The Mirror US

Today, the US FDA greenlit a new drug for distribution, one that can help patients avoid the extremes of Alzheimer's by treating it early with the medication Kisunla, which scrapes 'plaque' from the brain

FDA approves 'miracle' drug that can slow Alzheimer's by 'scraping brain plaque'

Donanemab-azbt is the first and only amyloid plaque-targeting therapy approved for adults with early symptomatic Alzheimer disease. The FDA granted approval for donanemab-azbt for the treatment of adults with early symptomatic Alzheimer disease.1. The novel agent, which will be marketed as Kisunla, was developed by Eli Lilly and Company and...

FDA Approves Donanemab for Early Alzheimer Disease

Some signs of Alzheimer’s disease include repeatedly asking questions, misplacing items, forgetting names and more. Recent research suggests financial symptoms also can appear leading up to a diagnosis. Researchers with Georgetown University in Washington, D.C., and the Federal Reserve Bank of New York recently found a link between financial...

2 Money Woes That Could Signal Alzheimer’s Years in Advance

Medical News Today

Researchers have successfully reversed the symptoms of Alzheimer’s disease in mice with a small, synthetic peptide called PHDP5.

Peptide treatment could reverse cognitive decline in Alzheimer's disease

ScienceAlert


Researchers have discovered how a cell surface protein called Aplp1 can play a role in spreading material responsible for  Parkinson's disease from cell-to-cell in the brain.
Promisingly, an FDA-approved  cancer drug that targets another protein called Lag3 – which interacts with Aplp1 – blocks the spread in mice, suggesting a potential therapy may already exist.



					
			

In a new paper, an international team of scientists describes how the two proteins work together to help harmful alpha-synuclein protein clumps get into brain cells.
"Now that we know how Aplp1 and Lag3 interact, we have a new way of understanding how alpha-synuclein contributes to...

Parkinson's Discovery Suggests We May Already Have an FDA-Approved Treatment

The early signs of dementia in women include memory loss and confusion. Dementia is a collective term that describes various symptoms of cognitive decline, such as forgetfulness, confusion, and changes in behavior. It is not a specific disease but a group of conditions characterized by impairment of at least two brain functions, such as memory loss and judgment.

Early signs of dementia in women

TheConversationAU

What’s the difference? is a new editorial product that explains the similarities and differences between commonly confused health and medical terms, and why they matter. Changes in thinking and memory as we age can occur for a variety of reasons. These changes are not always cause for concern. But when they begin to disrupt daily life, it could indicate the first signs of dementia.

What’s the difference between Alzheimer’s and dementia?

The Independent

Scientists have revealed the results of a study looking at whether a person inherits risk of Alzheimer’s from their mother or father.The health history of your parents influence the danger of changes in the brain that lead to disease, according to the new study.It found that a family history of Alzheimer’s disease on the mother’s side might increase the chances of someone developing the condition.After evaluating 4,400 adults aged 65 to 85 who had memory loss and trouble solving problems, the researchers found those with a history of Alzheimer’s on either their mother’s side, or both parents’ sides, had increased...

Scientists reveal study on if you inherit Alzheimer’s from mother’s or father’s side

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Total Apex Sports & Entertainment

People have different levels of maturity. An individual’s age or upbringing can make them possess certain traits. Yet, most people believe that one matures as they grow old. On the contrary, some zodiac signs appear childish in old age. They are jumpy and careless. This strains their relationships with signs who misunderstand them. Air and fire signs are temperamental and some people refer to them as being childish. How can you identify an immature sign?

3 Zodiac Signs Who Are Immature

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NewSantaAna

The FBI has seen a rise in scams targeting timeshare owners. In this kind of scam, criminals con these part-time property owners into shelling out hefty sums of cash, all under false pretenses related to their timeshare properties.

