The Food and Drug Administration has given the go-ahead for a late-stage clinical trial of an injectable stem cell product that could give new hope to millions of patients suffering from lower back pain caused by degenerative disc disease (DDD). Up to 400 patients with mild to moderate DDD are expected to enroll in the Phase 3 study later this year.

FDA Approves Stem Cell Study for Degenerative Disc Disease

Oncology medications made up 24.14% of pharmacy program participants' drug spend from April 2023 to March 2024, according to Vizient's "Summer 2024 Pharmacy Market Outlook" report. The report, released July 30, analyzed pharmacy program participants' purchase data from April 2023 to March 2024 and provides an estimate of pharmaceutical price...

Top medication spend for oncology drugs

A second dendritic cell vaccine has received fast track designation from the Food and Drug Administration. The Food and Drug Administration (FDA) has granted a fast track designation to a dendritic cell vaccine for the treatment of patients with pancreatic ductal adenocarcinoma. Immuno-oncology company Diakonos Oncology Corporation announced the designation...

FDA Fast Tracks Pancreatic Cancer Vaccine

The FDA has approved dostarlimab plus carboplatin and paclitaxel, followed by single-agent dostarlimab, for primary advanced or recurrent endometrial cancer. The FDA has approved dostarlimab-gxly (Jemperli) in combination with carboplatin and paclitaxel, followed by single-agent dostarlimab, for the treatment of adult patients with primary advanced or recurrent endometrial cancer.1,2. Previously...

FDA Approves Expanded Indication for Dostarlimab Plus Chemo in Primary Advanced or Recurrent Endometrial Cancer

Cigna is planning to vigorously defend its pharmacy benefit manager from scrutiny. On an Aug. 1 call with investors, Cigna Group CEO David Cordani said the company will be more aggressive in communicating the value of its PBM to lawmakers, customers and the public. "We challenge ourselves to be much...

Cigna prepares 'aggressive' defense of PBMs

MadameNoire

Pulmonary edema is a critical condition where fluid accumulates in the lungs.

Recognizing Pulmonary Edema: Key Warning Signs To Watch For

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Anika Jindal

A shower is an essential grooming ritual in most people’s routines. Yet, one could be unknowingly doing things that are unusual blunders. Let’s look at 14 weird, unsanitary, unhealthy, or dangerous things one shouldn’t do in a shower.

14 Things You Shouldn’t Do in Shower

You’ve probably already heard of the ‘gut-brain axis’. It’s the biochemical signaling pathway between the gastrointestinal tract and your central nervous system, which has already been associated with bowel disease and dementia, as well as GERD and chronic headaches. It’s also why a good night’s sleep...

7 GI conditions linked with brain aneurysm

A rare, but fatal genetic disease that accelerates aging in children, progeria, could soon have a cure, The New York Times reported July 24. The disease affects only 1 in every 4 million to 8 million live births, and causes early signs of aging from balding and wrinkles, to arthritis, cataracts, tough skin, and stiff joints. The prevalence of the disease overall is about 1 in 18 million to 20 million worldwide, according to the Progeria Research Foundation, with about 400 children living with the condition presently — 18 of whom are in the U.S.

Physicians closing in on cure to 'rapid aging' disease

Doctors monitor lymphocyte and other blood cell levels to predict how your lymphoma will progress. Low lymphocyte counts may suggest that cancer has spread to your bone marrow, or it can be a side effect of treatments. Lymphoma is a group of cancers that develop in your lymphocytes. These white...

Understanding Lymphocyte Levels in Lymphoma: Uses and Significance

New York City, NY

Cheryl E Preston

Yesterday was the third time this year that an ad stating Chelsea Clinton lives in a beautiful Virginia home popped up on my laptop. My computer did not warn me this was a dangerous site, so this time, I clicked on the link.

Chelsea Clinton is rumored to be living in Virginia but probably still in NYC

A strain of bacteria that causes severe and sometimes drug-resistant infections has been detected in all six World Health Organization regions, the group reported July 31. A 2022 study on Hypervirulent Klebsiella pneumoniae recorded "the highest percentage of antibiotic resistance in hvKp group compared to previous studies indicating a dramatic increase in multidrug resistant hvKp strains," the authors wrote then.

WHO warns of moderate-risk level for drug-resistant K. pneumoniae

Chicago, IL

Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

Irish Star

The newly discovered gene is said to play a crucial role in the proper functioning of many organs and could be the answer to controlling one of the deadliest cancers known

Scientists may have found key gene to stop one of deadliest cancers

North Carolina State

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Town Talks

In North Carolina, the divorce process can be challenging, particularly due to the mandatory one-year separation requirement. This law mandates that couples must live separately for at least a year before filing for divorce, a rule that can be frustrating for many.

You might be granted a divorce in North Carolina if your spouse is ‘incurably insane.’ Here’s how

The American Heart Association's new cardiovascular disease event prediction equations could leave 14.3 million patients ineligible for statin therapy, according to a study published July 29 in JAMA. The AHA and the American College of Cardiology have recommended using pooled cohort equations to predict a patient's 10-year risk of cardiovascular...

New AHA guidelines could make millions ineligible for statins: Study

In the last 6 months prior to PDAC diagnosis, visceral and subcutaneous adipose tissue decreased by 12.9% and 14.7%, respectively. LDL, total cholesterol and triglycerides also decreased before diagnosis. In the 36 months prior to diagnosis of pancreatic ductal adenocarcinoma, researchers observed “predominant changes” in patients’ body composition and biochemical...

Body fat, metabolic changes before pancreatic cancer diagnosis may aid in early detection

Denver, CO

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David Heitz

A dangerous drug that is being mixed into fentanyl is causing those who inject it to develop a rash of sores that resembles a case of flesh-eating bacteria. People experiencing homelessness around Denver can sometimes be seen with these bloody, weeping wounds. I recently mentioned this phenomenon to a fentanyl user who told me about the xylazine connection.

Denver homeless people suffer sores as xylazine enters fentanyl supply

As North Carolina continues to attract new residents, understanding the rights and obligations of both tenants and landlords becomes increasingly important. Here’s what you need to know about landlord entry and tenant rights in the state.

Can landlords enter at any time, or is it trespassing? Here are the rules in North Carolina

Tennessee State

Cancer treatment deserts are growing as more rural hospitals close and cut services, CBS News reported Aug. 1. Between 2014 and 2022, 382 rural hospitals halted chemotherapy services, Charis, a health analytics and consulting firm, found in a report published this spring. Texas had the highest percentage of rural hospitals that eliminated chemotherapy services at 47%. Next came Alabama (46%), Mississippi (45%), Tennessee (44%), and Florida (39%).

Cancer care deserts are spreading

NewsBreak

2 cancer drugs receive FDA designations

The FDA has granted designations for cancer drug therapies addressing pancreatic cancer and melanoma. Verastem Oncology received an orphan drug designation from the FDA for its...

2 cancer drugs receive FDA designations

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