Donanemab-azbt is the first and only amyloid plaque-targeting therapy approved for adults with early symptomatic Alzheimer disease. The FDA granted approval for donanemab-azbt for the treatment of adults with early symptomatic Alzheimer disease.1. The novel agent, which will be marketed as Kisunla, was developed by Eli Lilly and Company and...

FDA Approves Donanemab for Early Alzheimer Disease

ScienceAlert


Researchers have discovered how a cell surface protein called Aplp1 can play a role in spreading material responsible for  Parkinson's disease from cell-to-cell in the brain.
Promisingly, an FDA-approved  cancer drug that targets another protein called Lag3 – which interacts with Aplp1 – blocks the spread in mice, suggesting a potential therapy may already exist.



					
			

In a new paper, an international team of scientists describes how the two proteins work together to help harmful alpha-synuclein protein clumps get into brain cells.
"Now that we know how Aplp1 and Lag3 interact, we have a new way of understanding how alpha-synuclein contributes to...

Parkinson's Discovery Suggests We May Already Have an FDA-Approved Treatment

Medical News Today

Researchers have successfully reversed the symptoms of Alzheimer’s disease in mice with a small, synthetic peptide called PHDP5.

Peptide treatment could reverse cognitive decline in Alzheimer's disease

Scripps News

The drug from Eli Lilly is an amyloid-plaque targeting therapy — a protein that is associated with the disease's development.

FDA approves Alzheimer's drug shown to slow decline in memory, cognition in those with the disease

Article written by Emily Spencer, Edinburgh Napier University. Imagine a future where the smell of menthol could alleviate some of the worst symptoms of Alzheimer’s disease. This might sound like science fiction, but innovative new research is making it a potential reality. Scientists have discovered that when mice with...

Alzheimer’s patients could protect memory simply by inhaling menthol, mouse study shows

Memory loss and confusion get all the attention as common dementia symptoms. But missing its more subtle signs can delay help. With 6.7 million seniors affected, dementia is widespread yet often undiagnosed. What red flags should we watch for in ourselves and loved ones? When should we seek screening? Here’s what to know:

The Biggest Early Warning Sign of Dementia That Most People Miss

GeekSpin

The menu board at McDonald’s is about to get a makeover because some of your most cherished menu items are about to bid adieu. Read on to discover which McDonald’s items are departing and why you’ll want to make a flavor pilgrimage to savor them one last time before they’re gone for good. McDonald’s Salads […]
McDonald’s Announces Farewell to These Beloved Menu Items

McDonald’s Announces Farewell to These Beloved Menu Items

Neurosurgeon and CNN chief medical correspondent Dr. Sanjay Gupta discusses a study that may show greater insight into preventing Alzheimer’s, and he asks for the public’s questions about the disease. 

How much of Alzheimer’s disease is preventable? Dr. Gupta weighs in

The early signs of dementia in women include memory loss and confusion. Dementia is a collective term that describes various symptoms of cognitive decline, such as forgetfulness, confusion, and changes in behavior. It is not a specific disease but a group of conditions characterized by impairment of at least two brain functions, such as memory loss and judgment.

Early signs of dementia in women

Intelligence is a complex and multifaceted concept that has captivated the minds of researchers, psychologists, and everyday people for centuries. While there is no single, universally accepted definition of intelligence, it is generally understood to encompass a wide range of cognitive abilities, such as problem-solving, learning, and adaptation. In recent years, scientists have sought to uncover the critical indicators of genuine intelligence, drawing from a wealth of psychological research and empirical evidence. This article explores nine science-backed signs that suggest an individual possesses a high level of intelligence.

9 Signs You’re Genuinely Smart, According to Psychology

The Independent

Scientists have revealed the results of a study looking at whether a person inherits risk of Alzheimer’s from their mother or father.The health history of your parents influence the danger of changes in the brain that lead to disease, according to the new study.It found that a family history of Alzheimer’s disease on the mother’s side might increase the chances of someone developing the condition.After evaluating 4,400 adults aged 65 to 85 who had memory loss and trouble solving problems, the researchers found those with a history of Alzheimer’s on either their mother’s side, or both parents’ sides, had increased...

