Eli Lilly said it applied for U.S. approval of its weight loss drug Zepbound for the treatment of the most common sleep-related breathing disorder and expects regulators to make a decision as early as the end of the year. The company released additional data from two late-stage trials showing that...

Eli Lilly expects FDA decision on weight loss drug Zepbound for sleep apnea as early as end of the year

Shares of the pharmaceutical companies Novo Nordisk and Eli Lilly slid down Wednesday (July 17) after Roche announced results from its promising early-stage trial for its proposed obesity drug. It is understood that the drugmaker recently acquired Carmot Therapeutics and that its drug candidate garnered positive results, which would escalate...

Novo Nordisk, Eli Lilly Shares Decrease After Roche Reveals Obesity Drug Trial

Shares of Eli Lilly & Co. (NYSE:LLY) and Novo Nordisk (NYSE:NVO) are down 3% and 4.2%, respectively, on Wednesday after Roche announced positive Phase 1 results of its oral GLP-1 receptor agonist CT-996 for the treatment of people with obesity. The company said data showed that treatment with CT-996 in...

Eli Lilly, Novo Nordisk fall as Roche's rival weight loss drug shows promise

A closely watched obesity pill being developed by Roche helped people in a small Phase 1 trial lose 7.3% of their body weight over four weeks when taken once daily — 6.1 percentage points more than those given a placebo, the company said Wednesday. The data comes two months...

Obesity pill from Roche shows promising weight loss in small study

The Independent

 A new weight loss drug is more effective than medications such as Ozempic and Wegovy, new research suggests.Tirzepatide, which is sold under the brand names Mounjaro and Zepbound – which treat diabetes and weight loss, respectively – leads to more weight loss than semaglutide.Semaglutide is the active ingredient in Novo Nordisk’s Wegovy and Ozempic, which have been taken for weight loss by an estimated 15.5 million Americans, according to a Gallup poll released in May.A new study, published Monday in JAMA Internal Medicine, is thought to be the first head-to-head comparison of the two weight loss drugs.Electronic health records...

A weight loss miracle! New shot does better than Ozempic and Wegovy during trials

Metformin, a medication commonly used to treat type 2 diabetes, helps the body regulate sugar in the bloodstream. Part of the class of drugs known as biguanides, metformin reduces the amount of sugar you absorb from food and the amount produced by the liver. Metformin also impacts the way the body will respond to insulin, the natural substance that regulates blood sugar levels.

Diabetes Drug Metformin Investigated for Cancer Prevention Use

Semaglutide drugs like Ozempic and Wegovy seemingly exploded onto the scene in the past couple of years. But the drug has been around longer than that. Under the brand name Ozempic, semaglutide was approved by the U.S. Food and Drug Administration (FDA) in 2017 to help people with type 2 diabetes manage their blood sugar. In 2021, it was FDA-approved under the brand name Wegovy to help those with overweight and obesity lose weight.

How Long Have Semaglutide Drugs Like Ozempic and Wegovy Been Around?

Everyday Health

Now in clinical trials, this new medication can lead to impressive weight loss while preserving more lean muscle than its rivals.

Is This Drug the Next Ozempic?

New York Post

Lexapro, Paxil and Cymbalta carry a higher risk of packing on pounds than Zoloft, while Wellbutrin users are less likely to gain weight, according to a new study of eight popular antidepressants.

Harvard Pilgrim Health Care Institute (HPHCI) researchers analyzed the weights of more than 183,000 adult antidepressant users six months, a year and two years after they started taking the drugs.



Data from taking Celexa (citalopram), Lexapro (escitalopram), Prozac (fluoxetine), Paxil (paroxetine), Wellbutrin (bupropion), Cymbalta (duloxetine) and Effexor (venlafaxine) was compared to Zoloft (sertraline), which is the most prescribed antidepressant in the US.

At six months, Lexapro, Paxil and Cymbalta users were...

These popular antidepressants cause the most weight gain: Harvard research

New York City, NY

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Cheryl E Preston

Yesterday was the third time this year that an ad stating Chelsea Clinton lives in a beautiful Virginia home popped up on my laptop. My computer did not warn me this was a dangerous site, so this time, I clicked on the link.

