Self-learning AI shares NFL against the spread, over-under, money-line picks for each 2024 Week 2 game

While several teams are looking to bounce back from rough season-openers, others are trying to build on impressive performances during the Week 2 NFL schedule. Dallas and New Orleans both cruised to double-digit victories last week, with the Saints picking up the biggest blowout win of Week 1. They crushed the Panthers in a 47-10 final, but they are 6.5-point underdogs in the Week 2 NFL odds. Dallas is coming off a 33-17 win at Cleveland despite entering that game as a 1.5-point underdog. It can be difficult to evaluate season-opening performances when making your NFL best bets since there is only one data point for each team. Which Week 2 NFL spreads have value that make them worth targeting with Week 2 NFL bets?

Having NFL betting data to inform your NFL against the spread picks, NFL money line picks, and NFL over/under picks can be a big advantage and give you welcome NFL betting tips. Before you make any Week 2 NFL picks, you need to see the NFL against the spread, over-under, and money line predictions powered by SportsLine AI .

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score.

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.

In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. Last season, SportsLine's AI PickBot hit a whopping 1,674 4.5- and 5-star prop picks. Anyone who has followed it is way up.

For Week 2, the AI PickBot has evaluated the NFL odds and provided NFL predictions for all 16 games. You can only see the AI predictions for the Week 2 NFL schedule here .

Top Week 2 NFL AI picks

After analyzing every game in Week 2, the AI PickBot says the Jaguars cover as three-point favorites at home against the Browns . Jacksonville jumped out to a 14-0 lead in its season opener against Miami before ultimately losing in a 20-17 final, but the Jaguars still covered the spread as 3.5-point underdogs. They rushed for 128 yards and a touchdown, as second-year running back Tank Bigsby had 73 rushing yards on 12 attempts.

Quarterback Trevor Lawrence has several new targets in Gabe Davis and Brian Thomas Jr. to go along with returning weapons Christian Kirk and Evan Engram. Jacksonville's defense also held Miami's offense in check for most of the game, which is a good sign heading into an easier Week 2 matchup. Cleveland's offense continues to struggle with quarterback Deshaun Watson at the helm, and the AI PickBot has the Browns losing by about five points on average. See its other Week 2 football predictions and football picks at SportsLine .

How to make Week 2 NFL picks

In addition, the AI PickBot has generated five A-rated picks for Week 2. You need to see the AI PickBot's picks before making any Week 1 NFL bets of your own. You can only see it at SportsLine .

Who wins and covers each Week 2 NFL game, and which A-rated picks should you target? Visit SportsLine now to see the top NFL picks against the spread, over-under, and on money line, all from the brand-new SportsLine AI PickBot that nailed 1,674 top-rated picks last season .