Columbus, OH

Metformin, a medication commonly used to treat type 2 diabetes, helps the body regulate sugar in the bloodstream. Part of the class of drugs known as biguanides, metformin reduces the amount of sugar you absorb from food and the amount produced by the liver. Metformin also impacts the way the body will respond to insulin, the natural substance that regulates blood sugar levels.

Diabetes Drug Metformin Investigated for Cancer Prevention Use

Factors such as age, sex, and family history can impact a person’s risk of getting pancreatic cancer. It is more likely to occur later in life. Certain conditions can also increase the likelihood of pancreatic cancer. Pancreatic cancer develops in the tissues of the pancreas. This organ secretes digestive...

Who is most likely to get pancreatic cancer?

Atherosclerotic cardiovascular disease is linked to plaque buildup in blood vessels. It can increase the risk of serious cardiovascular events, such heart attack and stroke. Statins are a medication type that can help people at risk for atherosclerotic cardiovascular disease. Doctors look at several factors to determine if statin therapy makes the most sense for someone.

17 million US adults may no longer receive statin therapy for heart disease

rolling out

Pancreatic cancer is a daunting diagnosis that affects thousands of people worldwide every year. One of the most challenging aspects of this disease is its subtlety; the symptoms often mimic those of other, less severe conditions. This similarity can lead to delayed diagnosis and treatment, significantly impacting the prognosis. Understanding why pancreatic cancer symptoms resemble other diseases’ symptoms is crucial for early detection and better outcomes. This article will delve into the reasons behind this symptom overlap, explore common symptoms of pancreatic cancer, and provide insights on differentiating these symptoms from other ailments.

Why pancreatic cancer symptoms are similar to other diseases

June 27, 2024 – If you’re taking a statin drug to prevent heart disease, it’s possible that, sometime in the next year or two, your doctor might tell you that it’s no longer necessary. If and when that change happens, it will reflect the use of...

Many People on Statins May Not Need Them

Deep vein thrombosis (DVT) occurs when a blood clot forms in a deep vein, typically in the legs. Treating a DVT is crucial, as the clot can break loose from the affected vein, move through the bloodstream to the heart, and lodge itself within the lung's main artery. This complication—what's known as pulmonary embolism—can be fatal.

How to Dissolve Blood Clots in Legs

Review the multiple uses of metformin. A recent article on the multiple uses of metformin brings up the important topic of repurposing medications.1 Repurposing has been around since the advent of modern medicine. One prominent example is the use of chlorpromazine (CPZ) as an antipsychotic.2 Chlorpromazine was first synthesized in 1951 as a potentiator of general anesthesia.2 The psychiatric benefits were found later by Henri Laborit, a surgeon in the French army. He was doing research with artificial hibernation in prevention of surgical shock.2 Laborit employed the drug as an adjunct to anesthetics.2 He observed that CPZ at doses of 50 mg to 100 mg produced a lowering of body temperature, sedation, and disinterest without loss of consciousness.2 He was able to persuade his colleagues in the military hospital in Paris to try CPZ in the treatment of one of their patients who was experiencing psychotic agitation.2 Laborit hypothesized that since cooling with water had been used to treat agitation in France, the drug would have a similar effect.2 The mechanism of action was not fully known, and it was thought that it worked in controlling agitation because of its cooling effect and induction of “artificial hibernation” in patients.2 The pharmacological mechanism was not fully understood until many years later and the way it has impacted the practice of psychiatry needs no introduction. These “happy accidents” in medicine have played a vital role in getting where we are right now compared with just 50 years ago. This begs the question, are we onto another “happy accident” with metformin? There is an accumulating body of evidence that metformin may have benefits in aging that are beyond its effect on glycemic control.3.

Metformin, Inflammation, the Gut Microbiome, and Health Span: Connecting the Dots

The Motley Fool

A lot of people love Target. But here's why it may be time to say goodbye.

