Shield, the first FDA-approved blood test for CRC screening, may offer convenient screening access for those who are at average risk for the disease. The FDA has approved ShieldTM, a noninvasive, blood-based test designed to screen for colorectal cancer (CRC) in individuals 45 years and older who are at average risk of developing the disease, according to a press release from the developer, Guardant Health, Inc.1.

FDA Approves Blood Test for Colorectal Cancer Screening

Camber Spine earned FDA 510(k) approval for its Spira-A integrated fixation system. The device is designed for anterior lumbar interbody fusion and allows packing with bone graft material, according to a July 23 news release. Spira-A is indicated for use at one or more levels in the lumbar spine for adults with degenerative disc disease, disc herniation spondylolisthesis, deformity, spinal stenosis and failed spinal fusion.

Camber Spine earns FDA nod for SPIRA-A device

Today, a brief rundown of news from Vertex Pharmaceuticals and Merck & Co. as well as updates from Fibrogen, Intellia Therapeutics and Biogen that you may have missed. The Food and Drug Administration has agreed to a speedy review of Vertex Pharmaceuticals’ closely watched pain tablet. An approval decision should come by Jan. 30. The tablet works differently than available pain medications, instead targeting a kind of microscopic cell tunnel that controls nerve cell communication. Wall Street analysts see Vertex’s drug as a valuable, non-opioid option for pain management, and expect annual sales will eventually crest $5 billion.— Jacob Bell.

Vertex’s pain drug gets speedy FDA review; Keytruda hits a sales milestone

A healthy 38-year-old who began struggling to finish a half-marathon and experienced night sweats, body aches, and COVID-like symptoms learned he was facing stage 4 non-Hodgkin lymphoma. Despite the shocking diagnosis, he plans to remain positive while he fights the cancer. Lymphoma is a blood cancer, specifically of the immune...

Fit, Healthy Man, 38, With Swollen Knee Felt Covid-Like Symptoms for a Month Before Learning He Had Stage 4 Non-Hodgkin Lymphoma

Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the blood and bone marrow. It can progress slowly and may not cause many symptoms. Although it is treatable, it’s not considered to be curable. In the early stages, CLL often doesn't require treatment immediately, as studies have...

Chronic Lymphocytic Leukemia (CLL): When to Treat Cancer or Hold Off

Doctors monitor lymphocyte and other blood cell levels to predict how your lymphoma will progress. Low lymphocyte counts may suggest that cancer has spread to your bone marrow, or it can be a side effect of treatments. Lymphoma is a group of cancers that develop in your lymphocytes. These white...

Understanding Lymphocyte Levels in Lymphoma: Uses and Significance

Combining IMNN-001 with chemotherapy also elicited a progression-free survival improvement compared with chemotherapy alone in the OVATION 2 trial. Administering the DNA-mediated immunotherapy IMNN-001 in combination with neoadjuvant and adjuvant chemotherapy (NACT) improved overall survival (OS) compared with NACT alone among patients with advanced ovarian cancer, according to data from the phase 2 OVATION 2 study (NCT03393884).1.

IMNN-001/Chemo Improves Survival in Advanced Ovarian Cancer

Posted on Jul 26, 2024, 2 p.m. A team of researchers reveals the cellular pathology of “dry” age-related macular degeneration (AMD); discovering the potential source of dysfunction in the process whereby cells in the retina remove waste. What. The team from NIH and Johns Hopkins University, Baltimore, reported...

Potential Therapeutic Target For Age-Related Macular Degeneration

A combination mRNA cancer vaccine from BioNTech and Regeneron may be one step closer to actualization based on initial Phase 2 results unveiled Tuesday. The mRNA-based vaccine, BNT111, in combination with Regeneron’s cemiplimab met its primary efficacy outcome measure and showed significant improvement in objective response rate (ORR). The...

BioNTech, Regeneron tout mRNA cancer vaccine’s Phase 2 trial results

Researchers say a non-chemotherapy treatment is causing more cancer patients to experience full remission. A recent National Cancer Institute study shows that a new targeted therapy can help prolong the time cancer patients are in remission. Called the ViPOR regimen, the non-chemotherapy treatment shrinks tumors of those who suffer from B-cell lymphoma.

