Houston, TX

Columbus, OH

Two separate clinical trials have found that a class of drugs that stymie inflammation may improve the effectiveness of commonly used immunotherapies. In both trials—one involving people with lung cancer and the other with lymphoma—adding a JAK inhibitor to an immune checkpoint inhibitor shrank tumors in more than half of the participants.

Drug Combo JAKs Up Immunotherapy in Two Clinical Trials

Davis, CA

Preventing the next pandemic begins before diseases emerge. This “pre-emergence” phase is the focus of a new center funded by the U.S. National Science Foundation and led by the University of California, Davis. Supported with $18 million over seven years, the U.S. National Science Foundation Center for Pandemic...

New NSF Center for Pandemic Insights

Study Title: Belzutifan Versus Everolimus for Advanced Renal-Cell Carcinoma. Publication: New England Journal of Medicine, August 22, 2024. Dana-Farber Cancer Institute authors: Toni K. Choueiri, MD. Summary: The LITESPARK-005 phase 3 clinical enrolled 746 patients with metastatic clear cell renal cell carcinoma (ccRCC) who had progressed after treatment with both...

Pivotal study supports belzutifan approval for patients with advanced kidney cancer

The field of precision medicine, especially in the context of cancer immunotherapy, has seen significant advancements in recent years. Precision medicine tailors treatment to the unique genetic and molecular profile of each patient, moving away from conventional one-size-fits-all approaches. This personalized strategy aims to minimize side effects and maximize therapeutic efficacy. A key component of this approach is the use of immune checkpoint inhibitors (ICIs), monoclonal antibodies that target immunosuppressive molecules such as PD-1, PD-L1, and CTLA-4. These ICIs have demonstrated considerable success in treating various types of cancer by enhancing the body's immune response against tumor cells.

Recent developments of vaccines as a precision medicine approach to cancer immunotherapy

Philadelphia, August 20, 2024 – According to new research, cognitive impairments in psychotic disorders, such as schizophrenia and bipolar disorder, are linked to brain network organization. This link between cognition and brain networks is present in individuals considered at-risk for psychotic disorders even prior to their first psychotic break. This groundbreaking study in Biological Psychiatry, published by Elsevier, suggests an opportunity for early diagnosis and intervention for these treatment-resistant symptoms.

Groundbreaking study shows promise for early detection and intervention in psychotic disorders such as schizophrenia

Stanford, CA

Neuroscientists at Stanford have linked Alzheimer’s disease to the disruption of brain metabolism via the kynurenine pathway, which is affected by amyloid plaque and tau proteins. Their research has demonstrated that drugs blocking this pathway can restore cognitive function in Alzheimer’s mice by improving brain metabolism. This discovery not...

Stanford Reverses Cognitive Decline in Alzheimer’s With Brain Metabolism Drug

Toni English’s medical team was giddy. It was six weeks after English had completed an experimental cancer treatment, and she had arrived at the Orlando Health Cancer Institute in Florida with her husband to see the results of her latest scan. Her team gathered in a patient exam room...

A newly approved ‘living drug’ could save more cancer patients’ lives

Most cancer patients suffer poor mental health but few patients or clinicians are empowered to address it. There is an unintended collusion in the health system to deny the effect cancer can have on mental health. Managing mental health should be an integral part of the treatment and care for...

How to Treat Cancer in Its Entirety

Health

Medically reviewed by Christopher Lee, MDMedically reviewed by Christopher Lee, MDHeart cancer develops when abnormal cells in the heart muscle or surrounding tissues grow uncontrollably, forming a malignant (cancerous) tumor. Cancerous heart tumors (known as cardiac sarcomas) are extremely rare, accounting for less than 0.028% of all cancer diagnoses annually.  Secondary heart cancer is when cancer cells metastasize (spread) to the heart from a tumor that started in nearby organs or body tissues. Secondary heart cancer is about 30 to 50 times more common than primary heart cancer. However, it is still rare, affecting approximately 10% of people with lung cancer,...

