Protein ‘signatures’, which can be obtained via a blood sample, can be used to predict the onset of 67 diseases including multiple myeloma, non-Hodgkin lymphoma, motor neurone disease, pulmonary fibrosis, and dilated cardiomyopathy. Using protein information to predict the onset of diseases could help with timely diagnosis, early initiation of treatment and improved patient outcomes.

Blood Protein "Signatures" Predict Onset of 67 Diseases, Study Reveals

USC scientists have discovered a way to turn the body’s B cells into tiny surveillance machines and antibody factories that can pump out specially designed antibodies to destroy cancer cells or HIV, two of medicine’s most formidable foes. The research, published Monday in Nature Biomedical Engineering, describes a...

Researchers Turn B Cells Into Antibody Factories To Combat HIV and Cancer

A team of researchers from Penn State College of Medicine found a new target for treating diseases associated with human T-cell leukemia virus type 1 (HTLV-1). They determined that blocking a class of enzymes called kinases, which regulates cellular functions, leads to cell death caused by the degradation of Tax, a protein essential for viral gene expression, viral transmission and survival of cells infected by HTLV-1. The team published the findings in Nature Communications.

Drug Target Identified for Diseases Linked to Leukemia-Causing Virus

Researchers at the University of Kentucky have a better understanding of the regulation of extracellular vesicles by oxidative stress and how these vesicles spread oxidative stress and may damage neurons. Extracellular vesicles are nanoparticles released by all cell types that help transport information between cells. The study titled "Ceramide-mediated orchestration...

Study links nanoparticles to oxidative stress and neuron death

B12 is a vitamin that helps the body maintain essential systems, such as the central nervous system. A B12 deficiency in women can cause symptoms such as fatigue and more severe complications. The body needs B12 to function healthily, and a B12 deficiency can cause conditions such as severe neurological...

What are the symptoms of B12 deficiency in females?

San Francisco, CA

ScienceAlert


Long COVID is a brutal illness without a known mechanism or cure. Far from being psychosomatic in nature, a new study adds weight to the idea that this misunderstood disease is very much biological.
The lingering toll the SARS-CoV-2 virus exacts on the immune system is widespread and hiding in plain sight, argue researchers at the University of California, San Francisco, CellSight Technologies, and Kaiser Permanente South San Francisco Medical Center.
When 24 patients who had recovered from COVID-19 had their whole bodies scanned by a PET (positron emission tomography) imaging test, their insides lit up like Christmas trees.
A radioactive drug called...

COVID's Hidden Toll: Full-Body Scans Reveal Long-Term Immune Effects

Amyloid-beta (A-beta) aggregates are tangles of proteins most notably associated with neurodegenerative diseases such as Alzheimer’s. Despite its constant stint in the limelight, however, researchers have been unable to get a good understanding of how A-beta comes together and breaks apart. “The way A-beta behaves in a variety of...

Innovative Microscopy Reveals Structural Secrets of Amyloid Beta

A Japanese woman developed cold agglutination disease (CAD) following COVID-19 and a secondary bacterial infection in the lungs that may have worsened her symptoms, a case study showed. “There is a need for continuous observation to evaluate whether COVID-19, even when it does not require hospitalization, is related to the...

Lung infection likely triggered CAD after COVID-19: Case study

He explained in a video post, “The day after that I just went downhill [with a] swollen knee, although I thought that was because my knee was injured from a stack when I was in Hobart running some trails. “[I had] really bad body aches and sweat, and everything...

38-Year-Old Man’s Swollen Knee and Body Aches Led To Stage 4 Non-Hodgkin’s Lymphoma Diagnosis, Now He’s Urging Others To Get Symptoms Checked As Cancer ‘Doesn’t Discriminate’

LETM and AQP4-IgG seropositivity were strong predictors of spinal movement disorders, while MOG-IgG and African American race are protective factors. Recently published data from a prospective observational study revealed that spinal-generated movement disorders are highly prevalent in non-multiple sclerosis (MS) demyelinating disorders of the spinal cord and their prevalence rates were much higher than the rates reported in MS. Overall, the prevalence was highest in aquaporin-4-positive neuromyelitis optica spectrum disorder (AQP4+ NMOSD) and lowest in myelin oligodendrocyte glycoprotein antibody disorder (MOGAD).

