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Long COVID is a brutal illness without a known mechanism or cure. Far from being psychosomatic in nature, a new study adds weight to the idea that this misunderstood disease is very much biological.
The lingering toll the SARS-CoV-2 virus exacts on the immune system is widespread and hiding in plain sight, argue researchers at the University of California, San Francisco, CellSight Technologies, and Kaiser Permanente South San Francisco Medical Center.
When 24 patients who had recovered from COVID-19 had their whole bodies scanned by a PET (positron emission tomography) imaging test, their insides lit up like Christmas trees.
A radioactive drug called...

COVID's Hidden Toll: Full-Body Scans Reveal Long-Term Immune Effects

Early on during the coronavirus pandemic, there were reports of cases of persistent post-infection symptoms. The World Health Organization (WHO) refers to such new or persistent symptoms twelve weeks after a corona infection that cannot be explained by other causes as a post-COVID-19 condition. In a recent study, scientists led by the University Medicine Halle evaluated the information from 109,707 participants in the German National Cohort (NAKO Gesundheitsstudie) on their self-reported health status with respect to post-infection symptoms. The survey took place in autumn 2022, in retrospect of the pandemic.

Study on post-COVID-19 condition: Which factors have an impact on the risk

Medical News Today

A new study reveals a link between gut microbiota and Parkinson's disease, finding that people may have fewer bacteria that produce riboflavin (vitamin B2) and biotin (vitamin B7).

Study suggests 2 vitamin B deficiencies may play a role in Parkinson's disease

A recent study conducted by a team of medical researchers from the University of California, San Francisco, and CellSight Technologies has revealed intriguing findings about long COVID. The researchers discovered that certain patients with long COVID exhibit unusual behavior in their immune cells in multiple organs, with some still having...

Long COVID Patients Have Traces Of SARS-CoV-2 RNA For Up To Two Years After Their Initial Infection

Bronchitis is acute (sudden onset and temporary) or chronic (ongoing) inflammation of the bronchi. The bronchi are the large tubes that carry air from the trachea to the lungs. The inflammation triggers a cough that often produces mucus. Many people wonder if bronchitis is contagious. Technically, the answer is no....

How Bronchitis Inflammation Affects Breathing

rolling out

Managing glucose levels is crucial for maintaining overall health, but many people are unaware of the joint pains associated with glucose health issues. These pains can range from mild discomfort to severe, life-altering conditions. Understanding these pains, their causes, and how to manage them is essential for anyone with glucose-related health problems.

Common pains linked to glucose health issues

Review the multiple uses of metformin. A recent article on the multiple uses of metformin brings up the important topic of repurposing medications.1 Repurposing has been around since the advent of modern medicine. One prominent example is the use of chlorpromazine (CPZ) as an antipsychotic.2 Chlorpromazine was first synthesized in 1951 as a potentiator of general anesthesia.2 The psychiatric benefits were found later by Henri Laborit, a surgeon in the French army. He was doing research with artificial hibernation in prevention of surgical shock.2 Laborit employed the drug as an adjunct to anesthetics.2 He observed that CPZ at doses of 50 mg to 100 mg produced a lowering of body temperature, sedation, and disinterest without loss of consciousness.2 He was able to persuade his colleagues in the military hospital in Paris to try CPZ in the treatment of one of their patients who was experiencing psychotic agitation.2 Laborit hypothesized that since cooling with water had been used to treat agitation in France, the drug would have a similar effect.2 The mechanism of action was not fully known, and it was thought that it worked in controlling agitation because of its cooling effect and induction of “artificial hibernation” in patients.2 The pharmacological mechanism was not fully understood until many years later and the way it has impacted the practice of psychiatry needs no introduction. These “happy accidents” in medicine have played a vital role in getting where we are right now compared with just 50 years ago. This begs the question, are we onto another “happy accident” with metformin? There is an accumulating body of evidence that metformin may have benefits in aging that are beyond its effect on glycemic control.3.

Metformin, Inflammation, the Gut Microbiome, and Health Span: Connecting the Dots

Vitamin B12 deficiency is common. It can lead to various health issues, affecting everything from energy levels to brain function. Vitamin B12, or cobalamin, is an essential nutrient in meat, fish, and dairy products. It is crucial for red blood cell production and a healthy nervous system. When B12 levels...

