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Article written by Emily Spencer, Edinburgh Napier University. Imagine a future where the smell of menthol could alleviate some of the worst symptoms of Alzheimer’s disease. This might sound like science fiction, but innovative new research is making it a potential reality. Scientists have discovered that when mice with...

Alzheimer’s patients could protect memory simply by inhaling menthol, mouse study shows

Summary: Researchers reversed Alzheimer’s symptoms in mice using a synthetic peptide, PHDP5, that targets brain function. The study shows that PHDP5 can cross the blood-brain barrier and restore memory by improving synaptic function. The treatment could delay cognitive decline if administered early. This breakthrough paves the way for new...

Synthetic Peptide Reverses Alzheimer’s Symptoms

The US Food and Drug Administration (FDA) approved a drug made by Eli Lilly on Tuesday that is designed to treat the early symptoms of Alzheimer's disease. The drug known as Kisunla should be used by "patients with mild cognitive impairment or mild dementia stage of disease," the FDA said in a statement announcing its decision to approve the drug.

FDA Approves Eli Lilly's New Alzheimer's Drug For Early Disease Symptoms

The early signs of dementia in women include memory loss and confusion. Dementia is a collective term that describes various symptoms of cognitive decline, such as forgetfulness, confusion, and changes in behavior. It is not a specific disease but a group of conditions characterized by impairment of at least two brain functions, such as memory loss and judgment.

Early signs of dementia in women

ScienceAlert


Researchers have discovered how a cell surface protein called Aplp1 can play a role in spreading material responsible for  Parkinson's disease from cell-to-cell in the brain.
Promisingly, an FDA-approved  cancer drug that targets another protein called Lag3 – which interacts with Aplp1 – blocks the spread in mice, suggesting a potential therapy may already exist.



					
			

In a new paper, an international team of scientists describes how the two proteins work together to help harmful alpha-synuclein protein clumps get into brain cells.
"Now that we know how Aplp1 and Lag3 interact, we have a new way of understanding how alpha-synuclein contributes to...

Parkinson's Discovery Suggests We May Already Have an FDA-Approved Treatment

The FDA has authorized an Investigational New Drug (IND) application for Synaptogenix, Inc.’s Bryostatin-1 as a potential treatment for multiple sclerosis (MS). The fully-funded, open-label clinical trial will be held and managed at Cleveland Clinic Neurological Institute's Mellen Center for Multiple Sclerosis. The study will utilize 7T MRI technology to identify biomarkers for evaluating Bryostatin-1's impact on the brain.

Clinical Trial for Multiple Sclerosis Treatment to Use 7T MRI

The FDA has approved a new Alzheimer’s drug called Kisunla from Eli Lilly, which can modestly slow the progression of the disease in patients with mild or early dementia caused by Alzheimer’s. This marks the second drug to convincingly show a delay in cognitive decline in Alzheimer’s patients,...

Second Alzheimer’s drug approved by FDA

TIME

The new research is early, but it's a hopeful advance for patients with the neurological condition.

A Potential Parkinson's Treatment Has Promising Results

The U.S. Food and Drug Administration (FDA) has given Iregene Therapeutics the green light to launch a clinical trial testing its cell therapy NouvNeu001, being developed for moderate to advanced Parkinson’s disease. According to the company, this marks a significant milestone, with NouvNeu001 becoming the world’s first chemically induced...

FDA OKs Parkinson’s clinical trial to test NouvNeu001 cell therapy

TheConversationAU

What’s the difference? is a new editorial product that explains the similarities and differences between commonly confused health and medical terms, and why they matter. Changes in thinking and memory as we age can occur for a variety of reasons. These changes are not always cause for concern. But when they begin to disrupt daily life, it could indicate the first signs of dementia.

What’s the difference between Alzheimer’s and dementia?

Newark, NJ

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Morristown Minute

NEWARK, N.J. – Eight individuals associated with the "793 Bloods" street gang, a subset of the national Bloods gang, have been charged for their roles in a Newark-based drug trafficking organization, U.S. Attorney Philip R. Sellinger announced.