Scientists reveal study on if you inherit Alzheimer’s from mother’s or father’s side

TheConversationAU

What’s the difference? is a new editorial product that explains the similarities and differences between commonly confused health and medical terms, and why they matter. Changes in thinking and memory as we age can occur for a variety of reasons. These changes are not always cause for concern. But when they begin to disrupt daily life, it could indicate the first signs of dementia.

What’s the difference between Alzheimer’s and dementia?


Researchers connecting pieces of the massive  Alzheimer's puzzle are closer to slotting the next one in place, with yet another link between our guts and brain.
Animal studies have demonstrated Alzheimer's can be passed on to young mice through a transfer of gut microbes, confirming a link between the digestive system and the health of the brain.



					
			

A 2023 study adds further support to the theory that inflammation could be the mechanism through which this occurs.
"We showed people with Alzheimer's disease have more gut inflammation," University of Wisconsin psychologist Barbara Bendlin said when the research was published, "and among people with...

Gut Inflammation Linked to Alzheimer's Disease, Once Again

The Guardian

Maureen Callahan’s eye-opening exposé looks back at the Kennedy men and the women they ‘destroyed’, digging into a long and grisly history

‘They always got away with it’: new book reveals Kennedys’ shocking treatment of women

Newark, NJ

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Morristown Minute

NEWARK, N.J. – Eight individuals associated with the "793 Bloods" street gang, a subset of the national Bloods gang, have been charged for their roles in a Newark-based drug trafficking organization, U.S. Attorney Philip R. Sellinger announced.

Eight '793 Bloods' Gang Members Charged in Newark Drug Network

Irish Star

People with one key family member who were diagnosed with Alzheimer's at 65 or younger were also found to have higher-than-average amyloid levels in their brains, a new study has found

Alzheimer's risk is 'higher' if key member of your family has it

Summary: The Alzheimer’s Association released revised diagnostic and staging criteria for Alzheimer’s disease, incorporating the latest research and biomarkers to better define and manage the condition. Takeaways:. Biomarker Integration: The new criteria include updated biomarker classifications that leverage both traditional and blood-based markers, enabling earlier and more precise...

Alzheimer’s Association Revises Criteria for Diagnosis and Staging of Alzheimer’s

The Mirror US

Today, the US FDA greenlit a new drug for distribution, one that can help patients avoid the extremes of Alzheimer's by treating it early with the medication Kisunla, which scrapes 'plaque' from the brain

FDA approves 'miracle' drug that can slow Alzheimer's by 'scraping brain plaque'

Early memory complaints, validated by partners, are linked to increased tau tangles in the brain, emphasizing the potential of early Alzheimer’s detection and intervention. Individuals who report early memory problems and whose partners also suspect they have memory problems have higher levels of tau tangles in the brain, a biomarker associated with Alzheimer’s disease. This is according to a study published in the May 29, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

These Signs of Memory Loss Could Actually Predict Alzheimer’s Brain Changes

New York Post

In 1982, retiree Donald Dorff was the first person to be diagnosed with a sleep disorder that, unbeknownst to him at the time, would unlock monumental breakthroughs in research for dementia and Parkinson’s.

The disorder in question, “rapid eye movement sleep behavior disorder” or RBD, caused Dorff to engage in violent movement while asleep. He was able to inflict harm on himself during REM sleep, a period when the body is supposed to be paralyzed while dreaming.

“Limb jerking, twitching, throwing out your arm, throwing punches, kicking, sitting up, standing, jumping out of bed and running. Those behaviors are very typical with...

I told a doctor about my weird sleep disorder — it’s leading to major breakthroughs in Parkinson’s and dementia research

NewsBreak

Voices of Alzheimer's Applauds Approval of Kisunla for Early Alzheimer's Disease Treatment

(Precision Vaccinations News) — Voices of Alzheimer's, a national advocacy organization led by people living with Alzheimer's disease, today announced it celebrates the U.S. Food and...

Voices of Alzheimer's Applauds Approval of Kisunla for Early Alzheimer's Disease Treatment

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