Unusual symptoms of B12 deficiency

Health

Reviewed by Ivy Kwong, LMFTReviewed by Ivy Kwong, LMFTIrritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) are two chronic gastrointestinal disorders that share some overlapping symptoms, like abdominal pain, bloating, and diarrhea. While IBS and IBD have similar symptoms and acronyms, they are two distinct conditions with different underlying causes and treatment approaches. IBS is a functional disorder, meaning it affects how the intestines work but doesn't cause inflammation. IBD is an inflammatory disease that damages the gastrointestinal (GI) tract. In the United States, IBS affects between 25-45 million people, and IBD affects more than 3 million people.Symptoms of IBS vs....

What Is the Difference Between Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD)?

Diabetic neuropathy can worsen over a period of many years. If it continues to progress, it can lead to potentially serious complications. Managing your blood sugar can help slow progression, especially for type 1 diabetes. Untreated diabetes can lead to a range of complications. These include damage to the nerves...

Diabetic Neuropathy Progression: What to Know

The following is a summary of “Dopamine signaling enriched striatal gene set predicts striatal dopamine synthesis and physiological activity in vivo,” published in the April 2024 issue of Psychiatry by Sportelli et al. The genetic basis of schizophrenia involves multiple pathways related to synaptic function, but how these...

Understanding Brain Dopamine Pathways and Schizophrenia Genetics

A study reveals a new mechanism where proteins released during migraine auras are transported to sensory nerves, triggering migraines, which could lead to innovative treatments. This discovery explains the one-sided nature of migraines and identifies potential new protein targets for therapies. A new study has uncovered a previously unidentified process...

Breakthrough Study Reveals Hidden Mechanism Behind Migraines

Fever with thrombocytopenia is usually due to an infection, often from mosquito or tick bites. Treating the infection typically resolves thrombocytopenia, but certain infections may have a less favorable outlook. Platelets are tiny cell fragments that make up the blood. Also known as thrombocytes, they help form clots that stop...

What Causes Fever with Thrombocytopenia (Low Platelets)?

LSDs affect about one in 7,700 live births worldwide. Children with the condition typically present at a young age with progressive neurodegeneration. Many children with LSDs die prematurely, and current treatments focus on symptom management. Until now, the role of macrophages in the immune system and LSDs was not well...

Immune Cell Inflammation Responsible for Severe Symptoms in Rare Neurodegenerative Disease

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Total Apex Sports & Entertainment

There are certain zodiac signs that most people are careful with because of their fiery and low tolerance levels. You can hardly mess with individuals with such signs without getting a backlash. Whether they are in work environments or family settings, they do not hesitate to set boundaries and protect them.

5 Zodiac Signs You Don't Mess With

Woman's World

For all women, estrogen is essential for sustaining the hair growth phase and boosting hair density on the scalp. But owing in large part to genetics, the follicles of some women are particularly dependent on the hormone, says endocrinologist Geoffrey Redmond, MD. This means even slight declines can set off shedding. And for women whose follicles rely heavily on estrogen, problems tend to crop up around perimenopause, when the hormone breaks its predictable monthly pattern and begins a downward trend.

Low Estrogen Levels Can Be Linked To Thinning Hair: Here’s What Can Help

Chicago, IL

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Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

Kentucky State

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Northern Kentucky Tribune

Kentucky’s Community Actions Partnerships have announced the starts date for the Low-Income Home Energy Assistance Program (LIHEAP) Summer Subsidy, aimed at helping Kentucky households offset summer cooling costs.

LIHEAP Summer Subsidy program to help with summer cooling costs to begin enrollment July 16

Oregon State

NewsByJoshua

With scorching heatwaves sweeping across the country, drivers are being advised to take their car's thermometer readings with a grain of salt. While your dashboard might display a temperature that seems outrageously high, experts suggest not relying on it for an accurate outdoor temperature gauge.

Drivers cautioned not to use a standard car feature on hot days - opt for your phone instead

Denver, CO

David Heitz

A dangerous drug that is being mixed into fentanyl is causing those who inject it to develop a rash of sores that resembles a case of flesh-eating bacteria. People experiencing homelessness around Denver can sometimes be seen with these bloody, weeping wounds. I recently mentioned this phenomenon to a fentanyl user who told me about the xylazine connection.

Denver homeless people suffer sores as xylazine enters fentanyl supply

NewsBreak

SARS-CoV-2 infections have a long-term impact on the immune system

In a study recently published in the renowned journal Allergy, a MedUni Vienna research team shows that COVID-19 leads to considerable long-term changes in the immune...

SARS-CoV-2 infections have a long-term impact on the immune system

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