Here's Why You May Never Want to Set Foot in Target Again

The spice turmeric is a popular food supplement due to a molecule it contains called curcumin, which acts as a strong antioxidant. it is also thought that it could be used to treat or prevent inflammatory conditions. Turmeric’s use has grown in popularity in the past decade or two, with...

Turmeric and black pepper supplements linked to liver injury in some people

Metabolic dysfunction-associated steatotic liver disease (MASLD)—the new name for non-alcoholic fatty liver disease (NAFLD)—and its more severe form, metabolic dysfunction-associated steatohepatitis (MASH), are responsible for a growing share of advanced liver disease. Linked to obesity and diabetes, fatty liver disease is increasingly recognized as a metabolic condition. Over...

Treatment for Fatty Liver Disease

Research findings show that pitavastatin suppresses skin and pancreatic cancers by inhibiting interleukin-33. A recent study conducted by researchers at Mass General Cancer Center has found that statins, which are widely used to reduce cholesterol, might inhibit a specific pathway linked to cancer development caused by chronic inflammation. These results were reported in Nature Communications.

Groundbreaking New Study Reveals That Statins Could Prevent Cancer

Everyday Health

New research suggests statins may reduce heart disease risk and increase longevity in adults 75 and older, challenging current guidelines.

Statins Reduce Heart Disease Risk in Adults Age 75 and Up

The signs that thyroid cancer has spread can vary depending on where in the body it has traveled to. Thyroid cancers often spread to the nearby lymph nodes and the lungs, bone, brain, and liver. For all types of thyroid cancer, early detection and personalized treatment plans are crucial for...

What are some signs that thyroid cancer has spread?

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Total Apex Sports & Entertainment

What does it mean to be selfish? According to the Merriam-Webster dictionary, the definition of selfish is the lack of consideration for others; someone concerned chiefly with one's own personal profit or pleasure. You know, people who will do for themselves before they will do for others. People who put their own priorities above everyone else. Do you know people who fit that definition? I am sure we all know at least one, I have known man over the years. Let’s learn what Signs are the most likely to be selfish.

The Top 5 Most Selfish Zodiac Signs

Specific zodiac signs in astrology are viewed as homebodies due to the natural traits associated with their astrological profiles. These traits influence their preferences and comfort zones. The homebody tendencies of these zodiac signs develop out of their internal need for comfort, security, and personal space.

4 Zodiac Signs Who Love Staying In

Newark, NJ

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Morristown Minute

NEWARK, N.J. – Eight individuals associated with the "793 Bloods" street gang, a subset of the national Bloods gang, have been charged for their roles in a Newark-based drug trafficking organization, U.S. Attorney Philip R. Sellinger announced.

Eight '793 Bloods' Gang Members Charged in Newark Drug Network

A new study showed that the active ingredient in Ozempic and Wegovy can help these patients slash their risk of complications and death.

Ozempic and Wegovy Slash Kidney Disease Risks in People With Diabetes

If you are living with diabetes, you may already know you are at higher risk for cardiovascular disease, including heart attack, heart failure, and stroke. According to the Centers for Disease Control and Prevention (CDC), people who have diabetes are twice as likely to have cardiovascular disease. What you may not know is that it is important for someone with diabetes to maintain low LDL cholesterol because your blood LDL cholesterol level is a contributing factor to cardiovascular disease.

Statins: A Powerful Ally for People Living with Diabetes

Marriage is considered the most sacred phase of a relationship. Not everybody is blessed to have a lasting partner committed to marriage. But do you know this trait can most likely be found through their zodiac sign? That's true. Zodiac signs play a pivotal role in deciding a person's traits, including their willingness to marry.

4 Zodiac Signs Most Likely to Embrace the Joys of Marriage

Healthline

IBD and endometriosis can result in similar symptoms, such as severe abdominal pain. However, further research is still needed to confirm a link.

IBD and Endometriosis: Is There a Link?

NewsBreak

Can statins help prevent cancer? New study offers clues

Statin medications help keep cholesterol levels within a healthy range, but researchers are interested in other uses for these medications. Inflammation is one risk factor for...

Can statins help prevent cancer? New study offers clues

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