Topline results from the Phase III V-MONO study of Leqvio found that twice-yearly Leqvio achieved clinically LDL-C lowering compared to both placebo and ezetimibe. Results from the Phase III V-MONO trial found that Novartis’ Leqvio (inclisiran) demonstrated noteworthy LDL-C reduction as a monotherapy in patients at low to moderate risk of atherosclerotic cardiovascular disease (ASCVD). According to the company, this is the first study to evaluate a small interfering RNA (siRNA) therapy for LDL-C reduction in this patient population. Additionally, results indicated that twice-yearly Leqvio achieved clinically meaningful and statistically significant LDL-C lowering compared to both placebo and ezetimibe in patients not on other lipid-lowering therapies.1.

Leqvio Demonstrates Significant LDL-C Reduction in Patients at Risk of Atherosclerotic Cardiovascular Disease

UPI News

An experimental genetic test can gauge a person's risk of developing potentially deadly blood clots, researchers report.

New 'platelet score' being used to gauge risk of stroke, heart attack

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Shin

Statins are widely recognized for their role in lowering low-density lipoprotein (LDL) cholesterol and reducing the risk of heart disease. But new research from the Cholesterol Treatment Trialists’ Collaboration (CTSU) has revealed that these life-saving medications may come with a small but significant drawback—an increased risk of developing diabetes, particularly in individuals already predisposed to the condition.

Statins and Diabetes: New Comprehensive Research Confirms Elevated Risk

Everyday Health

Fatigue, feeling dizzy or out of breath, and headaches are some of the most common signs of anemia, a blood disorder in which the body lacks sufficient levels of red blood cells.

12 Most Common Symptoms of Iron-Deficiency Anemia

There are tens of millions of people in the U.S. taking the cholesterol-lowering medications known as statins to prevent heart disease. This could be because the U.S. Preventative Services Task Force advises healthcare professionals to prescribe statins in patients ages 40 to 75 who have at least one risk factor for heart disease, such as diabetes or dyslipidemia, and an estimated 10-year cardiovascular risk of 10 percent or more.

Glaucoma joins growing list of statin side effects

shefinds

Supplements are often taken to improve health and fill nutritional gaps, but not all are as beneficial as they seem. Some supplements, particularly when taken in excess or without proper guidance, can have unintended negative effects. For example, certain supplements can unknowingly contribute to high blood pressure and increase the risk of cardiovascular events.

4 Worst Supplements That Could Actually Lead To High Blood Pressure And Cardiovascular Events: Licorice Root & More

In the United States, approximately 47% of adults have hypertension, a condition characterized by consistently elevated blood pressure. This statistic is concerning as high blood pressure is a significant risk factor for serious health issues, including heart disease, stroke, and kidney disease. Elevated blood pressure often goes unnoticed due to its asymptomatic nature, earning it the nickname “the silent killer.” Health practitioners must prioritize blood pressure monitoring and management, as early detection and treatment can prevent complications and improve overall health outcomes. By addressing hypertension, practitioners can significantly reduce the burden of cardiovascular diseases and enhance the quality of life for their patients.

9 Effective Ways to Lower Blood Pressure Naturally

Older adults with diabetes are at a higher risk of developing Alzheimer’s disease and other forms of dementia. New research suggests that blood sugar stability, measured by HbA1c time in range (TIR), might provide better insights into this risk than traditional HbA1c levels. The study found that veterans with...

Type 2 diabetes: Stable A1C levels may be linked to lower dementia risk

Hypoglycemia symptoms include having anxiety, emotional instability, dizziness, and lightheadedness. Here's a list with more signs to watch for.

10 Warning Signs of Low Blood Sugar

An anti-inflammatory diet reduced the risk of dementia by 31% in people even if they had type 2 diabetes, heart disease or stroke, according to a new study.

Eating these foods lowers dementia risk, even with type 2 diabetes and heart disease, study says

Evidence suggests chronic pain can affect the mechanism that regulates blood pressure, causing blood pressure to become too high. High blood pressure, also known as hypertension, is when the pressure inside the blood vessels is consistently too high. Pain and hypertension often occur together. Blood pressure and pain. As a.

