The Substance Trailer Previews Demi Moore & Margaret Qualley Body Horror Movie

Mubi has released The Substance trailer for its upcoming body horror thriller, starring Golden Globe nominees Demi Moore and Margaret Qualley . The film had its world premiere last May at the 2024 Cannes Film Festival. It is currently scheduled to arrive in theaters on September 20.

“The film follows Elisabeth Sparkle, a former A-lister past her prime and suddenly fired from her fitness TV show by repellent studio head Harvey,” reads the synopsis. “She is then drawn to the opportunity presented by a mysterious new drug: THE SUBSTANCE. All it takes is one injection, and she is reborn – temporarily – as the gorgeous, twentysomething Sue. The only rule? Time needs to be split: exactly one week in one body, then one week in the other. No exceptions. A perfect balance. What could go wrong?

Check out The Substance trailer below ( watch more trailers ):

Who is in The Substance trailer?

The trailer features Moore as Elisabeth Sparkle, Qualley as Sue, and Dennis Quaid as Harvey. Additional cast members include Hugo Diego Garcia (Death and Other Details), Phillip Schurer (The Consolation), Joseph Balderrama (The Batman), Robin Greer (The Count of Monte Cristo), Gore Abrams (Marinette), Oscar Salem (Vigil), Olivier Raynal (The Spanish Apartment), Matthew Géczy (Chip ‘N’ Dale: Park Life), and more.

The Substance is written, directed, and produced by Coralie Fargeat, who won the Best Screenplay award at the Cannes Film Festival. The creative team also includes cinematographer Benjamin Kracun, production designer Stanislas Reydellet, special makeup effects designer Pierre-Olivier Persin, composer Raffertie, and more. It is a production by Working Title, Blacksmith and A Good Story.

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