Philadelphia, PA

Mountain View, CA

After the treatment, one patient saw her first star. Another saw snowflakes for the first time. Other patients were newly able to navigate outside of the home or to read the labels on their child’s Halloween candy. The cause of these seemingly miraculous improvements? A gene therapy developed by...

Gene therapy restores vision in first-ever trial for rare, inherited blindness

Could next-generation gene editing mean a cure for cystic fibrosis (CF)? There's been a lot of advancement on the disease in the last decade, but there are still those living with the disease who get no relief from current treatments - especially those for whom health disparities already exist. Paul...

A cystic fibrosis cure for all? Gene editing shows promise

Investigators involved in a multicenter study co-led by Cedars-Sinai discovered a pathway by which immune cells prevent the lungs’ protective barrier from healing after viral infections like COVID-19. The findings, published in Nature may lead to new therapeutic treatment options. The COVID-19 pandemic revealed how viral infections can cause...

Immune cells prevent lung healing after viral infection

As genetic sequencing technology becomes more accessible and efficient, researchers have made significant strides in understanding the genetic underpinnings of various diseases. This knowledge has led to a surge in clinical applications of genetic testing, offering hope and improved outcomes for individuals affected by many genetic diseases and disorders. Despite these successes, scientists continue to try to improve genetic testing technologies, because many individuals with rare diseases remain undiagnosed even after current state-of-the-art genomic testing.

HudsonAlpha researchers awarded NIH grant to identify genetic contributors to rare diseases in children

Houston, TX

HOUSTON ― The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

MD Anderson research highlights for September 4, 2024

Osaka, Japan – Vaccines work by equipping our immune systems to fight an invading virus. When we get vaccinated against COVID-19, specialized immune cells known as B cells learn to recognize the virus. If we subsequently get infected with COVID, these B cells will quickly manufacture antibodies to attack and destroy the virus. However, because the mRNA vaccines developed for COVID-19 are so new, researchers did not know exactly which B cells were called into action.

Uncovering the specialized immune cells that fight COVID-19

New research shows how oceans can be used to help address major challenges such as the shortage of antimicrobial medicines, solutions for plastic pollution and novel enzymes for genome editing. In the past 20 years, scientists have greatly increased the number of microbial genomes they have collected from the ocean....

Study shows how oceans are key to addressing global challenges

Prof. Christian Gaebler, an HIV researcher at Charité – Universitätsmedizin Berlin, has a goal: to develop treatments that cure HIV infection in patients or prompt the immune system to keep the virus in check in the long term, even without medications. To that end, Gaebler plans to conduct a detailed study of patients who are already living without medication. His research project has now persuaded the European Research Council (ERC), which has awarded him about 1.5 million euros in funding under an ERC Starting Grant.

On a mission to cure HIV: Christian Gaebler receives ERC Starting Grant

Islands drive language change and generate language diversity in similar ways to how they drive species diversity, according to new research from The Australian National University (ANU) that analysed languages from over 13,000 inhabited islands. Although accounting for a tiny proportion of the world’s land mass, islands have had a...

Islands are engines of linguistic diversity, study shows

The American Journal of Gastroenterology has published a new guideline on the treatment of Helicobacter pylori (H. pylori) infection. The corresponding author on the guideline is William D. Chey, M.D., chief of the Division of Gastroenterology and Hepatology at Michigan. H. pylori is a bacterium that infects over half the...

New guideline for Helicobacter pylori includes change to primary treatment recommendation

Dr Michael-John Dolan has won a highly prestigious European Research Council (ERC) Starting Grants to pursue research aimed at uncovering the secrets of brain disorders and repair. Dr Dolan’s project: MICRODISSECT: Dissection of Microglial State Biology in Brain Repair. Dr Dolan’s research will focus on microglia, the brain's resident...

