Developed by Vertex Pharmaceuticals, suzetrigine is a promising new class of pain medicine that has been gaining attention for its innovative mechanism of action and reported efficacy; suzetrigine might offer hope for those struggling with acute pain issues who want to avoid opioids and NSAIDs. The reliance on opioids and...

A New Class of Medicine for Pain Relief On The Horizon

Institute for Bioengineering of Catalonia (IBEC) Light can be used to activate drugs in specific parts of the body through photopharmacology. This innovative approach involves modifying the chemical structure of a drug by adding a light-activated molecular switch, such as azobenzene. This allows the drug to be activated only when exposed to a specific colour of light, rather than in the dark.

Light-activated drugs against neuropathic pain

A team of researchers from the Institute for Bioengineering of Catalonia (IBEC) has developed light-activated derivatives of the anti-epileptic drug carbamazepine to treat neuropathic pain. Light can be harnessed to target drugs to specific body areas using photopharmacology. This technique modifies the drug’s chemical structure by incorporating a light-sensitive molecular...

Innovative Light-Controlled Drugs Could Revolutionize Neuropathic Pain Treatment

Over thirty years as a physician, I have proudly and intentionally developed my subspecialty in pain management. As an interventional physiatrist, it is my chosen calling to improve the quality of life of people in pain and help them get moving again. I’ve had the privilege of overseeing many remarkable recoveries, including those by patients who had little hope when they first came to my office. Though this has been enormously satisfying, I’ve noticed a troubling trend in recent years.

30 years in pain management: Transforming lives beyond opioids

While each decade has its own television shows that leave a mark, the 1980s was full of some truly great comedy television. It was the era when we first met Michael J. Fox as Alex P. Keaton on Family Ties. We met the Tanners on Full House and the Seavers on Growing Pains. Then, there was Cheers, The Golden Girls, The Cosby Show, Family Matters, and Silver Spoons. And we can’t forget about iconic shows like Miami Vice, Roseanne, Murder, She Wrote, and Unsolved Mysteries.

Beloved Child Actor, 46, Found Dead Alongside Service Dog

On July 6, 2020, 58-year-old Mary Kay Letourneau died of colon cancer — with her former student and husband Vili Fualaau by her side. When Mary Kay Letourneau died in 2020, most headlines eulogized her in the same way: as a teacher who raped and later married her former student. Indeed, Letourneau is best known for her relationship with Vili Fualaau, which started in 1996 when she was 34 and he was 12.

The Death Of Mary Kay Letourneau, The Teacher Who Raped Her Sixth-Grade Student — And Later Married Him

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NewSantaAna

The FBI has seen a rise in scams targeting timeshare owners. In this kind of scam, criminals con these part-time property owners into shelling out hefty sums of cash, all under false pretenses related to their timeshare properties.

FBI warns that Mexican cartels are targeting Americans with timeshare scams

BroBible

Some villages in Colombia are facing uncertain economic times due to a problem that they have never had deal with before: too much cocaine. According to a new report by the New York Times (via Yahoo News), the small, remote Colombian village of Cano Cabra has shrunk from 200 residents down to just 40 because […]
The post Colombia Facing Economic Crisis Caused By The Production Of Too Much Cocaine appeared first on BroBible.

Colombia Facing Economic Crisis Caused By The Production Of Too Much Cocaine

Alabama State

Blount County, AL

The Independent

An Alabama mother has been sentenced to decades behind bars after she left her toddler with her abusive partner, only for her to stop for cigarettes on the way to the hospital, where he died days later.Samantha McCormack, 30, was sentenced by a Blount County judge to serve 25 years in a state correctional facility in connection to the killing of her 18-month-old son, Enzo McCormack, five years ago.She had previously pleaded guilty to felony murder during the course of child abuse.Her partner at the time, 32-year-old Robert Keith Elmore Jr, has already been convicted in 2023 of capital murder...

An Alabama mom stopped to buy cigarettes while driving her dying son to ER. Now she’ll spend decades behind bars for his death

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Ms Trent

Disclaimer: Ms. Trent's content is intended for general information and entertainment. The astrological information presented has been extensively researched, meticulously recorded, and carefully observed by the author.

