Review of: Risk of nonarteritic anterior ischemic optic neuropathy in patients prescribed semaglutide. Hathaway J, Sha M, Hathaway D, et al. JAMA Ophthalmology, in press 2024. Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA) prescribed to assist with weight management in patients with type 2 diabetes (T2D) or those who are overweight/obese, and there have been anecdotal reports of nonarteritic anterior ischemic optic neuropathy (NAION) in patients taking this medication. This single-center, observational study compared patients prescribed semaglutide to matched patients prescribed other medications for diabetes and found a greater risk of NAION in the semaglutide cohort, though additional studies are needed to verify this relationship and causality cannot be inferred.

Semaglutide May Be Associated With an Increased Risk of Developing NAION

The Marijuana Herald

The Marijuana Herald - Marijuana news and information
According to a study published in the Archives of Medical Sciences: Atherosclerotic Disease, heart attack patients with a history of marijuana use have a lower in-hospital mortality rate compared to those without a history of use. For the study, researchers from various institutions, including the Detroit Medical Center-Wayne State University and the Royal Devon University … 
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Study of Nearly 10 Million People Finds Marijuana Linked to Improved Outcomes for Heart Attack Patients, Reduced In-Hospital Mortality

Combination therapy with ezetimibe led to a greater reduction in LDL-C levels than statin monotherapy, but no significant effect on MACE outcomes. Adding ezetimibe to low- or moderate-intensity statins led to a higher reduction in low-density lipoprotein cholesterol (LDL-C) than high-intensity statin monotherapy in patients with existing atherosclerotic cardiovascular disease (ASCVD), according to the results of a systematic review and meta-analysis.1.

Combination Ezetimibe, Statin Therapy Superior in Reducing LDL-C Levels

As of 2020, about 17.6 million people worldwide have the autoimmune disease rheumatoid arthritis. Past studies have linked rheumatoid arthritis to an increased risk for a number of health concerns. Researchers from the University of Málaga in Spain have now linked rheumatoid arthritis to a greater chance of developing specific...

Why is rheumatoid arthritis tied to a higher risk of cognitive decline?

Scientists from Mayo Clinic and Yale University used organoids, or mini-brain models, to study the development of autism spectrum disorder (ASD). They discovered an imbalance in excitatory cortical neurons, which are crucial for brain communication and function. By analyzing gene expression in these neurons, they identified changes in transcription factors that may underlie ASD. The research highlights the potential of using organoids to understand brain disorders and possibly prevent ASD through prenatal genetic testing.

Unlocking Autism: Mayo Clinic’s “Mini-Brain” Study Reveals Key Insights

Productivity improved in patients with IA after starting treatment. Inflammatory arthritis (IA) and osteoarthritis (OA) cause a substantial loss in productivity during the year before and after diagnosis. IA treatment seems to improve productivity.1. “Work disability can manifest as reduced productivity at work (presenteeism), absence from work (absenteeism), and, eventually,...

Inflammatory, Osteoarthritis Cause Substantial Loss in Productivity

Philadelphia, August 20, 2024 – According to new research, cognitive impairments in psychotic disorders, such as schizophrenia and bipolar disorder, are linked to brain network organization. This link between cognition and brain networks is present in individuals considered at-risk for psychotic disorders even prior to their first psychotic break. This groundbreaking study in Biological Psychiatry, published by Elsevier, suggests an opportunity for early diagnosis and intervention for these treatment-resistant symptoms.

Groundbreaking study shows promise for early detection and intervention in psychotic disorders such as schizophrenia

South Carolina State

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Explore Beaufort SC

The mantis shrimp is one tough customer. Beautiful and deadly are two words you don’t typically use to describe shrimp, but the mantis shrimp is definitely in a class of its own; earning a reputation as the ‘savage boxer of the sea’ and one of the most fearsome creatures in the ocean. And, they're right at home here in South Carolina.

Savage Boxer of the Sea: The Deadly Beauty of Mantis Shrimp

An abnormal buildup of fat in the liver, referred to as fatty liver disease, was found to be common in a small group of children and adults with spinal muscular atrophy (SMA), regardless of their disease type or severity. Patient-derived liver cells confirmed that such accumulation was a result of...

Fatty liver disease may be common complication of SMA: Small study

Medical News Today

A recent study has found an association between severe menopause symptoms and mild cognitive impairment, calling for further research on this topic.