Seeking the secrets to brain repair -- Trinity scientist wins European Research Council Starting Grant

The most frequently used mpox vaccine provides partial immunity to the disease but isn’t always able to prevent severe symptoms or disease transmission. A new vaccine candidate from Moderna, mRNA-1769, more effectively limits symptoms and disease duration in primates that were infected with a lethal strain of the mpox virus when compared to a currently licensed modified vaccinia Ankara (MVA) vaccine. The study publishes September 4 in the Cell Press journal Cell.

Investigational mpox mRNA vaccine reduces disease severity in primates compared to available vaccines

About The Study: Among adults age 60 years and older in 19 U.S. states, respiratory syncytial virus (RSV) vaccination was associated with a reduced likelihood of hospitalization with RSV compared with no vaccination. These findings expand upon prelicensure trial results in 2 ways. First, they provide evidence of vaccine protection against RSV-associated hospitalization, of which an estimated 60,000 to 160,000 occur annually among U.S. adults age 65 years and older. Second, they demonstrate protection in a population that more closely represents those at high risk of severe RSV disease, including adults age 75 years and older and those with immunocompromising conditions.

RSV vaccine effectiveness against hospitalization among US adults 60 years and older

Los Angeles, CA

LOS ANGELES — Oncology specialists at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the United States, can now provide leading-edge clinical guidance to patients living in Southeast Asia through a second opinion collaboration agreement with the Healthway Cancer Care Hospital, the first comprehensive cancer hospital in the Philippines. This strategic integration of services will enhance Southeast Asia’s access to world-class cancer care by leveraging the strengths of both institutions.

City of Hope to offer second opinions for cancer patients in Southeast Asia via a collaboration agreement with the Healthway Cancer Care Hospital

Rice and spinach are staples for babies’ and young children’s diets, but toxic metals and metalloids found in those foods can cause severe health impacts. In particular, heavy metals such as cadmium, lead, mercury, and metalloid arsenic could delay brain development in babies and young children. In new...

Making baby food safer

Chicago, IL

A cellular link between obesity and atrial fibrillation — a heart condition that afflicts over 33 million people worldwide — presents a promising target for new therapies, researchers from the University of Illinois Chicago report. Obesity is among the leading causes of atrial fibrillation, an irregular heart rhythm...

Breaking the link between obesity and atrial fibrillation with a new cellular target

Dallas, TX

In a pioneering new study, researchers made the skin on the skulls and abdomens of live mice transparent by applying to the areas a mixture of water and a common yellow food coloring called tartrazine. Dr. Zihao Ou, assistant professor of physics at The University of Texas at Dallas, is...

Yellow dye solution makes tissue transparent on living animals

Columbus, OH

COLUMBUS, Ohio – About half of adults can identify cigarettes and e-cigarettes, but just one in four would recognize oral nicotine pouches, and these easily available products are growing increasingly popular among teens and young adults, according to a recent study commissioned by The Ohio State University Comprehensive Cancer Center – Arthur G. James Hospital and Richard J. Solove Research Institute (OSUCCC – James).

Can you identify the new threat attracting Gen Z to nicotine use?

Ann Arbor, MI

Vaccination against respiratory syncytial virus for adults over 60 is likely cost-effective by preventing illness, hospitalizations, lost quality of life and deaths, according to new research. The study conducted by researchers at the University of Michigan and the U.S. Centers for Disease Control and Prevention and published in the journal...

New RSV vaccine for older adults can result in individual and societal cost savings, benefits

A new study by investigators from Mass General Brigham has found that obesity may be an important risk factor for infection from the virus that causes COVID-19. Researchers analyzed electronic health record data from Mass General Brigham and found that individuals with obesity were 34% more likely to become COVID positive after reported exposure than individuals without obesity. Their findings, published in PNAS Nexus, indicate that obesity, a well-known risk factor for more severe symptoms and complications from the virus, may also increase risk of infection.

Obesity may increase susceptibility to contracting COVID-19

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NewsBreak

100x improvement in sight seen after gene therapy trial

PHILADELPHIA— The vision of people with a rare inherited condition that causes them to lose much of their sight early in childhood was 100 times better...

100x improvement in sight seen after gene therapy trial

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