2024 college football picks, Week 5 odds, lines, best bets from proven expert

Fresh off a thrilling last-minute victory over USC in their Big Ten opener, the Michigan Wolverines will host the Minnesota Golden Gophers on Saturday in "The Big House." The defending national champions rose to No. 12 in the AP Top 25 after their win over the Trojans and now they're favored by 10.5 in the latest Week 5 college football odds via SportsLine consensus. So can the Wolverines get another needed win to keep pace in the Big Ten with a difficult stretch of the schedule looming?

Meanwhile, No. 3 Ohio State will begin its Big Ten season on the road against Michigan State on Saturday. The Buckeyes are 23.5-point road favorites in the Week 5 college football lines. Before locking in any Week 5 college football picks, be sure to see the top Week 5 college football expert picks, predictions and best bets from Thomas Casale .

A frequent guest on national radio and TV shows to discuss college sports, Casale has been betting -- and winning -- for more than 30 years. Over the past two college football seasons, Casale is 122-92-5 (57%) overall on his college football picks and 26-8 (76.4%) in bowl games -- all publicly documented. Anybody who has followed him is way up.

Now, he has turned his attention to the Week 5 college football odds and is sharing his best bets over at SportsLine. Get his top college football picks at SportsLine .

Top Week 5 college football expert predictions

One of Casale's top Week 5 college football picks: He is backing No. 2 Georgia to win on the money line against No. 4 Alabama for a -117 payout. Despite the fact that Georgia is only a year removed from back-to-back national championships, this rivalry was dominated by Alabama during the Nick Saban era. However, Saban is gone and Kalen DeBoer is now at the helm in Tuscaloosa. Kirby Smart has leaned on his protege Dan Lanning of Oregon to help prep for DeBoer's high-powered offense and Casale is highlighting one particular matchup as the reason why he's backing Georgia here.

"Both teams had a week off to prepare and I'm expecting a much different Bulldogs squad on Saturday. I still have concerns about the Tide's defensive front and think Georgia will be able to exploit it," Casale told SportsLine. "Wisconsin was able to rush for 149 yards with zero threat of a passing game ... Georgia has won 28 straight regular season SEC games and 16 in a row on the road. I took the money line, but would also bet Georgia on the spread at anything under -3." See what other picks Casale likes at SportsLine .

How to make Week 5 college football picks

Casale has found another college football pick he loves, including backing a potent offense in a game where "both teams should struggle to get stops." You can only see his picks at SportsLine .

What are the best bets for Week 5 of college football, and which offense you trust to come out ahead in a high-scoring battle? Visit SportsLine now to see Thomas Casale's college football best bets, all from a proven college football handicapper who has gone 26-8 on bowl games the past two seasons , and find out.