Columbus, OH

A second dendritic cell vaccine has received fast track designation from the Food and Drug Administration. The Food and Drug Administration (FDA) has granted a fast track designation to a dendritic cell vaccine for the treatment of patients with pancreatic ductal adenocarcinoma. Immuno-oncology company Diakonos Oncology Corporation announced the designation...

FDA Fast Tracks Pancreatic Cancer Vaccine

The FDA granted accelerated approval to afamitresgene autoleucel for certain adults with unresectable or metastatic synovial sarcoma. The indication applies to patients who received prior chemotherapy, are HLA-A*02:01P, HLA-A*02:02P, HLA-A*02:03P or HLA-A*02:06P positive and whose tumor expresses the MAGE-A4 antigen. Afamitresgene autoleucel (Tecelra, Adaptimmune LLC) is a melanoma-associated antigen A4...

FDA approves T-cell immunotherapy for advanced synovial sarcoma

The Hill

A new blood test to screen for colon cancer was approved Monday by the Food and Drug Administration (FDA), aimed at finding cancer when it’s still in the early stage and treatable.  The blood test, known as Shield and manufactured by Guardant Health, has been on the market since 2022 but was not widely covered by…

FDA approves new blood test for colorectal cancer screening

A drug that was developed to treat pancreatic cancer has now been shown to increase symptom-free survival in preclinical medulloblastoma models – all without showing signs of toxicity. Medulloblastoma is the most common malignant brain tumor in children. Survival rates vary according to which one of the four subtypes...

Drug developed for pancreatic cancer shows promise against most aggressive form of medulloblastoma

Health

Medically reviewed by Gagandeep Brar, MDMedically reviewed by Gagandeep Brar, MDThe red cell distribution width (RDW) blood test measures the differences in the volume and size of your red blood cells. Red blood cells help carry oxygen from the lungs to other parts of your body. Changes in the size of your red blood cells often represent a sign of an underlying medical condition, such as anemia (a reduced number of red blood cells or hemoglobin).Your healthcare provider may recommend an RDW test if they suspect you have an underlying condition. A high RDW means there is significant variation in...

What Do Your Red Cell Distribution Width (RDW) Blood Test Results Mean?

Diverticulitis and colon cancer share some similar symptoms, risk factors, and diagnostic tests. Research suggests there may be a link between the two conditions, and having diverticulitis may increase the risk of colon cancer. Diverticulitis and colon cancer both involve the colon, which forms part of the large intestine. Colon...

Is there a connection between diverticulitis and colon cancer?

Results suggest cholesterol absorption inhibitors are linked to a lower risk of liver cancer, but no association was observed for other nonstatins like fibrates, omega-3 fatty acids, and niacin. Findings from a recent study are providing clinicians with an overview of the association between nonstatin cholesterol-lowering medications and the risk...

Cholesterol Absorption Inhibitors Linked to Reduced Liver Cancer Risk

Chicago, IL

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Foodie in Chicago

Shortly before 3 AM, people in the Chicago area may have felt their houses shake as a 3.4-magnitude earthquake occurred about 60 miles west of the city. (CHICAGO) The United States Geological Survey (USGS) reported a 3.4-magnitude earthquake around Somonauk, IL. Somonauk is in DeKalb and LaSalle Counties, 64 miles west of Chicago.

Did You Feel the Earthquake?

Doctors typically divide small cell lung cancer (SCLC) into limited or extensive stages, depending on whether the cancer is in one lung, both lungs, or has spread to distant areas. Staging for small cell lung cancer (SCLC) can help identify how advanced the cancer is and its best treatment. In...

How does small cell lung cancer staging work?

MedwireNews: Findings from the Cancer of the Pancreas Screening program in the USA support the use of annual endoscopic ultrasound (EUS) or magnetic resonance imaging (MRI) for patients with a familial or genetic predisposition for pancreatic ductal adenocarcinoma (PDAC). “Surveillance of high-risk individuals for PDAC using EUS and MRI within...

Annual screening supported for people at high-risk of pancreatic ductal adenocarcinoma

SurvivorNet

A healthy 38-year-old who began struggling to finish a half-marathon and experienced night sweats, body aches, and COVID-like symptoms learned he was facing stage 4 non-Hodgkin lymphoma. Despite the shocking diagnosis, he plans to remain positive while he fights the cancer.

Fit, Healthy Man, 38, With Swollen Knee Felt Covid-Like Symptoms for a Month Before Learning He Had Stage 4 Non-Hodgkin Lymphoma

Everyday Health

Hypoglycemia symptoms include having anxiety, emotional instability, dizziness, and lightheadedness. Here's a list with more signs to watch for.

