Researchers Jenny Ting, PhD, the William Kenan Distinguished Professor of Genetics and professor microbiology and immunology at the UNC School of Medicine, and Kaixin Liang, PhD, a postdoctoral researcher in the Ting lab, have identified how the COVID-19 virus causes death in the cells lining the human airways. Their findings,...

COVID-19 Causes a “Cell Death Cascade” in Airway Cells

KAUST’s NanoRanger provides quick, precise diagnosis of Mendelian genetic disorders, identifying critical genetic breakpoints efficiently. Despite rapid advances in genetic testing in recent decades, more than half of people worldwide with suspected Mendelian genetic disorders do not have an accurate molecular diagnosis. Others endure more than six years of tests before a diagnosis is given. Now, KAUST researchers and scientists across Saudi Arabia have developed NanoRanger, an accurate and rapid method for genetically diagnosing such diseases in a few hours.

NanoRanger Redefines Speed and Precision in Genetic Diagnostics

A new method that can rapidly determine whether a virus is infectious or non-infectious could revolutionise the response to future pandemics. Called FAIRY (Fluorescence Assay for vIRal IntegritY), the assay can screen viruses against virucidal antivirals in minutes, allowing for the effectiveness of antiviral measures, such as disinfectants that break the chain of infection, to be quickly determined.

New Method for Determining Virus Infectivity Could Revolutionize Future Pandemic Responses

Improving human quality of life with drug treatments is a complicated issue. Drug certification, including drug safety and reliability, entails a long series of tests and government approvals before the drug is available for anyone to use. Testing drugs is challenged by ethical and biological concerns. Testing new drugs on...

Researchers Develop 'Organ on a Chip' for Better Drug Testing

Virginia State

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Ronkonkoma, NY

Cheryl E Preston

The New York Post reveals that two men who died in a plane crash at MacArthur Airport were from Virginia. The men had been visiting friends in Long Island and were returning home when the tragedy occurred.

Life partners from Virginia have been identified as the victims of a New York plane crash

Flortaucipir PET imaging is able to identify neuropathological brain changes in retired contact sport athletes at risk of neurodegeneration, according to a study published July 22 in the Journal of Neurology. A group at the University of Toronto in Ontario, Canada, compared flortaucipir (Tauvid, Avid Pharmaceuticals) PET and MRI scans...

Tau PET identifies grey matter atrophy in retired athletes

Chronic lymphocytic leukemia (CLL) is a type of cancer affecting a type of white blood cell in the blood and bone marrow. It often progresses slowly and is diagnosed most often during routine blood testing. Understanding the stages of CLL—from stage 0 to 4—can help you navigate a CLL diagnosis....

Stages of Chronic Lymphocytic Leukemia (CLL)

Interesting Engineering

Inbrain's graphene chip is a promising new technology with the potential to improve brain surgery and neurological treatments.

Graphene-based brain chip offers 200x more power for Parkinson’s patients

Kentucky State

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Northern Kentucky Tribune

Kentucky’s medical cannabis program has taken significant steps toward ensuring those with qualifying conditions have access to medical cannabis as soon as possible, said Gov. Andy Beshear this week.

State to open licensing applications for medical cannabis businesses beginning July 1

Implementing and maintaining a competitive advantage is an ever-present challenge in a global economy. For analytical laboratories, this can be accomplished by achieving improvements in both performance and usability through the use of modern High Performance Liquid Chromatography (HPLC) instrumentation. Assessment of a new HPLC instrumentation platform to understand the various system configurations is important to achieving successful results. Another key aspect to reduce the variability from one laboratory to another is to understand specific method conditions and other variables that can impact chromatographic reproducibility. To address these challenges, a solid understanding of variables that can impact method performance should be assessed.

Global Cross Lab Method Transfer of a USP Impurities Method on the Alliance™ iS HPLC System

The US Sun

A SINGLE-dose nasal spray treatment could 'wash away' build ups of toxic proteins associated with Alzheimer’s disease from brain cells and improve memory, scientists say. The study - performed on mice - paves the way for new treatments against Alzheimer's and dementia, researchers at the University of Texas Medical Branch said.

