A major cause of inflammatory bowel disease (IBD) has been discovered by UK scientists. They found a weak spot in our DNA that is present in 95% of people with the disease. It makes it much easier for some immune cells to go haywire and drive excessive inflammation in the bowels.

Major cause of inflammatory bowel disease found

Health

Reviewed by Ivy Kwong, LMFTReviewed by Ivy Kwong, LMFTIrritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) are two chronic gastrointestinal disorders that share some overlapping symptoms, like abdominal pain, bloating, and diarrhea. While IBS and IBD have similar symptoms and acronyms, they are two distinct conditions with different underlying causes and treatment approaches. IBS is a functional disorder, meaning it affects how the intestines work but doesn't cause inflammation. IBD is an inflammatory disease that damages the gastrointestinal (GI) tract. In the United States, IBS affects between 25-45 million people, and IBD affects more than 3 million people.Symptoms of IBS vs....

What Is the Difference Between Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD)?

San Diego, CA

Engineers at the University of California San Diego have developed a pill that releases microscopic robots, or microrobots, into the colon to treat inflammatory bowel disease (IBD). The experimental treatment, given orally, has shown success in mice. It significantly reduced IBD symptoms and promoted the healing of damaged colon tissue without causing toxic side effects.

Microrobot-packed pill shows promise for treating inflammatory bowel disease in mice

Restless leg syndrome (RLS) is a frustrating condition that affects as much as ten percent of the U.S. population, especially women and older adults. The symptoms often come at the worst possible time: at night, when you’re trying to sleep. It starts with a throbbing, itching or uncomfortable sensation...

Genetic study dives into restless leg syndrome

Some weird signs of iron deficiency include developing a craving for ice or clay, an overwhelming urge to move the legs, and hair loss. However, iron deficiency can cause a range of symptoms. Iron deficiency describes when a person does not have enough iron in their body. When iron levels...

5 weird signs of iron deficiency

Understanding your bowel movements is crucial for maintaining overall health. Your colon, also known as the large intestine, plays a significant role in your digestive system. Constipation and other changes in bowel movements can be indicators of your colon’s health. In this article, we’ll explore what these signs mean and how you can maintain a healthy colon.

What constipation and bowel movements tell you about your colon

While complementary therapies won’t treat the underlying cause of ulcerative colitis (UC), they can help you manage your symptoms and improve your overall quality of life. Ulcerative colitis (UC) is one of two main types of inflammatory bowel disease (IBD), the other being Crohn’s disease. UC causes inflammation and open sores on the colon’s inner linings.

Complementary Care Toolkit for Ulcerative Colitis

Review the multiple uses of metformin. A recent article on the multiple uses of metformin brings up the important topic of repurposing medications.1 Repurposing has been around since the advent of modern medicine. One prominent example is the use of chlorpromazine (CPZ) as an antipsychotic.2 Chlorpromazine was first synthesized in 1951 as a potentiator of general anesthesia.2 The psychiatric benefits were found later by Henri Laborit, a surgeon in the French army. He was doing research with artificial hibernation in prevention of surgical shock.2 Laborit employed the drug as an adjunct to anesthetics.2 He observed that CPZ at doses of 50 mg to 100 mg produced a lowering of body temperature, sedation, and disinterest without loss of consciousness.2 He was able to persuade his colleagues in the military hospital in Paris to try CPZ in the treatment of one of their patients who was experiencing psychotic agitation.2 Laborit hypothesized that since cooling with water had been used to treat agitation in France, the drug would have a similar effect.2 The mechanism of action was not fully known, and it was thought that it worked in controlling agitation because of its cooling effect and induction of “artificial hibernation” in patients.2 The pharmacological mechanism was not fully understood until many years later and the way it has impacted the practice of psychiatry needs no introduction. These “happy accidents” in medicine have played a vital role in getting where we are right now compared with just 50 years ago. This begs the question, are we onto another “happy accident” with metformin? There is an accumulating body of evidence that metformin may have benefits in aging that are beyond its effect on glycemic control.3.

Metformin, Inflammation, the Gut Microbiome, and Health Span: Connecting the Dots

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Total Apex Sports & Entertainment

People have different levels of maturity. An individual’s age or upbringing can make them possess certain traits. Yet, most people believe that one matures as they grow old. On the contrary, some zodiac signs appear childish in old age. They are jumpy and careless. This strains their relationships with signs who misunderstand them. Air and fire signs are temperamental and some people refer to them as being childish. How can you identify an immature sign?

3 Zodiac Signs Who Are Immature

Anxiety may affect digestion and the speed at which food travels through the bowels. This can lead to changes in bowel movements and gastrointestinal symptoms, such as chronic diarrhea and constipation. There is a connection between the gut and the brain, which means changes in mental state can affect the...

