Copa America: Colombia vs. Panama odds, picks and predictions

Colombia battles Panama in a Copa America quarterfinal Saturday. Kickoff from State Farm Stadium in Glendale, Ariz., is set for 6 p.m. ET (FS1). Below, we analyze FanDuel Sportsbook’s lines around the Colombia vs. Panama odds, and make our best soccer bets, picks and predictions.

Colombia had a terrific group stage and came into Copa America having dominated its international friendlies. Colombia beat Paraguay 2-1 and Costa Rica 3-0 before drawing Brazil 1-1 in its 3 group stage games. It beat Spain 1-0, Romania 3-2, USA 5-1 and Bolivia 3-0 in its 4 pre-Copa America friendlies. Liverpool F Luis Díaz is the most lethal attacking player for Colombia.

Panama had one of the most high-profile group stage upsets as it beat the USMNT 2-1 June 27. That was Panama’s 2nd group stage match. It kicked off the tournament with a 3-1 loss to Uruguay and closed the stage with a 3-1 win over Bolivia Monday. Panama came into Copa America having played 5 games in 2024, 2 of which were World Cup Qualifiers. In those 5, Panama was 2-0-3.

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Colombia vs. Panama odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:31 a.m. ET.

• Moneyline: Colombia -320 (bet $320 to win $100) | Panama +1000 (bet $1,000 to win $900) | Draw +410 (bet $100 to win $410)
• Over/Under: 2.5 (O: -116 | U: -106)

Colombia vs. Panama picks and predictions

Prediction

Colombia 3, Panama 1

Moneyline (ML)

PASS.

Unfortunately, there’s no good value here. Colombia (-320) is playing like one of the best teams in the tournament, and it should be able to come out on top here with relative ease.

The quality teams — which Colombia is — that Panama has faced in 2024 include Mexico and Uruguay. Those games, both losses, ended a combined 6-1 in favor of Panama’s opponents. Colombia is just a tier (or a few) above Panama. For over 3 times a potential return at -320, Colombia is far too risky to take on the moneyline though.

Over/Under (O/U)

BET OVER 2.5 (-116).

Panama’s backline has been susceptible, and that should continue Saturday. Panama has allowed a combined 5 goals in 3 games. It has gone Over this total in all 3 and in 4 of its last 5 matches. Colombia has gone north of this total in 2 of 3 games, having scored 6 goals in the 3 matches. It went Over this total in the 3 friendlies prior to Copa America as well.

Colombia has Diaz along with a slew of high-quality attacks like Sao Paulo F James Rodriguez. Colombia has also allowed a goal in 2 of 3 games. Expect a high-scoring game given the weak defense Panama has and the lethal Colombia attack.

BACK OVER 2.5 (-116).

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