Eight '793 Bloods' Gang Members Charged in Newark Drug Network

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Total Apex Sports & Entertainment

People have different levels of maturity. An individual’s age or upbringing can make them possess certain traits. Yet, most people believe that one matures as they grow old. On the contrary, some zodiac signs appear childish in old age. They are jumpy and careless. This strains their relationships with signs who misunderstand them. Air and fire signs are temperamental and some people refer to them as being childish. How can you identify an immature sign?

3 Zodiac Signs Who Are Immature

This announcement follows an earlier FDA decision to grant approval to the company’s tissue-based comprehensive genomic profiling test FoundationOne CDx for the same therapy and indication in August 2023. The FDA has approved the liquid biopsy test FoundationOneLiquid CDx for use as a companion diagnostic in identifying patients with...

FDA approves FoundationOneLiquid CDx for niraparib/abiraterone in mCRPC

Fibromyalgia and sleep apnea both disrupt nighttime sleep. Chronic pain from fibromyalgia can affect your ability to fall or stay asleep. Sleep apnea can increase symptoms of fibromyalgia. Are you finding yourself waking up frequently in the night and having a hard time getting up in the morning? Is fatigue...

The Link Between Fibromyalgia and Sleep Apnea

The Food and Drug Administration (FDA) granted approval to Eli Lilly for their Alzheimer's drug donanemab. This decision marks a notable expansion of the treatment options available for individuals suffering from this debilitating disease in the United States. Eli Lilly's Alzheimer's Drug Donanemab Approved by FDA. Eli Lilly has finally...

FDA Approves Eli Lilly's Alzheimer’s Drug Donanemab, Expanding US Treatment Options

The Independent

A family history of Alzheimer’s disease on the mother’s side might increase the chances of someone developing the condition, new research suggests.Whether a person inherits risk of Alzheimer’s from their mother or father influences the danger of changes in the brain that lead to disease, according to the new study.After evaluating 4,400 adults aged 65 to 85 who had memory loss and trouble solving problems, the researchers found those with a history of Alzheimer’s on either their mother’s side, or both parents’ sides, had increased proteins (amyloids) linked to Alzheimer’s in the brain.The findings suggest that considering sex-specific parental history...

Alzheimer’s disease on mother’s side linked to ‘increased risk’ of the condition

Ohtuvayre is the first inhaled product with a novel mechanism of action for chronic obstructive pulmonary disease to be approved in 20 years. The FDA has approved Verona Pharma’s Ohtuvayre (ensifentrine) for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adult patients. Classified as a first-in-class selective dual inhibitor of phosphodiesterase 3 and 4 (PDE3 and PDE4), the treatment combines bronchodilator and non-steroidal anti-inflammatory effects in one molecule. According to the company, this marks the first time in 20 years that an inhaled product with a novel mechanism of action has been approved for COPD maintenance.1.

FDA Approves Verona’s Ohtuvayre for the Maintenance Treatment of Chronic Obstructive Pulmonary Disease

The U.S. has entered the “fourth wave” of the overdose epidemic, characterized by skyrocketing use of stimulants like methamphetamine. A new study found that a duo of drugs is effective at curbing methamphetamine-positive drug tests by 27% compared to a placebo. “These findings have important implications for pharmacological...

No FDA-Approved Meth Treatments Exist, But New Study Offers Hope

Illinois State

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Chicago, IL

Chicago Happenings

Every year, new laws that were passed the prior year go into effect on July 1. In 2024, a number of new laws will begin this Monday. Among them include higher wages for tipped employees, a gas tax increase, and driver's licenses for undocumented immigrants.

New Laws July 1: Driver's Licenses for Undocumented Migrants, Raises for Tipped Workers, and More

Virginia State

Cheryl E Preston

Virginia fans of The Bold and the Beautiful are pretty much unified in their expectations of what will happen between Thomas Forrester (Matthew Atkinson) and Paris Buckingham (Diamond White), who recently announced their engagement.

The Bold and the Beautiful fans believe Thomas will dump Paris for Hope

NewsBreak

New FDA approved Alzheimer's treatment targets early stage patients

\"For 30 years we didn't have anything but medications for those symptoms of this disease, and now there are medications that may give these families more...

"For 30 years we didn't have anything but medications for those symptoms of this disease, and now there are medications that may give these families more...

New FDA approved Alzheimer's treatment targets early stage patients

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