achane (ankle) owns elite speed and uses his footwork to accelerate away from defenders. The Texas A&M product finished with 24 rushing yards and one rushing score. As a pass-catcher, he had seven receptions (7 targets) for 76 receiving yards. Wide receiver Jaylen Waddle is another dynamic weapon on the outside. Waddle tracks the deep ball well and owns secure hands. In Week 1, the Alabama product snagged five catches for 109 yards and 21.8 yards per reception. See who to back at SportsLine .

How to make Bills vs. Dolphins picks

Tierney is leaning Under the total. He's also found a critical x-factor he says makes side of the spread hit hard. Find out what it is at SportsLine .

So who wins Dolphins vs. Bills on Thursday Night Football, and what critical x-factor makes one side hit hard? Visit SportsLine now to see which side of the Dolphins vs. Bills spread to back, all from the expert who is 40-27 on picks involving Buffalo , and find out.