Article written by Emily Spencer, Edinburgh Napier University. Imagine a future where the smell of menthol could alleviate some of the worst symptoms of Alzheimer’s disease. This might sound like science fiction, but innovative new research is making it a potential reality. Scientists have discovered that when mice with...

Alzheimer’s patients could protect memory simply by inhaling menthol, mouse study shows

Summary: Researchers reversed Alzheimer’s symptoms in mice using a synthetic peptide, PHDP5, that targets brain function. The study shows that PHDP5 can cross the blood-brain barrier and restore memory by improving synaptic function. The treatment could delay cognitive decline if administered early. This breakthrough paves the way for new...

Synthetic Peptide Reverses Alzheimer’s Symptoms

Medical News Today

Researchers have successfully reversed the symptoms of Alzheimer’s disease in mice with a small, synthetic peptide called PHDP5.

Peptide treatment could reverse cognitive decline in Alzheimer's disease

Everyday Health

A new study links parental Alzheimer's to greater build-up of amyloid plaques in the brains of adult children, with maternal history posing greater risk than paternal history.

Your Dementia Risk May Increase if Your Mother Has Alzheimer's

Urolithin A is a natural compound shown to support memory and cognitive function and reduce brain inflammation. A new study in mice suggests that urolithin A may have therapeutic properties in treating Alzheimer’s disease. Consuming certain polyphenols, abundant in pomegranates, can increase gut bacteria’s production of urolithin A.

Could pomegranates help aid memory and ease Alzheimer’s symptoms?

The Independent

Scientists have revealed the results of a study looking at whether a person inherits risk of Alzheimer’s from their mother or father.The health history of your parents influence the danger of changes in the brain that lead to disease, according to the new study.It found that a family history of Alzheimer’s disease on the mother’s side might increase the chances of someone developing the condition.After evaluating 4,400 adults aged 65 to 85 who had memory loss and trouble solving problems, the researchers found those with a history of Alzheimer’s on either their mother’s side, or both parents’ sides, had increased...

Scientists reveal study on if you inherit Alzheimer’s from mother’s or father’s side

Irish Star

People with one key family member who were diagnosed with Alzheimer's at 65 or younger were also found to have higher-than-average amyloid levels in their brains, a new study has found

Alzheimer's risk is 'higher' if key member of your family has it

Community Voices represent independent, third-party users who have joined our contributor program but not yet verified their accounts. Community Voices are expected, like all users, to adhere to our Community Standards.

community_voice

Total Apex Sports & Entertainment

Do you know anyone who has dual nature? Such two-faced zodiac signs are friendly but they gossip about others behind their backs. They can lie to you without batting an eyelid. However, detecting a two-faced person isn’t easy for everyone. They often compliment their friends when they achieve a goal or change their wardrobe. But they will make negative remarks about you to someone else. What other traits do two-faced people have?

3 Zodiac Signs Who Are Two-Faced

Alzheimer's research may have found a way patients can protect their memory just by inhaling menthol, according to a new study. Alzheimer's disease is a neurodegenerative disease, meaning it worsens over time. Brain changes occur as neurons and connections die. Scientists at Edinburgh Napier University found that when mice with Alzheimer's inhaled menthol, their cognitive ability improved. The experiment, conducted over six months, involved repeatedly exposing mice with Alzheimer's to menthol. Researchers found that it lowered levels of interleukin-1 beta, a protein linked to cognitive decline in Alzheimer's. Menthol was also seen to mimic reducing T-regulatory cells, immune cells that control inflammation and balance the immune system. These new findings suggest a possible treatment for conditions like Alzheimer's.

Menthol May Be Key To Protecting Memory Loss From Alzheimer's

TheConversationAU

What’s the difference? is a new editorial product that explains the similarities and differences between commonly confused health and medical terms, and why they matter. Changes in thinking and memory as we age can occur for a variety of reasons. These changes are not always cause for concern. But when they begin to disrupt daily life, it could indicate the first signs of dementia.

What’s the difference between Alzheimer’s and dementia?

Summary: A new study shows GLP-1 receptor agonists increase pre-meal fullness by activating neurons in the dorsomedial hypothalamus. This mechanism helps prevent overeating, offering insights into obesity treatment. The research highlights how GLP-1 impacts food perception and hypothalamic responses to food cues, enhancing satiation before food intake. Key Facts:. GLP-1...

Ozempic Boost Fullness Pre-Meal via Hypothalamus

A new study reveals a link between gut microbiota and Parkinson's disease, finding that people may have fewer bacteria that produce riboflavin (vitamin B2) and biotin (vitamin B7).