Severe menopause symptoms linked to mild cognitive impairment

Los Angeles, CA

Herbie J Pilato

Adam Rich was born on October 12, 1968, lived a troubled life, and died on January 7, 2023, at only 54 years old. This is his story. He lived in the Granada Hills area of Los Angeles with his parents and younger brother. The Rich family resided for a time in Florida where Adam studied acting at the local gym.

A Look Back at the Tragic Life and Death of Former Child Star Adam Rich (TV's 'Eight is Enough')

Colorado State

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David Heitz

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

Virginia State

Kentucky Vibes.net

Disclaimer: This article was written with the help of A.I. software. On July 28, 2024, a TikTok video posted by Erica W., known as @tasteofmelanin on the platform, garnered significant attention after she exposed disturbing racist decorations in an Airbnb rental. The incident occurred in a rental property that Erica had booked, although the exact location remains unspecified. The video has since gone viral, prompting widespread concern and leading to the removal of the listing from Airbnb's platform.

Airbnb Listing Taken Down After Black Woman Finds Hanging Monkeys and Cotton Used As Decor

In 2024, kidney cancer is projected to be one of the top 10 cancers in terms of incidence rate in the United States, with an estimated 81,610 new diagnoses. In 2024, kidney cancer is projected to be one of the top 10 cancers in terms of incidence rate in the United States, with an estimated 81,610 new diagnoses.1 with an estimated 81,610 new diagnoses. Renal cell carcinoma (RCC) accounts for approximately 80% to 90% of all kidney cancer cases, with the predominant subtype being clear cell RCC (ccRCC).2.

From Bench to Bedside: HIF-2α Inhibition in RCC

Structural features tracked on brain MR imaging after patients undergo stereotactic radiotherapy (SRT) for metastatic cancer can help clinicians predict whether tumors will recur, according to a study published August 20 in Cancer Imaging. The findings could improve the management of patients with brain metastases, wrote a team led by...

Brain MRI helps predict tumor recurrence after SRT

A new study found that older patients with atrial functional mitral regurgitation who underwent mitral valve surgery had significantly better outcomes than those who received medical management alone, including lower rates of heart failure hospitalization and death. Patients with atrial functional mitral regurgitation (AFMR) who undergo mitral valve (MV) surgery...

Surgery Improves Outcomes for Patients With Atrial Functional Mitral Regurgitation

Research on over 24,000 men revealed that low testosterone levels significantly increase the risks of death from all causes and cardiovascular issues, underlining the hormone’s impact on aging men’s health. A systematic review and meta-analysis revealed that men with low baseline levels of endogenous serum testosterone face a...

Low Testosterone in Men Linked to Increased Risk for Death

The following is a summary of “Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients,” published in the August 2024 issue of Hematology by Halik et al. Researchers conducted a retrospective study to characterize the genomic landscape and prognostic implications of chromosome...

Investigating the Role of TP53 and KMT2C Mutations in AML with Chromosome 7 Deletions

Apache Junction, AZ

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Suzy Jacobson Cherry

When I studied Anthropology in college, I learned that teeth have been indicators of economic status just about forever. Archaeologists look at the teeth in ancient skeletons and know who the rich were based on their tooth decay. During the Renaissance period, it became fashionable for women to blacken their teeth to look like they were better off than they were, because the royals and aristocrats, who could afford sugar and sweets, had more rotten and missing teeth than the poor.

Opinion: Stop Stereotyping Bad Teeth as a Sign of Drug Addiction

Researchers from the University of Missouri discovered that targeting the ERBB2 gene in mice with PTEN mutations significantly slowed endometrial cancer growth. This finding offers hope for alternative treatments beyond hysterectomy and aggressive therapies, particularly for women concerned with fertility preservation and early-stage cancer management. Key Takeaways. Targeting the ERBB2...

New Targeted Therapy Shows Promise in Slowing Endometrial Cancer Growth

NewsBreak

IMPACT-FH: Cascade Strategies Improve Testing for Familial Hypercholesterolemia

Cascade testing strategies significantly increased the detection of FH, with direct contact yielding a 16-fold higher testing rate, according to the IMPACT-FH study. Results of the...

IMPACT-FH: Cascade Strategies Improve Testing for Familial Hypercholesterolemia

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