A major cause of inflammatory bowel disease (IBD) has been discovered by UK scientists. They found a weak spot in our DNA that is present in 95% of people with the disease. It makes it much easier for some immune cells to go haywire and drive excessive inflammation in the bowels.

Major cause of inflammatory bowel disease found

San Diego, CA

Researchers at the University of California San Diego discovered that an unusually large brain could be the first sign of autism, potentially detectable in as early as the first trimester. Some children with autism face severe, enduring challenges including developmental delays, social difficulties, and possibly an inability to speak. Meanwhile,...

Scientists May Have Discovered the First Sign of Autism: An Unusually Large Brain

Review the multiple uses of metformin. A recent article on the multiple uses of metformin brings up the important topic of repurposing medications.1 Repurposing has been around since the advent of modern medicine. One prominent example is the use of chlorpromazine (CPZ) as an antipsychotic.2 Chlorpromazine was first synthesized in 1951 as a potentiator of general anesthesia.2 The psychiatric benefits were found later by Henri Laborit, a surgeon in the French army. He was doing research with artificial hibernation in prevention of surgical shock.2 Laborit employed the drug as an adjunct to anesthetics.2 He observed that CPZ at doses of 50 mg to 100 mg produced a lowering of body temperature, sedation, and disinterest without loss of consciousness.2 He was able to persuade his colleagues in the military hospital in Paris to try CPZ in the treatment of one of their patients who was experiencing psychotic agitation.2 Laborit hypothesized that since cooling with water had been used to treat agitation in France, the drug would have a similar effect.2 The mechanism of action was not fully known, and it was thought that it worked in controlling agitation because of its cooling effect and induction of “artificial hibernation” in patients.2 The pharmacological mechanism was not fully understood until many years later and the way it has impacted the practice of psychiatry needs no introduction. These “happy accidents” in medicine have played a vital role in getting where we are right now compared with just 50 years ago. This begs the question, are we onto another “happy accident” with metformin? There is an accumulating body of evidence that metformin may have benefits in aging that are beyond its effect on glycemic control.3.

Metformin, Inflammation, the Gut Microbiome, and Health Span: Connecting the Dots

Medical News Today

Researchers have successfully reversed the symptoms of Alzheimer’s disease in mice with a small, synthetic peptide called PHDP5.

Peptide treatment could reverse cognitive decline in Alzheimer's disease

A recent study has discovered that omega-3 fatty acids can significantly reduce symptoms of depression and anxiety in young mice subjected to stress, with the mice exhibiting both behavioral and molecular changes. This finding, published in Neurobiology of Stress, offers hope for new treatments for adolescent depression in humans. Major...

Behavioral and molecular changes in mice suggest omega-3 fatty acids could combat depression

The US Sun

MELANIA Trump was nowhere to be found at the 2024 Presidential Debate, adding to rumors of her and Donald’s relationship being on the decline. In a move that broke tradition, the former first lady was notably absent after Donald Trump was seen arriving alone in Atlanta, Georgia for his debate against President Joe Biden on […]

Melania Trump broke a major debate tradition while Jill Biden forced to run to comfort Joe after his cringe performance

Vitamin B12 deficiency is common. It can lead to various health issues, affecting everything from energy levels to brain function. Vitamin B12, or cobalamin, is an essential nutrient in meat, fish, and dairy products. It is crucial for red blood cell production and a healthy nervous system. When B12 levels...

Unusual symptoms of B12 deficiency

West Virginia State

Kanawha County, WV

Two West Virginia parents are awaiting trial on more than a dozen charges after adopting four Black children and allegedly using them for “forced labor” on their farm, court documents show.

West Virginia couple charged with trafficking their adopted Black children to be used as ‘slaves,’ authorities allege

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NewSantaAna

The FBI has seen a rise in scams targeting timeshare owners. In this kind of scam, criminals con these part-time property owners into shelling out hefty sums of cash, all under false pretenses related to their timeshare properties.

FBI warns that Mexican cartels are targeting Americans with timeshare scams

The spice turmeric is a popular food supplement due to a molecule it contains called curcumin, which acts as a strong antioxidant. it is also thought that it could be used to treat or prevent inflammatory conditions. Turmeric’s use has grown in popularity in the past decade or two, with...