Single-dose nasal spray ‘washes the brain’ of toxic Alzheimer’s proteins – paving the way for breakthrough treatment

Chicago, IL

Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

In a focused discussion, Anne Chiang, MD, PhD, explores the sequencing of later-line therapies for limited-stage small cell lung cancer (LS-SCLC), emphasizing key factors to consider when making treatment decisions for patients who have progressed on initial therapy. Video content above is prompted by the following questions:. After frontline therapy...

Navigating Later-Line Therapy Sequencing in LS-SCLC Progression

Gov. Andy Beshear sent a letter to Anne Milgram, administrator for the U.S. Drug Enforcement Administration (DEA) on Wednesday, expressing his support of the U.S. Department of Health and Human Services’ recommendation that the DEA ease restrictions on marijuana.

Gov. Andy Beshear pens letter to DEA in support of easing federal restrictions on marijuana

USC scientists have discovered a way to turn the body’s B cells into tiny surveillance machines and antibody factories that can pump out specially designed antibodies to destroy cancer cells or HIV, two of medicine’s most formidable foes. The research, published Monday in Nature Biomedical Engineering, describes a...

Researchers Turn B Cells Into Antibody Factories To Combat HIV and Cancer

Uveal melanoma is a rare cancer type with an incidence of 7.6 per million adults in Australia and represents around 5% of all melanomas. Patients presenting with uveal melanoma have a 50% chance of the disease metastasising or spreading from the eye, commonly to the liver, even after successful treatment of the tumours within the eye.

Study Takes a Closer Look at Eye Cancer’s High Rate of Metastasis

MedwireNews: Researchers have used a machine learning approach to create a panel of eight blood biomarkers that can identify people at risk for developing Parkinson’s disease (PD) up to 7 years before the first signs or symptoms. “Our identified panel of blood biomarkers significantly advances NSD [neuronal synuclein disease]...

Blood test predicts Parkinson’s disease up to 7 years before symptom onset

The majority of rare diseases have a genetic cause. The underlying genetic alteration can be found more and more easily, for example by means of exome sequencing (ES), leading to a molecular genetic diagnosis. ES is an examination of all sections of our genetic material (DNA) that code for proteins. As part of a Germany-wide multicenter study, ES data was collected from 1,577 patients and systematically evaluated. This made it possible to diagnose a total of 499 patients, with 34 patients showing new, previously unknown genetic diseases. The study thus makes a significant contribution to the initial description of new diseases. In addition, software based on the use of artificial intelligence (AI) was used for the first time on a broad scale to support clinical diagnosis. The "GestaltMatcher" AI system can assist in the assessment of facial features with regard to the classification of congenital genetic syndromes. The results of the study, in which 16 universities and university hospitals were involved, including the University of Bonn, have now been published in the renowned journal "Nature Genetics".

Study of 1,577 Patients Identifies 34 New Genetic Diseases

Scientists have discovered that some cancer cells pretend to be ‘super fit’ to fool normal healthy cells into giving them their nutrients, allowing them to expand and spread around the body. A team from The Institute of Cancer Research, London, found that ‘cheating’ cancer cells develop the ability...

“Cheating” Cancer Cells Outsmart Normal Cells To Invade the Body

Cancer cells can hijack cell cycles to exponentially increase their numbers, a process called proliferation. Cancer drugs can stop the growth of cancer cells by jumpstarting a complex chain of genetic and cellular events. But often, this story is more complex, involving treatments that don’t work as well as had been hoped.

How Do Cancer Cells Divide Despite Treatment?

NewsBreak

Leveraging Proteomics for Clinical Biomarker Discovery

Over the last 40 years, molecular blood-based biomarkers have become increasingly important in the diagnosis, treatment and management of disease. In particular, the last decade has...

Leveraging Proteomics for Clinical Biomarker Discovery

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