Columbus, OH

SurvivorNet

AstraZeneca leader wants more investment in technology to improve quality of care at community-based hospitals.

Head of Oncology at Pharma Giant AstraZeneca Leader Says Closing The Education & Care Gap For Community Patients And Doctors Is Crucial

Age at diagnosis, tumor size and immunosuppression were linked to reduced survival in resected adnexal carcinomas. Age was consistently associated with lower survival among other adnexal carcinoma groups. Factors such as age, tumor size and immunosuppression are linked with survival outcomes in localized adnexal carcinomas, according to a study. Cutaneous...

Age, tumor size, immunosuppression linked to poorer outcomes in adnexal carcinomas

More than half of the patients who received mitazalimab plus chemotherapy experienced an unconfirmed objective response in the phase 2 OPTIMIZE-1 study. Mitazalimab in combination with modified leucovorin calcium/folinic acid, fluorouracil, irinotecan, and oxaliplatin (mFOLFIRINOX) produced an overall survival (OS) benefit and elicited responses among patients with metastatic pancreatic cancer, according to a press release on 18-month follow-up data from the phase 2 OPTIMIZE-1 trial (NCT04888312).1.

Mitazalimab/Chemo Prolongs Survival, Responses in Pancreatic Cancer

Neil Segal, MD, discussed findings from a phase 1/2 trial investigating REGN7075 in patients with solid tumors refractory to immunotherapy. June is Cancer Immunotherapy Month, and Targeted Oncology is highlighting stories on this developing field of research. REGN7075, a new type of immunotherapy drug, is being investigated for its ability...

Immunotherapy for Cold Tumors: REGN7075 Effective in Early Trials

Author(s): Suresh S. Ramalingam, MD, FACP, FASCO Chandler Park, MD, MSc, FACP. Suresh S. Ramalingam, MD, FACP, FASCO, and Chandler H. Park, MD, FACP, discuss updates in non–small cell lung cancer at the 2024 ASCO Annual Meeting. Now Viewing. Suresh S. Ramalingam, MD, FACP, FASCO, professor, Department of Hematology...

Dr Ramalingam on Updates in Lung Cancer Following the 2024 ASCO Annual Meeting

Metformin, a medication commonly used to treat type 2 diabetes, helps the body regulate sugar in the bloodstream. Part of the class of drugs known as biguanides, metformin reduces the amount of sugar you absorb from food and the amount produced by the liver. Metformin also impacts the way the body will respond to insulin, the natural substance that regulates blood sugar levels.

Diabetes Drug Metformin Investigated for Cancer Prevention Use

Factors such as age, sex, and family history can impact a person’s risk of getting pancreatic cancer. It is more likely to occur later in life. Certain conditions can also increase the likelihood of pancreatic cancer. Pancreatic cancer develops in the tissues of the pancreas. This organ secretes digestive...

Who is most likely to get pancreatic cancer?

Ohtuvayre is the first inhaled product with a novel mechanism of action for chronic obstructive pulmonary disease to be approved in 20 years. The FDA has approved Verona Pharma’s Ohtuvayre (ensifentrine) for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adult patients. Classified as a first-in-class selective dual inhibitor of phosphodiesterase 3 and 4 (PDE3 and PDE4), the treatment combines bronchodilator and non-steroidal anti-inflammatory effects in one molecule. According to the company, this marks the first time in 20 years that an inhaled product with a novel mechanism of action has been approved for COPD maintenance.1.

FDA Approves Verona’s Ohtuvayre for the Maintenance Treatment of Chronic Obstructive Pulmonary Disease

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Total Apex Sports & Entertainment

Have you ever met someone who is wise beyond their age? Such people are often referred to as old souls. They understand life and the world better than many zodiac signs. A soul’s age doesn’t necessarily match a person’s actual age. Instead, it advances based on the life experiences someone has.

3 Zodiac Signs Who Are Old Souls

Anika Jindal

A subtle sign of low intelligence is an inability to understand or appreciate complexity. People with low intelligence may have difficulty understanding abstract concepts or thinking outside the box. They may also be more likely to believe simplistic explanations or conspiracy theories.

12 Subtle Signs Of Low Intelligence

Physician scientists from City of Hope, one of the largest cancer research and treatment organizations in the United States, found that people with metastatic kidney cancer who orally took a live biotherapeutic product called CBM588 while in treatment with immunotherapy and enzymatic tyrosine kinase inhibitors experienced improved health outcomes. The phase 1 trial was published today in Nature Medicine.