Can pain cause high blood pressure?

A genetics-based platelet reactivity score can help identify people with a hyperreactive platelet phenotype who may have increased risk for a cardiovascular event, according to research published in Nature Communications. In two high-risk cohorts, researchers reported an association between an above-median Platelet Reactivity Expression Score (PRESS) and increased risk for...

Top in cardiology: Platelet score predicts heart trouble; chronic noise and hypertension

An abnormal buildup of fat in the liver, referred to as fatty liver disease, was found to be common in a small group of children and adults with spinal muscular atrophy (SMA), regardless of their disease type or severity. Patient-derived liver cells confirmed that such accumulation was a result of...

Fatty liver disease may be common complication of SMA: Small study

High cholesterol can cause the arteries to narrow, leading to serious complications, such as heart disease, heart attack, and stroke. Lowering high cholesterol can help prevent complications. High cholesterol can lead to excess cholesterol in the blood, which can cause a buildup of fatty deposits, or plaque, in the arteries.

Potential complications of high cholesterol

DogTime

Familial kidney disease is an umbrella term used to describe various genetically transmitted conditions that impair the normal function of a dog’s kidneys. Unlike some hereditary kidney diseases, which have a clearly identified genetic basis and mode of inheritance, most familial kidney diseases are characterized by their frequent occurrence within certain dog families without a […]
The post Familial Kidney Disease in Dogs: Symptoms, Causes, & Treatments appeared first on DogTime.

Familial Kidney Disease in Dogs: Symptoms, Causes, & Treatments

What treatments are available for management of pain and other fibromyalgia-related symptoms?. What do we know about efficacy of antidepressants, including SNRIs, in management of pain and other fibromyalgia symptoms?

Treatment option for fibromyalgia

Dehydration affects 20% to 30% of older adults and is usually caused by insufficient water intake. It may also be caused by excess water loss through diarrhea, vomiting, sweating, high fever, or side effects from medication. Dehydration occurs when a person loses more water than they take in. Water serves...

Symptoms of Dehydration in Adults Older Than 65

Pittsburgh, PA

Allegheny Health Network (AHN) implants innovative device to manage central sleep apnea in heart failure patients, reducing mortality rise and improving quality of life. Teams from the AHN Sleep Medicine Center and the AHN Cardiovascular Institute implanted remedē®, a pacemaker-like device that works to restore restful sleep for adult patients living with CSA. It stimulates normal breathing rhythms with small electrical currents to the diaphragm and can mitigate the need for continuous positive airway pressure (CPAP) systems and the masks that come with them.

AHN implants innovative device to manage central sleep apnea in heart failure patients

This is the third installment of a 6-part series on the lifelong journey of polycystic ovarian syndrome (PCOS) and the stops along the way that a female may face. In this installment, Danielle R. Stratton, DNP, RN, PPCNP-BC, will discuss insulin resistance and diabetes and the significant impact it can have on a female with the syndrome on her health and the impact on her entire body systems, and her health’s future as we continue with this series.

Polycystic Ovarian Syndrome: Insulin Resistance and Diabetes Mellitus

FDA expands Omnipod 5 AID system for type 2 diabetes, marking the first AID system approved for both type 1 and type 2 diabetes management. The US Food and Drug Administration (FDA) has announced the expansion of indications for Insulet Corporation’s SmartAdjust technology, clearing the way for use of the Omnipod 5 Automated Insulin Delivery (AID) System in adults with type 2 diabetes.1.

FDA Clears Omnipod 5 AID System for Type 2 Diabetes

NewsBreak

Patients With Hospitalized IBD and RA Have Higher Cardiovascular, Kidney Injury Risk

Lengths of stay, total cost, and hospital mortality rates were similar between patients with and without rheumatoid arthritis. Patients hospitalized with irritable bowel disease (IBD) with...

Patients With Hospitalized IBD and RA Have Higher Cardiovascular, Kidney Injury Risk

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