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Researchers have identified a series of blood markers that betray the presence of Parkinson's disease up to seven years before most symptoms present. If findings from this small study can be replicated in larger populations, a simple blood test could be developed to identify those at risk.
With around 10 million people impacted by Parkinson's globally, there is an urgent need to develop better treatments and preventative strategies. One of the reasons this has proved challenging is our inability to identify people at risk of Parkinson's early enough to trial mitigation strategies.

So, University College London biochemist Jenny Hällqvist and colleagues used...

New Test Detects Parkinson's 7 Years Before Most Symptoms Show

Researchers found that inhibiting the degradation of vitamin B6 in cells using 7,8-Dihydroxyflavone enhances brain functions and could offer a new treatment method for mental and neurodegenerative disorders. Vitamin B6 plays a crucial role in brain metabolism. Consequently, low levels of vitamin B6 are linked to memory and learning impairments,...

Scientists Uncover Brain-Boosting Potential of Vitamin B6

Parkinson’s disease is a chronic brain disorder that leads to abnormal brain functions and can affect the nervous system. As a result, patients with Parkinson’s have issues with pain, movement, sleep, and mental health. Common symptoms include tremors, painful muscle contractions, stiffness, loss of balance, slow movement, reduced coordination, difficulty speaking, and others. Unfortunately, there is no cure for Parkinson’s and symptoms worsen over time. However, there are therapies that regulate symptoms to slow disease progression and improve quality of life.

Cancer Immunotherapy Applied to Parkinson's Disease

(CN) — Researchers with the American Society for Microbiology think that there may be a link between a chemical metabolized by the bacteria in the digestive system, known as DHPS, and three neurodegenerative diseases. Presented at ASM Microbe, the society's annual meeting, on Sunday, the research is one of...

Sulfur-based metabolites consumed by gut bacteria could be linked to neurodegenerative diseases

Once-daily treatment with Gain Therapeutics‘ GT-02287 rescued motor function and cognitive performance in a mouse model of Parkinson’s disease associated with mutations in the GBA1 gene. “These data further confirm our conviction that GT-02287 can slow or stop progression of Parkinson’s disease and given the cognitive decline observed...

GT-02287 rescues motor, cognitive function in Parkinson’s mice

Vitamin B12 deficiency is common. It can lead to various health issues, affecting everything from energy levels to brain function. Vitamin B12, or cobalamin, is an essential nutrient in meat, fish, and dairy products. It is crucial for red blood cell production and a healthy nervous system. When B12 levels...

Unusual symptoms of B12 deficiency

A recent preclinical study found that supplementation with a branded pomegranate extract called Pomanox, from Euromed, may support liver health and alleviate fructose-induced metabolic impairment. A recent preclinical study1 found that supplementation with a branded pomegranate extract (Pomanox from Euromed based in Mollet del Vallès, Spain) may support liver health...

Animal study finds that branded pomegranate extract may alleviate the impacts of fructose consumption on liver metabolism

Some weird signs of iron deficiency include developing a craving for ice or clay, an overwhelming urge to move the legs, and hair loss. However, iron deficiency can cause a range of symptoms. Iron deficiency describes when a person does not have enough iron in their body. When iron levels...

5 weird signs of iron deficiency

A major cause of inflammatory bowel disease (IBD) has been discovered by UK scientists. They found a weak spot in our DNA that is present in 95% of people with the disease. It makes it much easier for some immune cells to go haywire and drive excessive inflammation in the bowels.

Major cause of inflammatory bowel disease found

Last Segment of the World’s Largest Telescope Mirror Successfully Cast. Set for completion this decade, the Extremely Large Telescope in Chile will be the largest telescope globally, with a main mirror spanning 39 meters and made from 798 precision-engineered segments. It represents a significant international effort in astronomy. Currently...

Extremely Large Telescope: World’s Largest Telescope Mirror Will Bring the Stars Closer to Earth

Review the multiple uses of metformin. A recent article on the multiple uses of metformin brings up the important topic of repurposing medications.1 Repurposing has been around since the advent of modern medicine. One prominent example is the use of chlorpromazine (CPZ) as an antipsychotic.2 Chlorpromazine was first synthesized in 1951 as a potentiator of general anesthesia.2 The psychiatric benefits were found later by Henri Laborit, a surgeon in the French army. He was doing research with artificial hibernation in prevention of surgical shock.2 Laborit employed the drug as an adjunct to anesthetics.2 He observed that CPZ at doses of 50 mg to 100 mg produced a lowering of body temperature, sedation, and disinterest without loss of consciousness.2 He was able to persuade his colleagues in the military hospital in Paris to try CPZ in the treatment of one of their patients who was experiencing psychotic agitation.2 Laborit hypothesized that since cooling with water had been used to treat agitation in France, the drug would have a similar effect.2 The mechanism of action was not fully known, and it was thought that it worked in controlling agitation because of its cooling effect and induction of “artificial hibernation” in patients.2 The pharmacological mechanism was not fully understood until many years later and the way it has impacted the practice of psychiatry needs no introduction. These “happy accidents” in medicine have played a vital role in getting where we are right now compared with just 50 years ago. This begs the question, are we onto another “happy accident” with metformin? There is an accumulating body of evidence that metformin may have benefits in aging that are beyond its effect on glycemic control.3.

