ScienceAlert


Researchers have discovered how a cell surface protein called Aplp1 can play a role in spreading material responsible for  Parkinson's disease from cell-to-cell in the brain.
Promisingly, an FDA-approved  cancer drug that targets another protein called Lag3 – which interacts with Aplp1 – blocks the spread in mice, suggesting a potential therapy may already exist.



					
			

In a new paper, an international team of scientists describes how the two proteins work together to help harmful alpha-synuclein protein clumps get into brain cells.
"Now that we know how Aplp1 and Lag3 interact, we have a new way of understanding how alpha-synuclein contributes to...

Parkinson's Discovery Suggests We May Already Have an FDA-Approved Treatment

Medical News Today

A new study reveals a link between gut microbiota and Parkinson's disease, finding that people may have fewer bacteria that produce riboflavin (vitamin B2) and biotin (vitamin B7).

Study suggests 2 vitamin B deficiencies may play a role in Parkinson's disease

Visual hallucinations are a significant issue for many patients with Parkinson’s disease. A recent study published in the journal Brain reveals that these hallucinations are associated with a marked deficiency of cholinergic activity in specific regions of the brain, particularly the left ventral visual stream and the left superior temporal lobe. This research highlights the importance of cholinergic denervation in visual hallucinations, offering new insights into the underlying mechanisms and potential treatment options.

Visual hallucinations in Parkinson’s disease linked to cholinergic deficiency

Parkinson’s disease may make people feel exhausted and make it difficult to concentrate. This can make everyday tasks more challenging. Many people with Parkinson’s disease (PD) experience fatigue. Motor symptoms can make it difficult and tiring to carry out everyday tasks. PD medications may also cause drowsiness. Problems with sleep and depression are also.

What to know about Parkinson’s fatigue

TIME

After a specialist visited the White House, speculation about Joe Biden's health swirled. Here's how Parkinson's is actually diagnosed.

How Is Parkinson’s Disease Diagnosed?

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Total Apex Sports & Entertainment

Do your loved ones consult you regularly when they face a crisis? Intelligence is a branch of psychology that lacks a standard definition. Some scientists claim that it is a single ability and others state it comprises aptitudes and skills. Intelligent zodiac signs learn from their experiences and easily recognize and solve problems.

5 Most Intelligent Zodiac Signs

You may be able to tell a lot about your health from how often you poop. “In the scientific literature, we see strong associations between bowel movement frequency abnormalities (constipation, in particular) and chronic diseases, like neurodegeneration and chronic kidney disease,” Dr. Sean Gibbons, associate professor at the Institute for Systems Biology in Seattle, tells TODAY.com in an email.

How many times a day you poop can tell you a lot about your long-term health, study finds

A recent study conducted by researchers at Kobe University Graduate School of Medicine, and published in the Journal of Psychiatric Research, reveals compelling evidence that alcohol dependence accelerates biological aging. By examining various epigenetic markers, the researchers found that individuals with alcohol dependence showed accelerated aging processes, which decelerated after a three-week treatment program.

Alcoholism is associated with accelerated biological aging

What makes a zodiac sign high maintenance? Needing extra attention can make someone high maintenance. Uncontrollable emotional roller coasters can make someone high maintenance. Demanding others more than they can give can make someone high maintenance. Needing all of the attention all or most of the time can make someone high maintenance.

5 Zodiac Signs That Are High Maintenance

Fox News

Neurologist Dr. Tom Pitts told NBC News Now that President Biden shows visual symptoms of Parkinson's disease, "one of the easier movement disorders to diagnose."

Neurologist says Biden displays 'hallmark' symptoms of Parkinson's: 'Not a hard case' to diagnose

Few things are worse than being cheated on, but the fear that your partner might be unfaithful can be just as tough. That nagging uncertainty can keep you up at night and make you second-guess everything—all while slowly chipping away at the trust in your relationship. Thankfully, psychological research...

11 Signs That Your Partner Might Be Cheating On You

Insider

Dr. Michael Roizen, the chief wellness officer at Cleveland Clinic, shared how he eats to stay young, including following the Mediterranean diet.

A 78-year-old doctor says he's reversed his age by 20 years. Here are the 4 diet principles he follows to stay young.

Research indicates that getting too little or too much sleep in later life is associated with a higher risk of developing Alzheimer's disease. The earliest affected brain regions in Alzheimer's are those involved in regulating sleep and circadian rhythms. This means that individuals in the early stages of the condition might experience sleep disturbances before showing the typical signs of memory loss or other symptoms.

Research States That Poor Sleeping Patterns In Older Adults Lead To Increased Risk Of Dementia

It seems intuitive. Older people need more medical surveillance for common diseases, as well as immunizations and other preventive measures. Well, intuition isn’t always reliable. Some common medical tests are not recommended after a certain age or when there are no symptoms. Some may even be harmful. After age...

Why certain health screenings may be unnecessary later in life

New York State

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Rootbound Homestead

Having survival supplies on hand before a disaster strikes will keep you out of the frantic ranks of the unprepared. I don't think I need to remind you all of the toilet paper crisis of 2020, or all the bread and milk that go first during large storms. With the current presidential situation, now is the time to start stocking up if you haven't already.

Prepare Now: Things That Will Disappear First From Store Shelves

shefinds

Parkinson’s disease is a progressive neurodegenerative disorder that affects millions of people worldwide. Characterized by tremors, stiffness, and difficulty with balance and coordination, the disease is primarily caused by the loss of dopamine-prod...

3 Supplements A Neuroscientist Swears By To Prevent Parkinson’s Disease: ‘Gives Your Brain The Raw Materials To Repair Itself’

Sleeping on the left side may worsen atrial fibrillation (AFib) symptoms for some people, but more research is necessary. The best sleeping position may depend on a person’s symptoms and individual health factors. The connection between sleeping position and AFib symptoms may come down to how different positions can...

What is the best sleep position for atrial fibrillation?

Rice is a staple food for more than half of the world’s population, cherished for its versatility and nutritional value. There are numerous varieties of rice, each offering different benefits. However, not all rice is created equal when it come...

3 Types Of Rice You Should Stop Eating To Avoid Inflammation—And 4 To Eat Instead: Avoid White Rice And More

Distractify

Of all the social media platforms, TikTok is known for its wacky trends, strange lingo, and, er, unique conspiracy theories. And now, users on TikTok want you to believe that your teachers are conspiring against you in a way that, for some reason, involves coded language.The theory that "homework" spelled backward means something sinister isn't new to the internet, but TikTok seems to be having a field day with it recently. With hundreds of videos shared on the topic, some of them pulling in over 2 million views each, this conspiracy seems to be spreading like wildfire. But is there...

TikTokers Allege That "Homework" Spelled Backward Means Something Sinister in Latin

Eli Lilly said it applied for U.S. approval of its weight loss drug Zepbound for the treatment of the most common sleep-related breathing disorder and expects regulators to make a decision as early as the end of the year. The company released additional data from two late-stage trials showing that...

Eli Lilly expects FDA decision on weight loss drug Zepbound for sleep apnea as early as end of the year

NewsBreak

What We Know About Coffee and Parkinson’s Disease

Research shows coffee-drinkers have a lower risk of developing Parkinson's disease. Studies find that caffeine may be a key ingredient that helps protect against Parkinson's. There...

What We Know About Coffee and Parkinson’s Disease

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