This is the most hypochondriac Zodiac sign

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Emily Standley Allard

Marriage is a significant life decision that requires extreme commitment, understanding, devotion and a heck of a lot of compromise. While many people dream of a lifelong partnership, others find the concept of marriage challenging. Astrology offers insights into personality traits and behaviors, suggesting that certain zodiac signs might face more difficulties in maintaining a traditional marital relationship. This article explores the five zodiac signs that are often considered less suited for marriage due to their unique characteristics and tendencies when it comes to lifelong commitment.

The 5 Zodiac Signs Not Meant for Matrimony

Halis Akturk, MD, offers an overview of the growing prevalence and dangers associated with cannabis use among patients with type 1 diabetes. Despite medical cannabis in the US dating back more than 3 decades, the legalization movement in the last decade means millions and millions of US adults now have access to cannabis, for both medical and recreational purposes.

What to Know About Cannabis Use and Diabetes, with Halis Akturk, MD

Ozzy Osbourne sparked further concerns as his health has reportedly taken a turn for the worse. The Prince of Darkness, 75, has been battling health issues over the years. After his canceled appearance at the Mad Monster Party, sources revealed to In Touch what reportedly kept him away from the gig.

Ozzy Osbourne's Health Has Worsened: Rocker Now Suffering End Stages of Parkinson's— Report

Wide Open Country

I Dream of Jeannie star Barbara Eden endured years of rumors that she and Elvis Presley actually had a fling. However, she finally put it to bed 64 years later. The two worked together on a movie, Flaming Star, together and became friends. However, she and Presley never had any romantic interest in each other. At the time, Eden was married to actor Michael Ansara. Meanwhile, Presley had a love for himself — his future wife Priscilla.

‘I Dream of Jeannie’ Star Barbara Eden Finally Addresses Those Elvis Romance Rumors 64 Years Later

Upworthy

If you're one of the more than 53 million individuals dealing with arthritis pain, you may benefit from adding CBD to your pain management plan. CBD is growing popular among Americans seeking to manage moderate to chronic pain, and for many, it's become part of their daily regimen.While CBD may not be the end-all for your arthritis pain, it can provide some discomfort relief and may even offer additional wellness benefits like reduced stress, relaxation, and improved sleep. If you're curious about this cannabinoid’s pain-relieving properties, check out our top choices for the best CBD for joint pain.Best CBD Products...

Best CBD for joint pain: 5 CBD products to relieve pain and inflammation

Total Apex Sports & Entertainment

Do your loved ones consult you regularly when they face a crisis? Intelligence is a branch of psychology that lacks a standard definition. Some scientists claim that it is a single ability and others state it comprises aptitudes and skills. Intelligent zodiac signs learn from their experiences and easily recognize and solve problems.

5 Most Intelligent Zodiac Signs

Health

Medically reviewed by Robert Burakoff, MDMedically reviewed by Robert Burakoff, MDHeartburn is a burning sensation in your chest caused by stomach acid refluxing (coming back up)  into the esophagus (the hollow muscular tube that connects your throat to your stomach). Over 60 million Americans experience heartburn at least once a month.You may experience heartburn every once in a while from overeating or eating too fast. Some people get occasional heartburn, but some experience it more regularly if they have a condition like gastroesophageal reflux disease (GERD) or chronic acid reflux.GERD is a gastrointestinal condition in which stomach acid flows...

What To Drink for Heartburn Relief

Many try to find reasons to skip work for a day or two but rarely get away with it. But one man stunned people by not turning up for work for at least six years. No one knew about it until he was due to be awarded for 20 years of loyalty and dedicated service, reported The Guardian. The incident that came to light in 2010 involved a man named Joaquin Garcia, a 69-year-old engineer in Spain, who was working for the local government.

Man skips work for six years and goes unnoticed until employers decide to honor his long service

Chicago, IL

Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

What makes a zodiac sign high maintenance? Needing extra attention can make someone high maintenance. Uncontrollable emotional roller coasters can make someone high maintenance. Demanding others more than they can give can make someone high maintenance. Needing all of the attention all or most of the time can make someone high maintenance.

5 Zodiac Signs That Are High Maintenance

NewsBreak

Cannabis terpenes offer new hope for neuropathic pain relief

Chronic pain, particularly neuropathic pain resulting from nerve damage, significantly impacts quality of life for many individuals. Conventional treatments, such as opioids, often come with severe...

Cannabis terpenes offer new hope for neuropathic pain relief

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