Week 5 NFL trends, predictions, bets, odds: Sharp money picks by professional football bettors in Las Vegas

One of the marquee matchups on the Week 5 NFL schedule is an AFC showdown between the Buffalo Bills (3-1) and Houston Texans (3-1) on Sunday at NRG Stadium. The Bills suffered their first loss of the season in Week 4, falling to the Baltimore Ravens , 35-10, while the Texans are coming off a 24-20 win over the Jacksonville Jaguars . The Texans are 1-point favorites at home in the latest Week 5 NFL odds after being one-point underdogs earlier this week, but will be without running back Joe Mixon, who is sidelined with an ankle injury. Is Bills vs. Texans among the Week 5 NFL games that NFL sharps are targeting in Las Vegas? Before making NFL Week 5 picks or bets, you need to see the against the spread picks from the sharp money gamblers and professional football bettors in Las Vegas .

Sharp money bettors are notorious in Las Vegas for finding value in point spreads and betting lines that casual bettors may not see. These professional bettors are respected by sportsbooks in Vegas and all around the world, and their betting action often causes bookmakers to change their lines.

Jay Kornegay, EVP of the Westgate SuperBook in Las Vegas, joined SportsLine NFL expert Jimmie Kaylor to share who the Vegas sharps are backing in the Week 3 NFL odds. Kornegay is a longtime oddsmaker at the SuperBook, and has been a key player on the Vegas bookmaking scene for more than 25 years. He was inducted into the Sports Betting Hall of Fame Class of 2024.

In Week 3 and Week 4 (the first two weeks of this article), the sharps have been crushing the sportsbooks, going a combined 6-1 against the spread on their NFL picks.

Now that the sharps in Las Vegas have had a chance to digest the Week 5 NFL odds, they've start to lock in their picks for the Week 5 NFL schedule. You can only see them by heading to SportsLine .

Top Vegas NFL sharp money picks for Week 5

For Week 5, one of the Sharp Money plays the SuperBook has taken is the Kansas City Chiefs (-5.5, 43.5) covering at home against the New Orleans Saints on Monday Night Football. The Chiefs are unbeaten through four weeks, and have gone 2-1-1 against the spread. While they haven't been winning in dominant fashion, the two-time defending Super Bowl champions continue to find ways to win games.

Two-time NFL MVP Patrick Mahomes is still working on his chemistry with his new group of wide receivers, but the 29-year-old quarterback continues to make big plays at big moments in games. Through four weeks, he has thrown for 904 yards, six touchdowns, and five interceptions. The Chiefs also rank near the top of the NFL, allowing 18.0 points per game this season, and the line for this game has fallen two points from the opener. See who else the NFL Vegas sharps are backing in Week 5 here .

How to get sharp money Vegas NFL ATS picks for Week 5

The Vegas sharps have also targeted two other NFL games and already locked in their against the spread picks, including on a surging team who covers against a division-rival. You can only see who they are backing in Week 5 here .

Which NFL teams are the sharp money bettors in Las Vegas backing in Week 5? And which team is getting all the attention? Visit SportsLine now to see the top NFL picks and best bets from respected professional football bettors in Las Vegas , and find out.