How can anxiety affect bowel movements?

A colonoscopy is one of the most important tests doctors use to diagnose Crohn’s disease. It can help them detect signs of Crohn’s, like ulcers, fistulas, or skip lesions. Crohn’s disease is an inflammatory condition that affects your gastrointestinal tract, most often the intestines (bowels). To diagnose...

What Does Crohn’s Disease Look Like on a Colonoscopy?

The spice turmeric is a popular food supplement due to a molecule it contains called curcumin, which acts as a strong antioxidant. it is also thought that it could be used to treat or prevent inflammatory conditions. Turmeric’s use has grown in popularity in the past decade or two, with...

Turmeric and black pepper supplements linked to liver injury in some people

A recent preclinical study found that supplementation with a branded pomegranate extract called Pomanox, from Euromed, may support liver health and alleviate fructose-induced metabolic impairment. A recent preclinical study1 found that supplementation with a branded pomegranate extract (Pomanox from Euromed based in Mollet del Vallès, Spain) may support liver health...

Animal study finds that branded pomegranate extract may alleviate the impacts of fructose consumption on liver metabolism

Approval of Skyrizi marks the first IL-23 specific inhibitor approved for both ulcerative colitis and Crohn disease of similar severity, according to AbbVie. The FDA has approved AbbVie’s Skyrizi (risankizumab-rzaa) for the treatment for adults with moderately to severely active ulcerative colitis (UC). According to the company, this approval makes Skyrizi the first IL-23 specific inhibitor to be approved for both UC and Crohn disease classified as moderate-to-severe. The approval was based on results from the INSPIRE Induction study and the COMMAND Maintenance study. In addition to the approved indications for UC and Crohn disease, Skyrizi also has been approved for active psoriatic arthritis and plaque psoriasis.1.

FDA Approves AbbVie’s Skyrizi for the Treatment of Adults with Moderate to Severely Active Ulcerative Colitis

Medically reviewed by Doru Paul, MDMedically reviewed by Doru Paul, MDGlioblastoma (GBM), also called glioblastoma multiforme, is an aggressive type of brain cancer. While the cancer does not usually spread to other parts of the body, it can quickly spread to other areas of the brain. As the tumor puts pressure on the brain, you can develop a variety of symptoms.Some glioblastoma symptoms, like headache and nausea, are common in all types of brain cancers. These symptoms are known as generalized symptoms. Other symptoms—and how severe they are—can depend on where the tumor is and how big it is. These...

Signs and Symptoms of Glioblastoma (GBM)

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Contributors represent independent, third-party users who have joined our contributor program and self-verified their accounts. They have also demonstrated their experience writing hard news for other outlets. Contributors are expected, like all users, to adhere to our Community Standards.

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Alameda Post

California regulators just stopped AT&T from pulling the plug. California’s Public Utilities Commission on June 20 rejected AT&T’s application to stop providing landlines and other services in areas where there is no other option.

Still Need Your Landline?

EPI has a range of causes, some of which are autoimmune conditions. Treating these underlying conditions can help resolve symptoms of EPI and reduce your risk of complications. Exocrine pancreatic insufficiency (EPI) happens when your pancreas doesn’t have enough digestive enzymes, making it hard for your body to extract nutrients...

Is EPI an Autoimmune Disease?

Pernicious anemia is an autoimmune condition in which the body cannot absorb vitamin B12 properly. A person with pernicious anemia requires lifelong vitamin B12 supplementation. Vitamin B12 is essential for various bodily processes, including the ability to think, produce energy, and keep the nervous system functioning. Pernicious anemia can lead...

What vitamin do people with pernicious anemia need?

A new study from Austria has uncovered a direct connection between specific gut bacteria and food addiction in both mice and humans. The research, published in the journal Gut, offers new insights into the complex relationship between gut microbiota and eating disorders. Researchers from an international team, led by Professor...

Gut Bacteria Linked to Food Addiction: New Hope for Obesity Treatment

Medically reviewed by Smita Patel, DOMedically reviewed by Smita Patel, DOPOEMS syndrome is a very rare multisystem condition where the body's immune system attacks cells in the nervous system. This attack from the immune system is caused by an abnormal immune response to a cancerous tumor.POEMS syndrome symptoms include weakness of the arms and legs, darkening of the skin, and an abnormal increase in the size of lymph nodes and internal organs like the spleen or liver.POEMS syndrome is a chronic (long-term) disorder with no cure. In the United States, POEMS syndrome affects approximately 5,000 people. The disease occurs 1.5...

POEMS Syndrome

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Scientists find new major cause of inflammatory bowel disease

New research has elucidated how an already identified area of the genome contributes to the development of a number of autoimmune or inflammatory diseases, including inflammatory...

Scientists find new major cause of inflammatory bowel disease

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