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Special Episode: FDA Approves Donanemab for Early Symptomatic Alzheimer Disease

Medical News Today

New research has found that a protein that regulates cell repair could be a promising new target for treating Alzheimer’s disease.

Study finds possible new target for early treatment of Alzheimer's disease

The Mirror US

Although there is currently no known cure for Alzheimer's, there are treatments that can lessen its symptoms, including disorientation and memory loss, and some may even stop the disease's progression

New Alzheimer's treatment could reverse brain disease and restore memory, study finds

The early signs of dementia in women include memory loss and confusion. Dementia is a collective term that describes various symptoms of cognitive decline, such as forgetfulness, confusion, and changes in behavior. It is not a specific disease but a group of conditions characterized by impairment of at least two brain functions, such as memory loss and judgment.

Early signs of dementia in women

Visual hallucinations are a significant issue for many patients with Parkinson’s disease. A recent study published in the journal Brain reveals that these hallucinations are associated with a marked deficiency of cholinergic activity in specific regions of the brain, particularly the left ventral visual stream and the left superior temporal lobe. This research highlights the importance of cholinergic denervation in visual hallucinations, offering new insights into the underlying mechanisms and potential treatment options.

Visual hallucinations in Parkinson’s disease linked to cholinergic deficiency

The early warning signs of Alzheimer’s disease are plentiful and easy to detect. Sleep disruption, trouble planning simple tasks, changes in speech patterns and depression, if they appear suddenly, are some of those signs. Of course, these things don’t always signal impending Alzheimer’s. But “senior moments” are...

Memory problems: Validating Alzheimer’s first hint

A recent study has revealed significant insights into the early brain changes associated with Alzheimer’s disease, focusing on volume loss in key brain regions. The researchers found that volume loss in the basal forebrain and hippocampus is more pronounced in individuals with high levels of amyloid-beta, a protein linked to Alzheimer’s, even before cognitive symptoms become apparent. The effect of amyloid-beta concentration on the pace of brain shrinkage (volume loss) varied between brain regions. The study was published in the Neurobiology of Aging.

Scientists observe faster brain shrinkage in Alzheimer’s patients with high amyloid-beta levels

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India Currents

My article last month described dementia, its causes and prevalence, and its tell-tale signs. There is no cure at present for the debilitating and progressive disease. However, its early diagnosis enables us to develop a care plan in coordination with specialists and experts, for a better prognosis and improved quality of life for patients, caregivers, and their loved ones.

Can You Reduce The Risk Of Dementia?

Writers represent independent, third-party users who have joined our contributor program and self-verified their accounts. Writers are expected, like all users, to adhere to our Community Standards.

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Martin Vidal

One of the worst things about it is the loneliness. It was 2018, and I was 26 years old at the time. For years, doctors had been trying to get to the bottom of some breathing issues I had. I’d already been administered every allergy test available, and I underwent a sinus surgery to improve airflow through my nasal passage. But still, I was prone to getting bronchitis, having shortness of breath, and, even with daily physical exercise, I had the lung capacity of someone double my age. My primary doctor finally decided to set me up for a chest X-ray.

Opinion: The Words Every Dying Person Needs to Hear

Two recent developments in Alzheimer’s disease research offer new hope for patients living with the disease, and their families. Among those, in June, Tiziana Life Sciences received Food and Drug Administration clearance to use intranasal foralumab in its first patient with moderate Alzheimer’s disease under the FDA’s expanded access investigational new drug program.

FDA clears nasal spray for moderate Alzheimer’s disease in first patient

Researchers at the Mayo Clinic have drafted new criteria for a memory-loss disorder that bears similarities with Alzheimer's yet has a better prognosis. The corresponding article was published in Brain Communications. "This research creates a precise framework that other medical professionals can use to care for their patients. It has...

New Memory Loss Disorder that Mimics Alzheimer's Identified

According to scientists at the University of Texas Medical Branch, the newly developed nasal spray treatment could combat neurodegenerative condition like Alzheimer's disease. First author Sagar Gaikwad, from the Department of Neurology at The Mitchell Center for Neurodegenerative Diseases, told to Medical News Today, "Our study shows that the nasal tau immunotherapy importantly reverses Alzheimer's pathology in mice and a single dose is enough to achieve this."

Innovative Nasal Spray Could Help To Combat Alzheimer's Disease, Scientists Say

Months after actor and comedian Robin Williams took his own life in August 2014, autopsy results revealed he had a devastating disease: Lewy body dementia (LBD). Unlike Alzheimer's disease and even frontotemporal dementia, this brain disorder has tended to hide in the shadows. But work is underway to change that, says Dr. Stephen Gomperts, an assistant professor of neurology at Harvard Medical School and director of the Lewy Body Dementia Unit at Harvard-affiliated Massachusetts General Hospital.

What is Lewy body dementia?

EU-funded researchers are exploring new nature-based solutions to stimulate skin and bone repair. In the cities of Trento and Rovereto in northern Italy and Bangkok in Thailand, scientists are busy rearing silkworms in nurseries. They’re hoping that the caterpillars’ silk can regenerate human tissue. For such a delicate medical procedure, only thoroughbreds will do.

Silkworms and shrimp may help regenerate damaged skin and bone

Chicago, IL

Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

Parade

It's no secret that sleep is important for cognitive health—but the way you sleep matters too.

This Is the #1 Best Sleep Position for Preventing Cognitive Decline, According to Neurologists

TIME

After a specialist visited the White House, speculation about Joe Biden's health swirled. Here's how Parkinson's is actually diagnosed.

How Is Parkinson’s Disease Diagnosed?

Despite being the second-most common rheumatic autoimmune disease in the United States, Sjögren’s syndrome remains under-recognized, with patients often waiting 3 years for a proper diagnosis, according to the Sjögren’s Foundation. The disease impacts nearly 4 million Americans — nine out of 10 being women —...

World Sjögren’s Day shines light on a disease that too often goes years without diagnosis

The small pill that's well-known for treating erectile dysfunction and pulmonary hypertension might just provide the key to one of the biggest challenges of our time: Alzheimer's disease. Surprisingly, Tadalafil is now emerging in the scientific spotlight for its potential to protect and revitalize the aging brain. Recent research has shown that this unexpected connection could transform our methods of addressing Alzheimer's, providing fresh hope in the battle against cognitive decline. We're here to explore the revolutionary science surrounding Tadalafil and its unexpected role in safeguarding brain health.

The Surprising Link Between Tadalafil and the Fight Against Alzheimer's Disease

Variations in certain genes can modify the risk of developing Alzheimer’s disease (AD) and other types of dementia. Some of the best understood variants to date are in a gene called APOE. This gene plays a role in the transport of cholesterol and other fatty molecules in the brain and body. People with a variant of APOE called APOE4 have an increased risk of developing AD dementia. In contrast, people with a variant called APOE2 appear to have some protection against developing dementia.

Gene variant slows form of inherited Alzheimer’s disease

NewsBreak

Data from largest clinical trial of pre-symptomatic Alzheimer’s now widely available

Data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s (A4) study, the first and largest clinical trial of pre-symptomatic Alzheimer’s disease, is now widely available to researchers...

Data from largest clinical trial of pre-symptomatic Alzheimer’s now widely available

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