The US Sun

A SINGLE-dose nasal spray treatment could 'wash away' build ups of toxic proteins associated with Alzheimer’s disease from brain cells and improve memory, scientists say. The study - performed on mice - paves the way for new treatments against Alzheimer's and dementia, researchers at the University of Texas Medical Branch said.

Single-dose nasal spray ‘washes the brain’ of toxic Alzheimer’s proteins – paving the way for breakthrough treatment

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Parkinson’s disease is a progressive neurodegenerative disorder that affects millions of people worldwide. Characterized by tremors, stiffness, and difficulty with balance and coordination, the disease is primarily caused by the loss of dopamine-prod...

3 Supplements A Neuroscientist Swears By To Prevent Parkinson’s Disease: ‘Gives Your Brain The Raw Materials To Repair Itself’

Some natural remedies, such as music therapy or supplements, may complement medical treatments for Parkinson’s disease and improve overall health. Parkinson’s disease (PD) is a progressive neurological disorder that affects your body’s movement, muscle control, and balance. It can also affect your cognitive function, senses, and mental health. While there’s no cure, medications, surgeries, and lifestyle changes can relieve symptoms and improve your quality of life.

Can You Treat Parkinson’s Disease Naturally?

Visual hallucinations are a significant issue for many patients with Parkinson’s disease. A recent study published in the journal Brain reveals that these hallucinations are associated with a marked deficiency of cholinergic activity in specific regions of the brain, particularly the left ventral visual stream and the left superior temporal lobe. This research highlights the importance of cholinergic denervation in visual hallucinations, offering new insights into the underlying mechanisms and potential treatment options.

Visual hallucinations in Parkinson’s disease linked to cholinergic deficiency

A study reveals that brain inflammation leads to the release of a protein that impairs muscle function, suggesting potential treatments for related muscle fatigue in diseases like Alzheimer’s and long COVID. Infections and neurodegenerative diseases are known to cause brain inflammation. However, patients with brain inflammation often develop muscle...

Hidden Connection Discovered: New Research Links Brain Inflammation to Muscle Fatigue

San Diego, CA

An unusually large brain may be the first sign of autism — and visible as early as the first trimester, according to a recent study conducted by UCSD. Some children with profound autism face lifelong challenges with social, language, and cognitive skills, including the inability to speak. In contrast, others exhibit milder symptoms that may improve over time.

Scientists Have Uncovered Autism’s Earliest Biological Signs

Past studies have suggested that taking cholesterol-lowering statin drugs may lower individuals’ risk of developing liver cancer. In a new study of non-statin cholesterol-lowering medications, one type was linked to lower risks of liver cancer. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

Non-Statin Cholesterol-Lowering Drug Linked to Lower Liver Cancer Risk

South Carolina State

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Explore Beaufort SC

The mantis shrimp is one tough customer. Beautiful and deadly are two words you don’t typically use to describe shrimp, but the mantis shrimp is definitely in a class of its own; earning a reputation as the ‘savage boxer of the sea’ and one of the most fearsome creatures in the ocean. And, they're right at home here in South Carolina.

Savage Boxer of the Sea: The Deadly Beauty of Mantis Shrimp

The company acquired the program, along with Spark Therapeutics’ pipeline, in December 2019. Roche has discontinued development of its investigational gene therapy SPK-3006, which was being evaluated in the phase 1/2 RESOLUTE trial (NCT04093349) in participants with late-onset Pompe disease.1. Roche adopted the program into its pipeline along with...

Roche Drops Pompe Gene Therapy Program

Total Apex Sports & Entertainment

Do your loved ones consult you regularly when they face a crisis? Intelligence is a branch of psychology that lacks a standard definition. Some scientists claim that it is a single ability and others state it comprises aptitudes and skills. Intelligent zodiac signs learn from their experiences and easily recognize and solve problems.

