Columbus, OH

ScienceAlert


Researchers have discovered how a cell surface protein called Aplp1 can play a role in spreading material responsible for  Parkinson's disease from cell-to-cell in the brain.
Promisingly, an FDA-approved  cancer drug that targets another protein called Lag3 – which interacts with Aplp1 – blocks the spread in mice, suggesting a potential therapy may already exist.



					
			

In a new paper, an international team of scientists describes how the two proteins work together to help harmful alpha-synuclein protein clumps get into brain cells.
"Now that we know how Aplp1 and Lag3 interact, we have a new way of understanding how alpha-synuclein contributes to...

Parkinson's Discovery Suggests We May Already Have an FDA-Approved Treatment

Medical News Today

Researchers have successfully reversed the symptoms of Alzheimer’s disease in mice with a small, synthetic peptide called PHDP5.

Peptide treatment could reverse cognitive decline in Alzheimer's disease

A recent study has unveiled new insights into the neural mechanisms underlying treatment-resistant depression. By recording stereotactic electroencephalography signals (sEEG) from patients’ brains, the team identified specific abnormalities in how depressed individual process emotional information. This study, published in Nature Mental Health, provides a promising step towards understanding and potentially treating this challenging condition.

Researchers identify brain abnormalities in treatment-resistant depression

San Diego, CA

Researchers at the University of California San Diego discovered that an unusually large brain could be the first sign of autism, potentially detectable in as early as the first trimester. Some children with autism face severe, enduring challenges including developmental delays, social difficulties, and possibly an inability to speak. Meanwhile,...

Scientists May Have Discovered the First Sign of Autism: An Unusually Large Brain

Writers represent independent, third-party users who have joined our contributor program and self-verified their accounts. Writers are expected, like all users, to adhere to our Community Standards.

writer

Fareeha Arshad

Researchers at Washington State University have uncovered the neurological basis behind the infamous cannabis-induced "munchies" phenomenon. Their study, conducted on mice, is the first to investigate how cannabis affects the real-time activity of brain regions responsible for appetite control.

Scientists Discover How Cannabis Triggers Munchies in the Brain

Autism is popularly perceived as a genetic condition that impacts the functioning of various brain mechanisms. The amygdala theory of autism states that autistic individuals differ in the functioning of their amygdala. Researchers suggest more complex differences in a network of structures connected with the amygdala. The amygdala is a...

Autism and the Brain

Some time deep in our evolutionary past, most likely more than once, a significant amount of Neanderthal DNA became mixed in with our own, influencing everything from how we now fight illness to even our appearance. A new study by researchers from Clemson University and Loyola University in the US...

Autism Linked With DNA Our Ancestors Inherited From Neanderthals

Hey everyone! I’m here today to shine a light on a critical issue that often goes unnoticed- the health challenges faced by the autistic community. A recent study by University College London, published in The Lancet Regional Health—Europe, has revealed something startling in the hidden health struggles of autism.

The Hidden Health Struggles of Autism

Summary: Researchers reversed Alzheimer’s symptoms in mice using a synthetic peptide, PHDP5, that targets brain function. The study shows that PHDP5 can cross the blood-brain barrier and restore memory by improving synaptic function. The treatment could delay cognitive decline if administered early. This breakthrough paves the way for new...

Synthetic Peptide Reverses Alzheimer’s Symptoms

The ovaries are involved in far more than just reproduction. The two oval-shaped glands that float on either side of the uterus don't just produce and release eggs, they also pump out hormones that help keep a person's heart, bones, brain, and immune system healthy as they age. A new...

Losing Both Ovaries Could Come at a Serious Cost to The Brain, Researchers Find

Research teams have successfully regenerated mouse brain circuits using rat stem cells, showcasing a new method for restoring brain function and studying interspecies brain development. These findings open up possibilities for treating neurological diseases and understanding brain evolution, while also hinting at future clinical applications and ethical challenges in using...

Revolutionizing Regeneration: Rat Stem Cells Restore Mouse Brain Circuits

If at least two of your close family members have had a brain aneurysm, genetic testing may help identify if you’re at risk. A brain aneurysm is a bulge in one of your brain’s blood vessels. The flow of blood may lead to pressure on a thin, weakened vessel wall, causing an aneurysm to form and become larger.

Genetic Testing for Hereditary Brain Aneurysms

LiveScience

Excessive brain growth in the womb has been directly tied to autism in toddlers in new research involving lab-grown "minibrains."

Lab-grown 'minibrains' may have just confirmed a leading theory about autism

A brain tumor can feel like many other medical conditions and may cause a variety of symptoms. Brain tumors can be cancerous or non-cancerous and may not initially cause symptoms. The most common symptoms of a brain tumor include headaches, dizziness, seizures, or vision changes. The effects can vary based...

What Does a Brain Tumor Feel Like?

Some environmental factors that occur during or before birth may increase the chance of autism. Examples include parental physical and mental health, certain medications during pregnancy, or fetal complications resulting in an extended lack of oxygen. Autism is a neurodevelopmental condition that affects how people interact, behave, and communicate. Environmental...

What role does the environment play in autism?

Virginia State

Cheryl E Preston

Etiquette and Miss Emily Post once frowned upon females who sat gap-legged in public. In Virginia, books in school libraries, teen magazines, and older females often suggested that young ladies cross their legs at the ankle while seated.

"Cross your legs at the ankle young lady" is not totally forgotten today

There is no cure for autism, and autistic people do not require curative treatment. Instead, there are options available to support autistic people, which may involve psychological, behavioral, and educational therapy. People sometimes refer to autism as autism spectrum disorder (ASD). The level of support autistic people require can vary...

Treatment and support for autistic individuals

(CN) — Researchers with the American Society for Microbiology think that there may be a link between a chemical metabolized by the bacteria in the digestive system, known as DHPS, and three neurodegenerative diseases. Presented at ASM Microbe, the society's annual meeting, on Sunday, the research is one of...

Sulfur-based metabolites consumed by gut bacteria could be linked to neurodegenerative diseases

The beach has long been a favorite destination for relaxation and recreation. But beyond the obvious appeal of sun, sand, and surf, there’s a hidden benefit to spending time by the shore: it’s good for your brain. Recent research suggests that the beach environment offers unique brain health and function advantages. Let’s explore how the coastal experience can boost your cognitive wellness.

How The Beach Benefits Your Brain

Distractify

On Thursday, June 27, 2024, actor and comedian Martin Mull died after a long battle with an illness he hadn't been very forthcoming about with the general public. His daughter, Maggie Mull, shared on Instagram that Martin died "after a valiant fight against a long illness," but what was Martin Mull's cause of death exactly?He was 80 years old at the time of his death. To some, he was known as Roseanne's sarcastic boss in the original Roseanne series. He also played a long-running recurring character in Sabrina, the Teenage Witch. To others, Martin is remembered as a comedic actor...

Martin Mull's Daughter Says the Actor Died After a "Vigilant Fight Against a Long Illness"

NewsBreak

Brain Protein Discovery Could Lead to New Autism Treatments

A crucial protein in early brain development could hold the key to preventing autism and other neurological disorders. Researchers at Cold Spring Harbor Laboratory have identified...

Brain Protein Discovery Could Lead to New Autism Treatments

Comments / 0