Changing the gut microbiome improves health outcomes for people new metastatic kidney cancer

Newark, NJ

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Morristown Minute

NEWARK, N.J. – Eight individuals associated with the "793 Bloods" street gang, a subset of the national Bloods gang, have been charged for their roles in a Newark-based drug trafficking organization, U.S. Attorney Philip R. Sellinger announced.

Eight '793 Bloods' Gang Members Charged in Newark Drug Network

California State

Alameda Post

California regulators just stopped AT&T from pulling the plug. California’s Public Utilities Commission on June 20 rejected AT&T’s application to stop providing landlines and other services in areas where there is no other option.

Still Need Your Landline?

The following is a summary of “Pilot Intervention to increase uptake of lung cancer screening through the emergency department,” published in the May 2024 issue of Emergency Medicine by Pettit, et al. For a study, researchers sought to explore the viability of referring patients for lung cancer screening...

Pilot Program to Boost Lung Cancer Screening Uptake via the Emergency Department

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Chicago Happenings

What is more summery than an icy, sweet frozen drink? If the heat wave is getting to you, try whipping up this simple frozen strawberry lemonade. All you need is your choice of lemonade and some frozen strawberries. You can use store-bought lemonade, make your own from scratch, or a powdered version. As for strawberries, frozen ones are the easiest choice. If you'd rather use fresh, add at least two cups of ice until you reach a nice, frozen consistency.

2-Ingredient Frozen Strawberry Lemonade: Beat the Heat!

Black Coffee and Blue Jeans

Thyroid cancer is a type of cancer that originates in the thyroid gland, a butterfly-shaped gland located at the base of the neck, just below the Adam's apple. The thyroid gland produces hormones that regulate heart rate, blood pressure, body temperature, and your weight. There are several types of thyroid cancer, to include: Papillary Thyroid Cancer, (the most common type), Follicular Thyroid Cancer, hurthle cell cancer, Medullary Thyroid Cancer, , and Anaplastic Thyroid Cancer, the rarest type but most aggressive, and thyroid lymphoma.

Thyroid Cancer: Risks, Symptoms & Treatments

Colorectal cancer (CRC) is a term for cancers that begin in the colon or rectum. Determining the stage of colorectal cancer is important because it helps determine treatment options and, ultimately, the prognosis of the disease. This article will review the stages of colorectal cancer, how each stage is determined,...

Colorectal Cancer Stages and Treatment Effectiveness

New York City, NY

The e-Texan

New York – As Trump anticipates his sentencing on July 11th in the New York hush money case, Florida Judge Aileen Cannon made a ruling this Monday. Despite rejecting Trump’s legal team's request to dismiss several charges in the classified documents case, she conceded on a minor point. She removed a portion of the charges that referenced an uncharged allegation, but upheld the other charges.

Legal expert says Trump should not be jailed after New York guilty verdict because he is ‘too old’

Various improvements were seen in 2 adult patients and 2 pediatric patients treated in separate clinical trials. Taysha Gene Therapies’ TSHA-102, an investigational adeno-associated virus (AAV) vector-based gene therapy, has continued to generate positive efficacy and safety data in updated results from the phase 1/2 REVEAL adolescent and adult clinical trial (NCT05606614) and the separate phase 1/2 REVEAL Pediatric Study clinical trial (NCT06152237).1.

Taysha’s Rett Syndrome Gene Therapy TSHA-102 Continues to Show Promise in Adult and Pediatric Patients

Missouri State

CJ Coombs

The first time my family walked into a Ponderosa Steakhouse was in the late 1960s. It was new and the experience was great. Like other new restaurants, if the management doesn't stay on top, the quality of service can decline. The location we went to did change through the years, but in the beginning, it was great.

The 1960s: the Ponderosa and Bonanza Steakhouses are still around in some states

NewsBreak

The Targeted Pulse: An Approval for Colorectal Cancer, AI Model Enhances Palliative Care, and More

The FDA approved adagrasib with cetuximab for KRAS G12C-mutated CRC and an AI-driven mortality models improve palliative care. We also cover data on datopotamab deruxtecan showing...

The Targeted Pulse: An Approval for Colorectal Cancer, AI Model Enhances Palliative Care, and More

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