5 Most Intelligent Zodiac Signs

The study is expected to evaluate the safety of Iomab-ACT in sickle cell disease patients who are undergoing allogeneic bone marrow transplants. The FDA has cleared Actnium Pharmaceuticals’ Investigational New Drug (IND) application to study Iomab-ACT, a targeted radiotherapy conditioning agent, developed in a partnership with Columbia University for the treatment of patients with sickle cell disease (SCD) who are undergoing allogeneic bone marrow transplants (BMT). The study, which will be led by Markus Mapara, MD, PhD, professor of medicine, Colombia University Irving Medical Center, director, Bone Marrow Transplantation and Cell Therapy Program, Vagelos College of Physicians and Surgeons, will evaluate the safety of Iomab-ACT in this patient population.1.

FDA Clears Investigational New Drug Application for Actinium Pharmaceuticals’ Iomab-ACT in Patients with Sickle Cell Disease

Hair follicle infections are often difficult to treat because bacteria settle in the gap between hair and skin, where it is difficult for active substances to reach them. In order to investigate this scenario more closely in the laboratory, researchers from the Department of Drug Delivery Across Biological Barriers at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have now developed a model with human hair follicles embedded in a matrix produced using 3D printing. In the future, this model can be used to test the effectiveness of new drug candidates against corresponding pathogens directly on human follicles. The team has published their results in the journal ACS Biomaterials Science & Engineering.

3D Printed Hair Follicle Model Enhances Early Drug Testing

Multiple sclerosis (MS) is a disease that damages the nerves of the central nervous system. This damage disrupts nerve impulses and can lead to ataxia — a condition that affects coordination, balance, and speech. This article outlines the symptoms of ataxia. It also considers the prevalence of this condition...

What to know about ataxia in multiple sclerosis

Bone cancer is a rare type of cancer, which can go undetected for some time before being diagnosed. Although benign (non-cancerous) bone tumors are more common than malignant (cancerous) bone tumors, malignant bone cancer can be an aggressive cancer, and some types grow quickly. Quick progression makes early detection and treatment all the more important.

Bone Cancer Without Knowing: How Long Can It Go Undiagnosed?

Chicago, IL

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Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

Scientists analysed ancient DNA extracted from an 8,000-year-old sheep bone and detected the Brucella melitensis pathogen. Brucellosis affects millions of people every year and causes significant harm to the welfare of livestock. Passed on by the consumption of unpasteurised milk and close contact with infected animals, brucellosis can cause waves...

Neolithic Roots of Brucellosis Infection Uncovered

Positive trial results show the specialized cell product achieved an overall slowing of disease worsening compared to placebo. Lomecel-B, a living cell product for the treatment of Alzheimer’s Disease, has met key primary and secondary endpoints in the Phase IIa CLEAR MIND clinical trial (NCT05233774). Among emerging, positive results from the study, Longeveron’s potential therapy showed an overall slowing of disease worsening compared to placebo.1.

Lomecel-B Meets Key Objectives in Phase IIa Alzheimer’s Study

Medical News Today

Researchers have found unique molecular changes in the blood-brain barrier of people with Alzheimer’s disease, markers of which can be detected in the blood.

Study identifies Alzheimer's biomarkers linked to blood vessel changes in the brain

Months after actor and comedian Robin Williams took his own life in August 2014, autopsy results revealed he had a devastating disease: Lewy body dementia (LBD). Unlike Alzheimer's disease and even frontotemporal dementia, this brain disorder has tended to hide in the shadows. But work is underway to change that, says Dr. Stephen Gomperts, an assistant professor of neurology at Harvard Medical School and director of the Lewy Body Dementia Unit at Harvard-affiliated Massachusetts General Hospital.

What is Lewy body dementia?

Boston, MA

Dianna Carney

The Scituate Animal Shelter of Massachusetts recently introduced two special poodles, Delia and Elle, who were found as strays in Boston just two days apart. Despite their initial separation, these poodles were reunited at the animal shelter, and it was immediately clear that they knew each other well. The shelter shared their heartwarming story, stating:

Meet Delia & Elle: The Stray Dogs Who Found Each Other Against All Odds

NewsBreak

Embryonic Abnormalities in SMA May Lead to New Therapies

Spinal muscular atrophy (SMA) is a severe neurological disease for which there is presently no cure, although current therapies can alleviate symptoms. In the search for...

Embryonic Abnormalities in SMA May Lead to New Therapies

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