FBI warns that Mexican cartels are targeting Americans with timeshare scams

Summary: The Alzheimer’s Association released revised diagnostic and staging criteria for Alzheimer’s disease, incorporating the latest research and biomarkers to better define and manage the condition. Takeaways:. Biomarker Integration: The new criteria include updated biomarker classifications that leverage both traditional and blood-based markers, enabling earlier and more precise...

Alzheimer’s Association Revises Criteria for Diagnosis and Staging of Alzheimer’s

Newark, NJ

Morristown Minute

NEWARK, N.J. – Eight individuals associated with the "793 Bloods" street gang, a subset of the national Bloods gang, have been charged for their roles in a Newark-based drug trafficking organization, U.S. Attorney Philip R. Sellinger announced.

Eight '793 Bloods' Gang Members Charged in Newark Drug Network

TheDailyBeast

The Federal Drug Administration gave the go-ahead to a second Alzheimer’s treatment Tuesday after a study suggested that it could slow the symptoms of the disease.The drug, developed by Eli Lilly, is called donanemab and will be sold under the name “Kisunla” when it hits the market. The pharmaceutical giant has not set a release date.Eli Lilly, which makes the anti-obesity drug Mounjaro, saw its shares rise slightly on the FDA approval.The drug is for people at the early stages of Alzheimer’s and is administered by an infusion of a monoclonal antibody once every four weeks. Its cost will start...

FDA Approves Second Alzheimer’s Drug after Trial Shows it Can Slow Disease by 35%

Eli Lilly said it applied for U.S. approval of its weight loss drug Zepbound for the treatment of the most common sleep-related breathing disorder and expects regulators to make a decision as early as the end of the year. The company released additional data from two late-stage trials showing that...

Eli Lilly expects FDA decision on weight loss drug Zepbound for sleep apnea as early as end of the year

Scripps News

The drug from Eli Lilly is an amyloid-plaque targeting therapy — a protein that is associated with the disease's development.

FDA approves Alzheimer's drug shown to slow decline in memory, cognition in those with the disease

Ali Carney, 46, of Newark, received a 65-month prison sentence for conspiring to distribute narcotics, including fentanyl and heroin, and possessing with intent to distribute fentanyl, according to U.S. Attorney Philip R. Sellinger.

Gang Member Sentenced to 65 Months for Drug Trafficking

Fox News

The FDA has approved a new medication for people with Alzheimer’s disease. Eli Lilly’s Kisunla (donanemab) is a once-monthly injection intended for adults with early symptomatic Alzheimer's disease.

FDA approves new drug for Alzheimer’s disease: ‘Meaningful results’

The Hill

The Food and Drug Administration (FDA) on Tuesday approved Eli Lilly’s Alzheimer’s drug, the company announced, clearing the way for another entry into the market of a new class of drugs that moderately slows the disease’s progression.  The agency last month held an advisory panel meeting to scrutinize the safety and effectiveness of the drug,…

FDA approves Lilly’s new Alzheimer’s drug after delay

This announcement follows an earlier FDA decision to grant approval to the company’s tissue-based comprehensive genomic profiling test FoundationOne CDx for the same therapy and indication in August 2023. The FDA has approved the liquid biopsy test FoundationOneLiquid CDx for use as a companion diagnostic in identifying patients with...

FDA approves FoundationOneLiquid CDx for niraparib/abiraterone in mCRPC

Throughout June, the FDA approved drugs for the treatment of diseases including myelodysplastic syndrome, thyroid cancer, endometrial cancer, colorectal cancer, and follicular lymphoma. Throughout the month of June, several cancer therapies have received FDA approval for diseases including thyroid cancer, myelodysplastic syndrome (MDS), colorectal cancer (CRC), endometrial cancer, and follicular...

Oncology Drugs Approved by the FDA in June 2024

NewsBreak

Second Alzheimer’s drug approved by FDA

The FDA has approved a new Alzheimer’s drug called Kisunla from Eli Lilly, which can modestly slow the progression of the disease in patients with mild...

Second Alzheimer’s drug approved by FDA

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