Metformin, Inflammation, the Gut Microbiome, and Health Span: Connecting the Dots

Scientists developed a new model that could help inform guidelines and improve evidence-based advice on the risks and benefits of fish consumption, especially during pregnancy. In a paper published on June 28 in The American Journal of Epidemiology, researchers from Brigham and Women’s Hospital, a founding member of Mass General Brigham; Harvard T.H. Chan School of Public Health; University of Rochester Medical Center; and Cornell University present a new framework that takes into account estimated average mercury content in consumed fish, helping weigh the detrimental effects of mercury against the potential benefits of nutrients found in fish.

The Truth About Fish and Pregnancy: What’s Safe and What’s Not

rolling out

Pancreatic cancer is a daunting diagnosis that affects thousands of people worldwide every year. One of the most challenging aspects of this disease is its subtlety; the symptoms often mimic those of other, less severe conditions. This similarity can lead to delayed diagnosis and treatment, significantly impacting the prognosis. Understanding why pancreatic cancer symptoms resemble other diseases’ symptoms is crucial for early detection and better outcomes. This article will delve into the reasons behind this symptom overlap, explore common symptoms of pancreatic cancer, and provide insights on differentiating these symptoms from other ailments.

Why pancreatic cancer symptoms are similar to other diseases

New research has revealed that regular walking significantly extended pain-free periods for adults with low back pain, proving its effectiveness and affordability as a preventive measure. A groundbreaking study has found that adults with a history of low back pain experienced nearly twice the duration without a recurrence when they...

Scientists Discover Surprisingly Simple Method To Ease Lower Back Pain

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Total Apex Sports & Entertainment

There are certain zodiac signs that most people are careful with because of their fiery and low tolerance levels. You can hardly mess with individuals with such signs without getting a backlash. Whether they are in work environments or family settings, they do not hesitate to set boundaries and protect them.

5 Zodiac Signs You Don't Mess With

Virginia State

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Cheryl E Preston

Virginia fans of The Young and the Restless have asked where Elena Dawson (Brytni Sarpy) has been. She has not been seen or mentioned in Genoa City for quite a while. There is nothing online about Sarpy's status, and Y&R spoilers for next week do not mention the character, so fans wonder if she has been let go.

Fans of The Young and the Restless are concerned about Brtyni Sarpy and Conner Floyd's status

New research has identified crucial genes in broccoli that enhance its cancer-fighting compounds, promising healthier Brassica crop varieties. A comprehensive genomic analysis of broccoli has uncovered the genetic basis for producing glucosinolates (GSLs), substances known for their health advantages, such as anti-cancer properties. Researchers constructed a high-quality chromosome-level genome and pinpointed essential genes responsible for GSL synthesis. This research provides valuable knowledge for subsequent genetic research and the cultivation of Brassica crops with improved nutritional profiles, setting the stage for enhanced health benefits from these commonly eaten vegetables.

Scientists Crack the Code on Broccoli’s Health Benefits

Metabolic dysfunction-associated steatotic liver disease (MASLD)—the new name for non-alcoholic fatty liver disease (NAFLD)—and its more severe form, metabolic dysfunction-associated steatohepatitis (MASH), are responsible for a growing share of advanced liver disease. Linked to obesity and diabetes, fatty liver disease is increasingly recognized as a metabolic condition. Over...

Treatment for Fatty Liver Disease

Devra Lee

Disclaimer: This content was written by Devra Lee for general informational and entertainment purposes only. This service is to provide astrological information that has been researched, recorded, and observed by the author.

Horoscope for Friday, July 5th

Virginia fans of The Bold and the Beautiful, if you were watching earlier this week when Tom Star (Clint Howard died), you know that Li Finnegan (Naomi Matsuda) did not honor her Hippocratic Oath as a physician to "do no harm".

The Bold and the Beautiful shocker: Dr. Li Finnegan broke her Hippocratic Oath by watching Tom die

NewsBreak

New Study Links Gut Vitamin B Deficiency to Parkinson’s Disease

Nagoya University researchers found that deficiencies in gut bacteria genes for vitamins B2 and B7 are linked to Parkinson’s disease, suggesting that B vitamin supplementation could...

New Study Links Gut Vitamin B Deficiency to Parkinson’s Disease

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