ScienceAlert

A newly discovered communication pathway linking far-flung nerve centers within the brain and skull, and the body beyond, could provide a new target to stop migraine pain in its tracks. Researchers have long tried to pinpoint where migraines begin in the brain, and how these one-sided, nauseating headaches induce pain...

A New Pathway Found in The Brain Could Help Spell The End of Migraines

Researchers know that genetics play a role in obesity. Scientists from the University of Exeter Medical School have found that people missing a specific blood group due to a genetic variant may be genetically predisposed to having obesity or overweight. Researchers believe these people missing the SMIM1 gene may be...

Missing a specific blood group may genetically predispose people to obesity

Summary: Researchers discovered how the protein CGRP affects the brain’s lymphatic system, contributing to migraine pain. Their study reveals that CGRP prevents cerebrospinal fluid from draining, influencing migraine attacks. This finding could lead to new therapeutic strategies for migraines. More research is needed to understand the sex differences in...

Brain’s Lymphatic System Plays Role in Migraine Pain

Infections and neurodegenerative diseases cause inflammation in the brain. But for unknown reasons, patients with brain inflammation often develop muscle problems that seem to be independent of the central nervous system. Now, researchers at Washington University School of Medicine in St. Louis have revealed how brain inflammation releases a specific protein that travels from the brain to the muscles and causes a loss of muscle function.

Brain inflammation triggers muscle weakness after infections

Summary: A new study identifies beta frequency neural activity in the anterior cingulate cortex (ACC) as crucial for recognizing rewards and shaping behavior. This neural signature is altered in patients with depression, suggesting it could serve as a biomarker and potential treatment target for anhedonia. The research highlights how brain...

Beta Brain Waves: A Novel Brain Signature for Depression

Broken heart syndrome is also known as stress cardiomyopathy or takotsubo syndrome. Symptoms are similar to a heart attack and occur when a person experiences severe emotional or physical stress. When an individual has a stressful life event, they may experience something known as broken heart syndrome, a temporary heart...

Broken heart syndrome: Pictures and more

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Total Apex Sports & Entertainment

There are certain zodiac signs that most people are careful with because of their fiery and low tolerance levels. You can hardly mess with individuals with such signs without getting a backlash. Whether they are in work environments or family settings, they do not hesitate to set boundaries and protect them.

5 Zodiac Signs You Don't Mess With

Chicago, IL

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Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

What makes a Zodiac Sign low maintenance? Independence can make someone low maintenance. Someone who is reliable, dependable, and punctual, can make someone low maintenance. Someone who tends to want to do things on their own can be low maintenance. Low-maintenance people tend to be those people who do on their own but are not necessarily alone. They rarely need or ask for help. They are self-motivated, often energetic, and can be considered leaders is many cases. Now me, some say I am low maintenance and others say I’m high maintenance. Maybe I’m both. Let's see what zodiac signs are considered low-maintenance.

5 Zodiac Signs That Are Low Maintenance

Nagoya University researchers found that deficiencies in gut bacteria genes for vitamins B2 and B7 are linked to Parkinson’s disease, suggesting that B vitamin supplementation could be a potential treatment. A study conducted by the Nagoya University Graduate School of Medicine in Japan has discovered a connection between gut...

New Study Links Gut Vitamin B Deficiency to Parkinson’s Disease

Review the multiple uses of metformin. A recent article on the multiple uses of metformin brings up the important topic of repurposing medications.1 Repurposing has been around since the advent of modern medicine. One prominent example is the use of chlorpromazine (CPZ) as an antipsychotic.2 Chlorpromazine was first synthesized in 1951 as a potentiator of general anesthesia.2 The psychiatric benefits were found later by Henri Laborit, a surgeon in the French army. He was doing research with artificial hibernation in prevention of surgical shock.2 Laborit employed the drug as an adjunct to anesthetics.2 He observed that CPZ at doses of 50 mg to 100 mg produced a lowering of body temperature, sedation, and disinterest without loss of consciousness.2 He was able to persuade his colleagues in the military hospital in Paris to try CPZ in the treatment of one of their patients who was experiencing psychotic agitation.2 Laborit hypothesized that since cooling with water had been used to treat agitation in France, the drug would have a similar effect.2 The mechanism of action was not fully known, and it was thought that it worked in controlling agitation because of its cooling effect and induction of “artificial hibernation” in patients.2 The pharmacological mechanism was not fully understood until many years later and the way it has impacted the practice of psychiatry needs no introduction. These “happy accidents” in medicine have played a vital role in getting where we are right now compared with just 50 years ago. This begs the question, are we onto another “happy accident” with metformin? There is an accumulating body of evidence that metformin may have benefits in aging that are beyond its effect on glycemic control.3.

