Researchers have discovered a new pathway used by cancer cells to infiltrate the brain and developed a promising therapy that targets this pathway with CAR T cells. Their study showed significant preclinical success in increasing survival and eradicating tumors in animal models of glioblastoma and other brain cancers. A team...

Brain Cancer Breakthrough: New Therapy Destroys Glioblastoma in Recently Unveiled Pathway

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Medical News Today

A ketogenic diet, combined with a new therapy, may help starve pancreatic cancer cells and shrink tumors, a mice study has shown.

A ketogenic diet may help block the development of pancreatic cancer

How would you summarize your study for a lay audience?. Immune checkpoint inhibitors are cancer fighting drugs that help the immune system do its job of detecting and attacking tumor cells. Programmed Cell Death 1 (PD-1) is a common target for this type of drug—it is a protein that sits on the surface of T cells and helps regulate the immune system’s response to neighboring cells, both normal and cancerous. While most research efforts to date have focused on PD-1’s role in T cells, it is also active in many other kinds of cells—including cancer cells as first demonstrated by the Schatton laboratory.

Research spotlight: Key regulators of pd-1 in melanoma cells and the immune system’s response

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Fareeha Arshad

Immunotherapy, a critical approach in cancer treatment, harnesses the body's immune system to combat tumours. A recent study from a research group at MedUni Vienna and Vienna General Hospital revealed that targeting specific enzymes in dendritic cells (DCs), a vital immune system component, can enhance anti-tumour immunity. The findings, published in Cell Reports, suggest potential new therapeutic strategies in immunotherapy.

Breakthrough in Immunotherapy by Manipulating Dendritic Cell Enzymes

Researchers at the Centre for Genomic Regulation (CRG), the University of the Basque Country (UPV/EHU), Donostia International Physics Center (DIPC) and the Fundación Biofisica Bizkaia (FBB, located in Biofisika Institute) have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells. The findings, published today in a study in the journal Nature Machine Intelligence, pave the way for improved diagnostic techniques and new monitoring strategies for disease.

AI spots cancer and viral infections at nanoscale precision

Being a health writer, I have a good grasp of how our immune system works. I’ve written about it often, including how to know if your immune system isn’t working properly, how to slow immune system aging and how inflammation can turn your immune system harmful. And when...

Boost your cancer-killing white blood cells in 30 minutes

Melanoma is a type of skin cancer that can spread rapidly to other areas. However, there are also slow-growing types that may develop over many years. Melanoma is not as common as other types of skin cancer. However, unlike other skin cancers, melanoma has a high risk of spreading to other areas, which makes it the most dangerous type.

How fast does melanoma spread?

Cancer Health

In 2006, Diana Lindsay, who had never so much as held a cigarette, was diagnosed with stage 4 lung cancer. It had metastasized to both lungs, her brain and lymph nodes. Keith Eaton, MD, PhD, clinical director of thoracic, head and neck medical oncology at Fred Hutch Cancer Center, told her that a typical patient in this situation would have about nine months to live. But he also observed that she seemed remarkably strong and vital. “He said, ‘You don’t look like my normal lung cancer patient,’” said Lindsay, who had just returned from a business trip to Europe. She was 54 at the time. “He didn’t want to take away the health I had for the limited time I had to live.”

20 Years Since an EGFR Discovery, a Woman With Stage IV Lung Cancer Is Thriving

A drug that was developed to treat pancreatic cancer has now been shown to increase symptom-free survival in preclinical medulloblastoma models – all without showing signs of toxicity. Medulloblastoma is the most common malignant brain tumor in children. Survival rates vary according to which one of the four subtypes...

Drug developed for pancreatic cancer shows promise against most aggressive form of medulloblastoma

Health

Medically reviewed by Christopher Lee, MDMedically reviewed by Christopher Lee, MDHeart cancer develops when abnormal cells in the heart muscle or surrounding tissues grow uncontrollably, forming a malignant (cancerous) tumor. Cancerous heart tumors (known as cardiac sarcomas) are extremely rare, accounting for less than 0.028% of all cancer diagnoses annually.  Secondary heart cancer is when cancer cells metastasize (spread) to the heart from a tumor that started in nearby organs or body tissues. Secondary heart cancer is about 30 to 50 times more common than primary heart cancer. However, it is still rare, affecting approximately 10% of people with lung cancer,...