Study suggests 2 vitamin B deficiencies may play a role in Parkinson's disease

San Diego, CA

Researchers at the University of California San Diego discovered that an unusually large brain could be the first sign of autism, potentially detectable in as early as the first trimester. Some children with autism face severe, enduring challenges including developmental delays, social difficulties, and possibly an inability to speak. Meanwhile,...

Scientists May Have Discovered the First Sign of Autism: An Unusually Large Brain

MRI illuminates the structural and functional organization of the brain -- thus helping clinicians predict the progression of Parkinson's disease in patients in its early stages, researchers have found. A team led by Silvia Basaia, PhD, of the IRCCS San Raffaele Scientific Institute in Milan, Italy, reported that Parkinson's "disease...

MRI predicts Parkinson's disease progression

New research has elucidated how an already identified area of the genome contributes to the development of a number of autoimmune or inflammatory diseases, including inflammatory bowel disease (IBD). The discovery of this genetic mechanism could help identify drugs that already exist that could be used to treat inflammatory bowel...

Scientists find new major cause of inflammatory bowel disease

Summary: Researchers discovered the serotonin 2C receptor in the brain plays a crucial role in regulating memory in both humans and animal models. This breakthrough offers insights into conditions associated with memory loss, such as Alzheimer’s disease, and suggests new treatment pathways. Mutations in the serotonin 2C receptor gene...

Serotonin 2C Receptor Key to Memory

In the dark and starry cosmic realm of astrology, some of the zodiac signs have an inflated sense of their intellect. Intelligence is a highly favored trait and these signs can often perceive themselves as the smartest people in the room. These signs can sometimes let their intellectual pride get the better of them. Tag along with us as we delve into the three zodiac signs renowned for their self-professed intelligence.

3 Zodiac Signs Who Think They're Smart

Review the multiple uses of metformin. A recent article on the multiple uses of metformin brings up the important topic of repurposing medications.1 Repurposing has been around since the advent of modern medicine. One prominent example is the use of chlorpromazine (CPZ) as an antipsychotic.2 Chlorpromazine was first synthesized in 1951 as a potentiator of general anesthesia.2 The psychiatric benefits were found later by Henri Laborit, a surgeon in the French army. He was doing research with artificial hibernation in prevention of surgical shock.2 Laborit employed the drug as an adjunct to anesthetics.2 He observed that CPZ at doses of 50 mg to 100 mg produced a lowering of body temperature, sedation, and disinterest without loss of consciousness.2 He was able to persuade his colleagues in the military hospital in Paris to try CPZ in the treatment of one of their patients who was experiencing psychotic agitation.2 Laborit hypothesized that since cooling with water had been used to treat agitation in France, the drug would have a similar effect.2 The mechanism of action was not fully known, and it was thought that it worked in controlling agitation because of its cooling effect and induction of “artificial hibernation” in patients.2 The pharmacological mechanism was not fully understood until many years later and the way it has impacted the practice of psychiatry needs no introduction. These “happy accidents” in medicine have played a vital role in getting where we are right now compared with just 50 years ago. This begs the question, are we onto another “happy accident” with metformin? There is an accumulating body of evidence that metformin may have benefits in aging that are beyond its effect on glycemic control.3.

Metformin, Inflammation, the Gut Microbiome, and Health Span: Connecting the Dots

Health

Medically reviewed by Smita Patel, DOMedically reviewed by Smita Patel, DOPOEMS syndrome is a very rare multisystem condition where the body's immune system attacks cells in the nervous system. This attack from the immune system is caused by an abnormal immune response to a cancerous tumor.POEMS syndrome symptoms include weakness of the arms and legs, darkening of the skin, and an abnormal increase in the size of lymph nodes and internal organs like the spleen or liver.POEMS syndrome is a chronic (long-term) disorder with no cure. In the United States, POEMS syndrome affects approximately 5,000 people. The disease occurs 1.5...

POEMS Syndrome

A Phase 2 clinical study of AB-1005 (AAV2-GDNF), an experimental gene therapy AskBio is developing for Parkinson’s disease, is recruiting patients who are experiencing motor fluctuations despite being on a stable medication regimen for at least a month. Called REGENERATE-PD (NCT06285643), the study aims to enroll 87 adults with...

Phase 2 AB-1005 gene therapy trial for Parkinson’s starts recruiting

NewsBreak

New Molecular Signatures Found for Alzheimer’s Disease

Summary: Researchers identified unique molecular signatures of blood-brain barrier dysfunction in Alzheimer’s disease. They discovered altered communication between brain vascular cells mediated by VEGFA and SMAD3...

New Molecular Signatures Found for Alzheimer’s Disease

Comments / 0