Metformin, Inflammation, the Gut Microbiome, and Health Span: Connecting the Dots

Verywell Health

A recent study found people with carpal tunnel syndrome tend to develop cardiac amyloidosis, also known as “stiff heart syndrome,” about 10 to 15 years later. Experts say the presence of carpal tunnel syndrome may be an early warning sign for cardiac amyloidosis, as amyloid deposits can affect both the wrist’s connective tissue and the heart.

Carpal Tunnel Syndrome May Triple Your Risk of Developing Stiff Heart Syndrome

Cardiovascular-kidney-metabolic (CKM) syndrome (CKM) describes the complex health disorder caused by connections between diabetes, obesity, heart disease, and kidney disease. Preventing CKM syndrome involves maintaining a healthy body weight, eating healthy foods and being physically active. Taking medications to manage blood sugar, blood pressure, and cholesterol may be necessary. By...

What Is CKM Syndrome? Causes, Treatments, and Prevention

The following is a summary of “Dopamine signaling enriched striatal gene set predicts striatal dopamine synthesis and physiological activity in vivo,” published in the April 2024 issue of Psychiatry by Sportelli et al. The genetic basis of schizophrenia involves multiple pathways related to synaptic function, but how these...

Understanding Brain Dopamine Pathways and Schizophrenia Genetics

The ovaries are involved in far more than just reproduction. The two oval-shaped glands that float on either side of the uterus don't just produce and release eggs, they also pump out hormones that help keep a person's heart, bones, brain, and immune system healthy as they age. A new...

Losing Both Ovaries Could Come at a Serious Cost to The Brain, Researchers Find

Devra Lee

Disclaimer: This content was written by Devra Lee for general informational and entertainment purposes only. This service is to provide astrological information that has been researched, recorded, and observed by the author.

Horoscope for Tuesday, July 16th

Vitamin B12 deficiency is common. It can lead to various health issues, affecting everything from energy levels to brain function. Vitamin B12, or cobalamin, is an essential nutrient in meat, fish, and dairy products. It is crucial for red blood cell production and a healthy nervous system. When B12 levels...

Unusual symptoms of B12 deficiency

rolling out

Managing glucose levels is crucial for maintaining overall health, but many people are unaware of the joint pains associated with glucose health issues. These pains can range from mild discomfort to severe, life-altering conditions. Understanding these pains, their causes, and how to manage them is essential for anyone with glucose-related health problems.

Common pains linked to glucose health issues

A recent preclinical study found that supplementation with a branded pomegranate extract called Pomanox, from Euromed, may support liver health and alleviate fructose-induced metabolic impairment. A recent preclinical study1 found that supplementation with a branded pomegranate extract (Pomanox from Euromed based in Mollet del Vallès, Spain) may support liver health...

Animal study finds that branded pomegranate extract may alleviate the impacts of fructose consumption on liver metabolism

T3D reveals a significant relationship between brain dysfunction and glucose levels, a critical factor in AD. Insufficient glucose levels can lead to an aggressive decline in insight, judgment, memory, and reasoning. Limited research reveals a link between Alzheimer’s disease and type 2 diabetes. Additional research is needed to understand...

What Is Type 3 Diabetes?

NewsBreak

Obesity Gene Influences Brain Activity

Summary: Researchers have identified the SH2B1 gene’s crucial role in regulating food intake and energy expenditure. Mutations in SH2B1 are linked to obesity, type 2 diabetes,...

Obesity Gene Influences Brain Activity

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