NCI Precision Medicine Study Hones in on Cancer Remission

Chicago, IL

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Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

The American Liver Foundation (ALF) has announced a new program that will educate non-liver experts on treatment and prevention practices for metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as non-alcoholic fatty liver disease, or NAFLD), according to an ALF news release. Beginning in August, Project Echo will offer monthly...

American Liver Foundation Announces Fatty Liver Disease Education Program

The investigational mRNA therapy BNT111 plus cemiplimab showed better overall response rates compared with historical controls in patients with stage III/IV melanoma refractory to anti-PD-(L)1 therapy. A phase 2 trial (NCT04526899) investigating an investigational mRNA cancer immunotherapy, BNT111, plus cemiplimab (Libtayo) in patients with unresectable stage III or IV melanoma...

BNT111/Cemiplimab Shows Significant ORR Improvement in Stage III/IV Melanoma

Case: A 60-Year-Old Woman with Later Relapsed/Refractory Multiple Myeloma. A 60-year-old woman who was previously diagnosed 3 years ago with R-ISS stage 2/R2-ISS stage III IgG-lambda multiple myeloma presents to his oncologist after two prior treatment regimens. Ca 12.5 mg/dL; SCr 2.5 mg/dL. Hgb 8.2 g/dL; LDH 290 U/L; Albumin...

Community-Based Care: Key Strategies for Effective R/R MM Management

Colorado State

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David Heitz

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

The U.S. Food and Drug Administration (FDA) gave the greenlight for Iomab-ACT, a potentially less toxic conditioning regimen, to be tested in people with sickle cell disease (SCD) undergoing a stem cell transplant. The study will be conducted in collaboration between Actinium Pharmaceuticals, which is developing Iomab-ACT, and Columbia University...

FDA clears testing of potentially less toxic conditioning regimen for SCD

The following is a summary of “Influence of cryoablation versus operation on circulating lymphocyte subsets in patients with early-stage renal cell carcinoma,” published in the July 2024 issue of Oncology by Waidhauser et al. The immune response is pivotal in local tumor control, particularly in renal cell carcinoma...

Impact of Cryoablation vs. Surgery on Circulating Lymphocyte Subsets in Early-Stage RCC

Denver, CO

A dangerous drug that is being mixed into fentanyl is causing those who inject it to develop a rash of sores that resembles a case of flesh-eating bacteria. People experiencing homelessness around Denver can sometimes be seen with these bloody, weeping wounds. I recently mentioned this phenomenon to a fentanyl user who told me about the xylazine connection.

Denver homeless people suffer sores as xylazine enters fentanyl supply

“Patients did great” with a four-drug regimen for multiple myeloma, an expert told CURE®. Patients with newly diagnosed multiple myeloma treated with the four-drug combination of Sarclisa (isatuximab), Kyprolis (carfilzomib), Revlimid (lenalidomide) and dexamethasone (a regimen known as Isa-KRd) experienced what researchers described as “deep and durable” responses, according to study findings.

Isa-KRd Elicits Responses in Some With Newly Diagnosed Multiple Myeloma

Arizona State

Arizona Luminaria

Kari Lake appears to have won the Republican primary for U.S. Senate with about two thirds of votes counted. She will face Democrat Ruben Gallego in the general election. In the Republican primary for U.S. House of Representatives District 6 — a swing district with a history of close elections that includes parts of Pima, Pinal, Cochise, Graham and Greenlee counties — incumbent Juan Ciscomani defeated challenger Kathleen Winn.

Live Arizona election results: Kari Lake and Juan Ciscomani win primaries

NewsBreak

FDA Clears COM503 IND in Solid Tumors, Phase 1 Trial Anticipated

A phase 1 trial of COM503 in metastatic or advanced solid tumors is expected to begin in Q4 2024. The FDA has cleared the investigational new...

FDA Clears COM503 IND in Solid Tumors, Phase 1 Trial Anticipated

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