Signs and Symptoms of Heart Cancer

The Independent

 A new vaccine designed to prime the immune system to recognise and fight lung cancer has been tested on UK patients for the first time.Researchers leading the trial have said that BioNTech’s BNT116 vaccine could improve survival rates among people with the disease, and hope that it could eventually become the standard of care worldwide.It works by presenting the immune system with tumour markers from non-small cell lung cancer, the most common form of the disease, to prime the body to fight cancer cells expressing these markers.“Lung cancer is a disease that occurs when cells in the lungs grow...

The lung cancer signs everyone needs to know about as new vaccine announced

Lung cancer is the most common cancer worldwide, taking 1.8 million lives annually. Traditionally combated using surgery, radiation, and chemotherapy, survival rates have improved. But now, a new vaccine is looking to stop the cancer by harnessing the body's immune system. Trials for the world's first lung cancer vaccine have started in 34 research centers across seven countries.

World’s First Lung Cancer Vaccine Trials Are Now Running in Seven Countries

The Healthy 

The thyroid is a small, butterfly-shaped gland nestled at the front of the neck just beneath the skin, and plays an essential role in the body’s overall function. It is responsible for producing and releasing hormones that regulate metabolism, energy levels, and body temperature. When the thyroid isn’t functioning well or develops cancer, it can have widespread effects on throughout the body.

“Here’s How I Knew I Had Thyroid Cancer”: One Patient’s Story When Emotional & Hormonal Symptoms Crept Up

Thyroid cancer stages range from 1 to 4 (sometimes referred to in Roman numerals as I, II, III, and IV). Stage 4 thyroid cancer is the most serious; stage 1 is the least severe. The stage of someone's cancer is determined by the size and spread of cancer cells from a tumor's primary site, in this case, the thyroid gland.

What Are the Stages of Thyroid Cancer?

When lung cancer spreads beyond the lungs, it usually first affects nearby lymph nodes. But doctors don’t usually consider lung cancer to be “metastatic” until it has spread to more distant parts of the body. Lung cancer can spread throughout the body in several ways. Cancerous cells...

Where Lung Cancer Spreads First

Over 12,000 feet below the surface of the sea, in a region of the Pacific Ocean known as the Clarion-Clipperton Zone (CCZ), million-year-old rocks cover the seafloor. These rocks may seem lifeless, but nestled between the nooks and crannies on their surfaces, tiny sea creatures and microbes make their home, many uniquely adapted to life in the dark.

Marine science oxygen produced in the deep sea raises questions about extraterrestrial life

When Eduardo Davila, PhD, talks about his work to leverage a patient’s immune system to fight cancer, it reminds him of a TV show he watched as a child: “The Six Million Dollar Man.” The show’s main character, after a devastating accident, is rebuilt into a better and stronger version of himself.

Better. Stronger. Faster. Scientists Rebuild Cancer-Killing Cells [PODCAST]

Medically reviewed by Marla Anderson, MDMedically reviewed by Marla Anderson, MDNon-small cell lung cancer (NSCLC) is a type of cancer that begins in the tissues of the lungs. About 80-85% of all lung cancer cases in the United States are classified as NSCLC. NSCLC occurs when the cells that line the surface of the lung airways change and mutate. When these abnormal cells rapidly divide and multiply, they lead to cancer. The most common cause of NSCLC is smoking, with about 90% of lung cancer cases being related to tobacco smoke exposure. It is possible to be diagnosed with NSCLC if you...

What Causes Non-Small Cell Lung Cancer (NSCLC)?

Small cell lung cancer (SCLC) is a fast-growing cancer that develops in cells within the lung. A range of medical tests and procedures are available to help doctors diagnose SCLC and create an appropriate treatment plan. Lung cancer is a complex disease comprising various subtypes. A person who receives a...

How do doctors diagnose small cell lung cancer?

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Oncologists share the causes of endometrial cancer and how to lower your risk.

Here's What Actually Causes Endometrial Cancer, According to Oncologists

NewsBreak

New way to potentially slow cancer growth

LA JOLLA, CA—Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays...

New way to potentially slow cancer growth

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