NFL odds, Vegas lines, picks, spreads, game predictions: Model targets Falcons, Commanders in Week 6, 2024

Bo Nix and the Denver Broncos have won three consecutive games and will host the Los Angeles Chargers for an AFC West rivalry in Week 6. The Broncos have won five consecutive home games against the Chargers, but Denver is a 3-point underdog according to the latest Week 6 NFL odds. The Broncos are also 7-3 against the spread in their last 10 meetings against the Chargers, one of the NFL betting trends many could take into account before locking in their Week 6 NFL picks.

There are several other divisional matchups on the Week 6 NFL schedule, including Buccaneers vs. Saints (+3.5), Titans vs. Colts (+2.5), Falcons vs. Panthers (+6) and Bills vs. Jets (+2.5). All of the Week 6 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 6 NFL picks now .

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2024 NFL season on an incredible 10-2 hot streak on top-rated NFL picks this year. Longer term, it is on a 191-131 roll on top-rated NFL picks that dates back to the 2017 season and a 45-23 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 6 NFL odds and NFL betting lines on the spread , money line , and over-under , and locked in picks for every NFL matchup. Head here to see every pick .

Top Week 6 NFL predictions

We can tell you one of the model's strongest Week 6 NFL picks is that the Falcons (-6, 47) cover the spread versus the Panthers . Carolina's offense looked anemic with Andy Dalton under center in last week's loss to the Chicago Bears. Dalton completed 18 of 28 passes for 136 yards and one interception in the 36-10 setback. Running back Chuba Hubbard was the lone bright spot for the Panthers with 97 rushing yards and a touchdown.

However, Carolina's defense was exposed in last week's loss, giving up 304 passing yards to rookie quarterback Caleb Williams. On Sunday, the Panthers will face an Atlanta offense that has found its rhythm. Quarterback Kirk Cousins threw for a franchise record 504 yards in the Falcons' 36-30 victory over the Buccaneers last Thursday. In addition, the Falcons are 12-5 in their past 17 meetings against the Panthers, while Carolina is just 1-13 in its last 14 matchups against an opponent from the NFC. That's a big reason why Atlanta (-6) is projected to win by at least a touchdown and cover in well over 50% of simulations. See which other teams to pick here .

Another one of its Week 6 NFL betting predictions: the Commanders (+6.5, 51.5) cover on the road versus the Ravens . Only the undefeated Vikings and Chiefs have longer winning streaks than Washington's four straight victories, and they've covered in each of those four as well. Its last two victories have both come by at least 21 points, while the team ranks second in the league with 31 points per game.

That potent offense should provide a problem for a Ravens defense which has uncharacteristically struggled. After leading the NFL in scoring defense a year ago, Baltimore ranks just 26th this year, giving up nearly 10 more ppg than in 2023. Joe Burrow just tossed five TD passes against Baltimore, which has allowed the second-most passing yards this season. With Jayden Daniels ' 77.1 CMP% leading the NFL, he should be able to dice up the Ravens defense. The SportsLine model has the Commanders (+6.5) covering well over 50% of the time, while the Over (52) also hits in well over 50% of simulations. See which other teams to pick here .

How to make Week 6 NFL picks

The model has also made the call on who wins and covers in every other game on the Week 6 NFL schedule and just revealed two underdogs that outright win, potentially giving you a huge payday. You can only get every pick for every game at SportsLine .

So what NFL picks can you make with confidence, and which two must-see underdogs should you lock in now? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $7,000 , and find out.

Week 6 NFL betting odds, lines, spreads

Get Week 6 NFL picks at SportsLine

Thursday, Oct. 10

49ers at Seahawks (+3.5, 49.5)

Sunday, Oct. 13

Jaguars vs. Bears -- in London (-2.5, 44.5)

Commanders at Ravens (-6.5, 51.5)

Cardinals at Packers (-5.5, 47.5)

Texans at Patriots (+7, 38)

Buccaneers at Saints (+3.5, 41.5)

Browns at Eagles (-9.5, 42.5)

Colts at Titans (-2.5, 43)

Chargers at Broncos (+3, 35.5)

Steelers at Raiders (+3, 36.5)

Falcons at Panthers (+6, 47)

Lions at Cowboys (+3, 52)

Bengals at Giants (+3.5, 48)

Monday, Oct. 14

Bills at Jets (+2.5, 41)