10 Warning Signs of Low Blood Sugar

Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the blood and bone marrow. It can progress slowly and may not cause many symptoms. Although it is treatable, it’s not considered to be curable. In the early stages, CLL often doesn't require treatment immediately, as studies have...

Chronic Lymphocytic Leukemia (CLL): When to Treat Cancer or Hold Off

Q: What Is the Role of Metal Biliary Stents in Patients With Unresectable Pancreatic Cancer and Jaundice?. A: More than 33,000 people are diagnosed with pancreatic cancer in the United States every year. Only 15% to 20% of the patients who are diagnosed with pancreatic cancer will have resectable disease at the time of initial presentation. The median survival of these patients varies from 3 to 6 months (for patients with remote metastases) to 7 to 12 months (those with locally advanced, unresectable pancreatic cancer). Patients with the cancer located in the pancreatic head usually present with obstructive jaundice and pruritis, and palliation of these symptoms and its consequences significantly improve patients’ quality of life.

Biliary Stents Pose Relative Risks, Benefits to Patients

Researchers say a non-chemotherapy treatment is causing more cancer patients to experience full remission. A recent National Cancer Institute study shows that a new targeted therapy can help prolong the time cancer patients are in remission. Called the ViPOR regimen, the non-chemotherapy treatment shrinks tumors of those who suffer from B-cell lymphoma.

NCI Precision Medicine Study Hones in on Cancer Remission

Patients with advanced chronic kidney disease may benefit from use of angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers. Use of these drugs was not linked with reduced mortality risk. Patients with advanced chronic kidney disease may benefit from angiotensin-converting enzyme inhibitor and angiotensin-receptor blocker use, but the antihypertensive agents may not...

Angiotensin-converting enzyme inhibitors, receptor blockers may benefit patients with CKD

Study shows patients 80 years and older with atrial fibrillation treated with a lower dose of edoxaban experienced fewer major gastrointestinal bleeding events for each additional ischemic stroke. Patients aged 80 years and above with atrial fibrillation (AF) may gain a benefit from treatment with lower-dose anticoagulants regardless of existing...

Phase III Trial Shows Older Patients with Atrial Fibrillation May Benefit From Lower-Dose Anticoagulants

The following is a summary of “Role of thymectomy in surgical treatment of renal hyperparathyroidism,” published in the July 2024 issue of Surgery by Guo et al. The role of routine thymectomy in the surgical management of secondary or tertiary hyperparathyroidism (SHPT, THPT) remains controversial. This study aimed to assess the impact of thymectomy on recurrence rates and postoperative complications in patients undergoing subtotal parathyroidectomy for renal hyperparathyroidism. A retrospective review was conducted of patients treated at a tertiary endocrine surgery center from 2010 to 2022. Histopathological reports were examined to identify the presence of parathyroid tissue in resected specimens. Using multivariate logistic regression, the researchers compared baseline characteristics, recurrence rates, and complications between patients who underwent subtotal parathyroidectomy with and without concurrent thymectomy. Out of 107 patients who received subtotal parathyroidectomy, 29 (27.1%) also underwent thymectomy.

Understanding Surgical Treatment of Renal Hyperparathyroidism and the Role of Thymectomy

Tecelra is the first cell therapy to be approved for a solid cancer in the United States, and marks the end of a decade-long drought of new drugs for this patient population. The Food and Drug Administration (FDA) granted an accelerated approval to Tecelra (afamitresgene autoleucel) to treat adults with unresectable (cannot be removed via surgery) or metastatic synovial sarcoma that has previously been treated with chemotherapy. The approval is specifically for patients with HLA-A*02:01P, -A*02:02P, -A*02:03P, or -A*02:06P-positive disease that expresses the MAGE-A4 antigen, as determined by an FDA-approved test.

FDA Approves Tecelra to Treat Synovial Sarcoma

Doctors monitor lymphocyte and other blood cell levels to predict how your lymphoma will progress. Low lymphocyte counts may suggest that cancer has spread to your bone marrow, or it can be a side effect of treatments. Lymphoma is a group of cancers that develop in your lymphocytes. These white...

Understanding Lymphocyte Levels in Lymphoma: Uses and Significance

NewsBreak

The Targeted Pulse: FDA’s ODAC Mandates New Phase Assessment Protocols in NSCLC, Dendritic Cell Vaccine Gains Ground in Pancreatic Cancer, and More

The FDA’s ODAC mandates phase assessments for NSCLC trials, dendritic cell immunotherapy shows improved survival in pancreatic cancer, and a new blood test for colorectal cancer...

The Targeted Pulse: FDA’s ODAC Mandates New Phase Assessment Protocols in NSCLC, Dendritic Cell Vaccine Gains Ground in Pancreatic Cancer, and More

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