Spinal Movement Disorders Prevalent in Non-MS Demyelinating Disorders of Spinal Cord

San Diego, CA

An unusually large brain may be the first sign of autism — and visible as early as the first trimester, according to a recent study conducted by UCSD. Some children with profound autism face lifelong challenges with social, language, and cognitive skills, including the inability to speak. In contrast, others exhibit milder symptoms that may improve over time.

Scientists Have Uncovered Autism’s Earliest Biological Signs

SurvivorNet

A healthy 38-year-old who began struggling to finish a half-marathon and experienced night sweats, body aches, and COVID-like symptoms learned he was facing stage 4 non-Hodgkin lymphoma. Despite the shocking diagnosis, he plans to remain positive while he fights the cancer.

Fit, Healthy Man, 38, With Swollen Knee Felt Covid-Like Symptoms for a Month Before Learning He Had Stage 4 Non-Hodgkin Lymphoma

Verywell Health

A recent study found people with carpal tunnel syndrome tend to develop cardiac amyloidosis, also known as “stiff heart syndrome,” about 10 to 15 years later. Experts say the presence of carpal tunnel syndrome may be an early warning sign for cardiac amyloidosis, as amyloid deposits can affect both the wrist’s connective tissue and the heart.

Carpal Tunnel Syndrome May Triple Your Risk of Developing Stiff Heart Syndrome

Kentucky State

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Northern Kentucky Tribune

Kentucky’s medical cannabis program has taken significant steps toward ensuring those with qualifying conditions have access to medical cannabis as soon as possible, said Gov. Andy Beshear this week.

State to open licensing applications for medical cannabis businesses beginning July 1

North Carolina State

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Town Talks

Death Disclosure Laws and Property Disclosures in North Carolina. In North Carolina, there is no legal obligation for homeowners or real estate agents to disclose if a death has occurred in a home, whether by natural causes, murder, or suicide. However, if a potential buyer directly inquires about any deaths on the property, the seller is required to provide that information.

If someone dies at your house do you have to tell a potential buyer? What North Carolina law says

The following is a summary of “Dopamine signaling enriched striatal gene set predicts striatal dopamine synthesis and physiological activity in vivo,” published in the April 2024 issue of Psychiatry by Sportelli et al. The genetic basis of schizophrenia involves multiple pathways related to synaptic function, but how these...

Understanding Brain Dopamine Pathways and Schizophrenia Genetics

Metabolic dysfunction-associated steatotic liver disease (MASLD)—the new name for non-alcoholic fatty liver disease (NAFLD)—and its more severe form, metabolic dysfunction-associated steatohepatitis (MASH), are responsible for a growing share of advanced liver disease. Linked to obesity and diabetes, fatty liver disease is increasingly recognized as a metabolic condition. Over...

Treatment for Fatty Liver Disease

Posted on Jul 05, 2024, 11 a.m. C15:0 deficiency is the first nutritional deficiency syndrome discovered in over 75 years. Low levels of C15:0, also called pentadecanoic acid, can result in fragile cells that can accelerate aging and increase the risk of developing chronic metabolic, heart, and liver conditions. According...

Cellular Fragility Syndrome May Explain Accelerated Aging In Young People

Healthline

Hard palate cancer is rare and forms on the roof of your mouth. Learn more.

What to Know About Hard Palate Cancer

Stage 3 laryngeal (throat) cancer is cancer that has spread beyond the larynx to nearby tissues, muscles, or lymph nodes but not to distant parts of the body. The term “stage” in the context of cancer refers to the extent or severity of cancer based on factors such as the size of the tumor, whether it has spread to nearby tissues, and whether it has spread to other parts of the body.

What is stage 3 laryngeal cancer?

NewsBreak

COVID-19 Causes a “Cell Death Cascade” in Airway Cells

Researchers Jenny Ting, PhD, the William Kenan Distinguished Professor of Genetics and professor microbiology and immunology at the UNC School of Medicine, and Kaixin Liang, PhD,...

COVID-19 Causes a “Cell Death Cascade” in Airway Cells

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