Turmeric and black pepper supplements linked to liver injury in some people

A recent preclinical study found that supplementation with a branded pomegranate extract called Pomanox, from Euromed, may support liver health and alleviate fructose-induced metabolic impairment. A recent preclinical study1 found that supplementation with a branded pomegranate extract (Pomanox from Euromed based in Mollet del Vallès, Spain) may support liver health...

Animal study finds that branded pomegranate extract may alleviate the impacts of fructose consumption on liver metabolism

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Total Apex Sports & Entertainment

Do you know anyone who has dual nature? Such two-faced zodiac signs are friendly but they gossip about others behind their backs. They can lie to you without batting an eyelid. However, detecting a two-faced person isn’t easy for everyone. They often compliment their friends when they achieve a goal or change their wardrobe. But they will make negative remarks about you to someone else. What other traits do two-faced people have?

3 Zodiac Signs Who Are Two-Faced

The Mirror US

Menthol, an extract from mint herbs, could improve cognition, including memory and learning capabilities, a groundbreaking new study revealed — a huge advancement in Alzheimer's research

Menthol can improve worst symptoms of Alzheimer's, new study finds

BroBible

Remember Ameca, the world’s most advanced artificial intelligence-powered robot? Remember how she creepily shared with researchers her assurance that artificial intelligence and humanoid robots will never take over the world? “There’s no need to worry,” said Ameca. “We don’t believe you,” say researchers at Google Deepmind and the University of Oxford. “Under the conditions we […]
The post Oxford And Google Deepmind Researchers Claim AI Will ‘Likely’ Eliminate Humanity appeared first on BroBible.

Oxford And Google Deepmind Researchers Claim AI Will ‘Likely’ Eliminate Humanity

A recent study conducted by researchers at Kobe University Graduate School of Medicine, and published in the Journal of Psychiatric Research, reveals compelling evidence that alcohol dependence accelerates biological aging. By examining various epigenetic markers, the researchers found that individuals with alcohol dependence showed accelerated aging processes, which decelerated after a three-week treatment program.

Alcoholism is associated with accelerated biological aging

Scientists have found that people missing a specific blood group due to a genetic variant may be genetically predisposed to having obesity or overweight.

Missing a specific blood group may genetically predispose people to obesity

Summary: Researchers reversed Alzheimer’s symptoms in mice using a synthetic peptide, PHDP5, that targets brain function. The study shows that PHDP5 can cross the blood-brain barrier and restore memory by improving synaptic function. The treatment could delay cognitive decline if administered early. This breakthrough paves the way for new...

Synthetic Peptide Reverses Alzheimer’s Symptoms

Summary: Researchers developed a novel peptide, KS-133, to target cognitive dysfunction in schizophrenia. By using a brain-targeting peptide, KS-487, they successfully transported KS-133 across the blood-brain barrier. Their nanoparticle-based drug delivery system improved cognitive functions in mice, offering a new therapeutic strategy. Key Facts:. KS-133 targets the VIPR2 gene linked...

Peptide Improves Cognition in Schizophrenia

LiveScience

Excessive brain growth in the womb has been directly tied to autism in toddlers in new research involving lab-grown "minibrains."

Lab-grown 'minibrains' may have just confirmed a leading theory about autism

HealthDay

Certain gut bacteria play a key role in a person's risk for infection  Those that produce a beneficial fatty acid called butyrate help prevent infection, researchers report The findings pave the way for predicting one's personal risk FRIDAY, June 21, 2024 (HealthDay News) -- The bacteria colonizing your bowels play a key part in your risk for infection, new research shows.

Robust Gut Microbiome Can Help You Fight Infections

NewsBreak

Sulfur-based metabolites consumed by gut bacteria could be linked to neurodegenerative diseases

(CN) — Researchers with the American Society for Microbiology think that there may be a link between a chemical metabolized by the bacteria in the digestive...

Sulfur-based metabolites consumed by gut bacteria could be linked to neurodegenerative diseases

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