Chelsea Clinton is rumored to be living in Virginia but probably still in NYC

ScienceAlert

Semaglutide, the active ingredient in brand medicines like Ozempic and Wegovy, could raise the risk of a relatively rare eye disease that is a leading cause of vision loss, according to a retrospective study. The research was led by scientists at Harvard University, and it was driven by anecdotal reports...

Ozempic-Like Drugs 'Tentatively' Linked With Sudden Vision Loss Risk

Denver, CO

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David Heitz

A dangerous drug that is being mixed into fentanyl is causing those who inject it to develop a rash of sores that resembles a case of flesh-eating bacteria. People experiencing homelessness around Denver can sometimes be seen with these bloody, weeping wounds. I recently mentioned this phenomenon to a fentanyl user who told me about the xylazine connection.

Denver homeless people suffer sores as xylazine enters fentanyl supply

SurvivorNet

A mother of two experiencing bloating and blood in her stool was told her worrisome symptoms could be a vitamin D deficiency or irritable bowel syndrome (IBS). However, a colonoscopy revealed she had stage 4 bowel (colorectal) cancer. Treatment, including chemotherapy and surgery, helped her reach remission.

‘I’m in Pain Constantly’ — A 37-Year-Old Mom of 2 With Bloating, Blood in Stool Told IBS May Be the Issue, Instead She Learned It Was Stage 4 Cancer

UPI News

A new monoclonal antibody treatment called Kesimpta (ofatumumab) appears to improve on an older drug in pushing multiple sclerosis (MS) into remission, a new trial shows.

New drug shows promise at sending MS into remission

Novo Nordisk’s massively successful GLP-1 analog semaglutide, the active ingredient in the popular diabetes and obesity meds Ozempic and Wegovy, may be linked to a vision loss disorder, a new study suggests. But one team of analysts cautioned against reading too much into the analysis. The study found that...

Novo's Ozempic, Wegovy linked to potential eye problem? Not so fast, analysts say

Isle Of Palms, SC

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The Shy Green

In a recent twist for spirits enthusiasts, Never Forget Brands, the creators of GameDay Vodka and Spiked canned vodka cocktails, have officially filed for Chapter 11 bankruptcy. Based in Isle of Palms, South Carolina, the distillery cited mounting financial pressures and substantial debts owed to various entities, including notable NFL teams and entertainment partners.

Vodka Maker Files for Bankruptcy Amid Financial Struggles

(HealthDay News) — Glucose lowering by metformin is greater when given before enteral glucose among patients with type 2 diabetes controlled by metformin monotherapy, according to a study recently published in Diabetologia. Cong Xie, PhD, from the University of Adelaide in Australia, and colleagues studied 16 participants with type...

Timing of metformin important in metformin-treated type 2 diabetes

GLP-1 medications like semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and tirzepatide (Mounjaro, Zepbound) are making headlines in type 2 diabetes, but people with type 1 diabetes (T1D) are taking these medications, too. No, these medications are not approved by the U.S. Food and Drug Administration (FDA) for T1D, but nonetheless many people are taking them off-label with the full approval of their doctors.

Why We Take Ozempic for Type 1 Diabetes

Parade

What You Should Never, Ever Do if You Get a Hepatitis C Diagnosis, Doctors Warn

Hamilton Township, NJ

NewsByJoshua

Rainbow Shops, a popular clothier known for its youth clothing, is preparing to shut down its location at the Hamilton Mall in Hamilton Township, New Jersey. The store is currently offering a hefty 40% discount on all items as part of its liquidation sale.

Popular Clothing Store Offers Offers Deep Discounts, Closing 950 Locations in Struggling Mall

NewsBreak

Pfizer Moves Forward With Once-Daily Weight-Loss Pill

(Reuters) -Pfizer plans to move a reworked, once-a-day version of its weight-loss pill danuglipron into clinical trials later this year, the company said on Thursday, after...

Pfizer Moves Forward With Once-Daily Weight-Loss Pill

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