2024 Week 3 NFL picks, odds, best bets from advanced model: This five-way football parlay pays out 25-1

The Steelers are the only team in the league with two road wins already. They'll make their home debut on Sunday, hosting the Chargers, with Pittsburgh favored by 1.5 points according to the Week 3 NFL odds. This is the only game of the week with both teams 2-0 against the spread this season, and incorporating over/under picks into this game's predictions could result in winning Week 3 NFL parlay picks.

While their spread records don't give you an indication as to which way to lean, the Under is a combined 4-0 for the teams in 2024. You don't have to include spread picks to form Week 3 NFL parlay bets, as you could also add a money line bet to your Week 3 NFL predictions. Before you make any Week 3 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 3 of the 2024 NFL season on an incredible 187-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 41-22 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has scoured the Week 3 NFL odds and locked in five confident NFL best bets. If you successfully parlay its picks, you'd be looking at a massive payout of around 25-1. You can only see the model's Week 3 NFL picks at SportsLine .

Top Week 3 NFL picks

After simulating every game 10,000 times, the model is high on the Seattle Seahawks (-4.5) cover at home against the Miami Dolphins . Miami is known as a front-running team that beats good teams but loses to better competition. That's evident in its spread record since the start of last year, as the Dolphins are just 1-6 ATS as an underdog over that span. No team has a worse ATS record as an underdog over that span, and Miami is also 1-4 ATS as an away underdog since the start of last year.

The Seahawks have beaten the Dolphins in each of their last two meetings, in addition to their two most recent matchups in the Pacific Northwest. It's been 23 years since the Dolphins made the 3,330-miles trip from South Florida to Seattle to defeat the Seahawks. Now, they'll have to attempt to do that without QB Tua Tagovailoa, and Miami failed to cover in its first two games with him under center. Add in that reigning TD leader Raheem Mostert is banged up and missed last game, and the model has Seattle covering almost 60% of the time. See which other NFL parlay picks to make here.

How to make Week 3 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including a home underdog that covers the spread in well over 60% of simulations, defying oddsmakers everywhere. You can only see the model's NFL Week 3 best bets and parlay at SportsLine .

What are the model's top Week 3 NFL picks, and which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 3 NFL best bets from a model on an 187-130 run on top-rated picks , and find out.