Signs and Symptoms of Heart Cancer

Louisiana State

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Natrona County, WY

Houma, LA

WyoFile

The crane operator who was killed on the job earlier this month at a wind-energy construction site in remote Natrona County was driving a crane that rolled into a pond, according to a Natrona County Sheriff’s Office’s incident report obtained by WyoFile.

Deadly workplace accident trapped victim in a Natrona County pond

Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function. It is a major risk factor for cirrhosis and liver cancer. And because treatment options are limited, MASH is the second leading cause for liver transplants...

Macrophage mix helps determine rate and fate of fatty liver disease

Ascites is a buildup of fluid in your abdominal cavity. About one-third of people with ovarian cancer will have ascites at the time of their initial cancer diagnosis. Most generally healthy people have very little free fluid inside their abdomen — usually no more than 20 milliliters. But when you have ascites, large amounts of fluid collect in the free space around your organs.

Understanding Ascites and Ovarian Cancer

Immunotherapy May Facilitate Surgery and Improve Outcomes for Patients With High-Risk Liver Cancer. Patients with liver cancer who received immune checkpoint inhibitors (ICIs) before surgery—including those who would not have been eligible for surgery by conventional criteria—had similar outcomes to patients who received surgery upfront, according to results from a retrospective study published in Cancer Research Communications, a journal of the American Association for Cancer Research (AACR).

Immunotherapy Before Surgery May Improve Outcomes for Patients With Liver Cancer

Pelage Pharmaceuticals, a clinical-stage regenerative medicine company, has initiated its Phase 2a trial for PP405, a topical small molecule designed to treat androgenetic alopecia. The study will evaluate safety and efficacy in 60 diverse participants, including both women and men. The company has secured $14 million in Series A-1 financing, led by GV, following positive Phase 1 results. This funding will accelerate the clinical program for this innovative hair loss treatment.

Regenerative Hair Loss Treatment Targets Dormant Follicle Stem Cells [Clinical Trial]

Dr. Oleg Dmitriev (PhD), a professor in the department of Biochemistry, Microbiology and Immunology, and oncology professor Dr. Franco Vizeacoumar (PhD) in USask’s College of Medicine were two of the authors of a research paper recently published in eLife identifying the function of a less-understood cell protein referred to as MEMO1.

Iron Metabolism Could Be Targeted To Treat Aggressive Form of Cancer

The Conversation U.S.

Targeting the key players that help your body regulate metabolism could reverse disease progression, including cognitive decline related to Alzheimer’s disease.

What links aging and disease? A growing body of research says it’s a faulty metabolism

Aurora, CO

David Heitz

An Aurora City Council member has suggested shoplifters in the city should be publicly shamed for stealing. Council member Steve Sundberg, a small business owner, made his remarks during the Planning and Community Development Policy Committee meeting Aug. 14. He did not offer specifics but hinted he and the police department may have something in the works. He likened the shaming to the public humiliation of johns on Colfax Avenue "back in the day."

Shaming shoplifters suggested by Aurora City Council member

Florida State

Jacksonville, FL

Jacksonville Today

Jacksonville Sheriff T.K. Waters said he will consider more DUI patrols if voters legalize recreational marijuana use in Florida. Voters will consider Amendment 3 in November. It would allow adults 21 or older to possess, purchase or use marijuana products and marijuana accessories for non-medical purposes.

More DUI patrols possible if marijuana issue passes

Tens of millions of Americans are being exposed to tobacco content on streaming services, according to new research from The University of Texas MD Anderson Cancer Center. The researchers found that the odds of encountering tobacco products being advertised, marketed or promoted on these platforms increased based on race, ethnicity, socioeconomic status and smoking habits.

Americans face disparities in exposure to tobacco on streaming platforms

Bellaire, TX

Galena Park, TX

Pasadena, TX

South Houston, TX

Channelview, TX

Humble, TX

Missouri City, TX

Pearland, TX

Deer Park, TX

Stafford, TX

NewsBreak

MD Anderson receives over $21.4 million in CPRIT funding to support research and launch new core facilities

HOUSTON ― The University of Texas MD Anderson Cancer Center today was awarded nine grants totaling over $21.4 million from the Cancer Prevention and Research Institute...

MD Anderson receives over $21.4 million in CPRIT funding to support research and launch new core facilities

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