LiveScience

Scientists are developing an engineered parasite to get drugs into the brain.

Genetically engineered 'mind control' parasite could deliver drugs to the brain

North Carolina State University researchers have made groundbreaking discoveries by examining the genetic material of historic potato leaves. Their study highlights the dynamic evolutionary battle between potato plants and the pathogen responsible for the Irish potato famine. By employing innovative DNA sequencing techniques, they have uncovered how certain pathogen strains could overcome resistance genes before these were even used in breeding, suggesting new directions for future agricultural strategies.

Ancient DNA Reveals Secrets of Potato Pathogen Wars

A research group led by Prof. Wang Hui from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences introduced an axial O atom-modulated Fe-N4 nanozymes for realizing efficient H2O2 Russell reaction to singlet oxygen (1O2) at hypoxic environment without external stimulus. The study was published in Advanced...

Novel single-atom nanozymes show promise for hypoxia-tolerant singlet oxygen-battery

Genes from regenerative organisms rejuvenate intestinal stem cells in fruit flies. In a groundbreaking experiment, Japanese researchers transferred regenerative genes to fruit flies, leading to improved intestinal health and enhanced stem cell activity. This discovery opens new possibilities for anti-aging strategies in higher organisms, including humans, through targeted gene therapy.

Anti-Aging Treatment Breakthrough: Japanese Scientists’ Regenerative Gene Transfer Success

A team at Northwestern University has come up with the term “dancing molecules” to describe an invention of synthetic nanofibers which they say have the potential to quicken the regeneration of cartilage damage beyond what our body is capable of. The moniker was coined back in November 2021,...

Nanofiber Molecules Help Repair Cartilage Damage in Joints by ‘Regenerating Tissue’

New York City, NY

TechSpot

Serving tech enthusiasts for over 25 years. What just happened? While there are many therapies available to treat diabetes, none have proven to completely reverse this disease. That may change as research from the Mount Sinai Health System and the City of Hope continues to progress. Researchers from these institutions have demonstrated a treatment that increases human insulin-producing beta cells in vivo for the first time, normalizing glucose levels in diabetic mice models. "It's very exciting to be close to seeing this novel treatment used in patients," said one of the researchers. "There is nothing like this available to patients right now."

New drug reverses diabetes in mice, boosting insulin-making cells by 700%

Nearly 13% of people with Parkinson’s disease in North America carry a Parkinson’s-associated genetic mutation, according to new data from the PD GENEration study. This suggests that genetic variants with a link to Parkinson’s are more common than previously thought. “The positivity rate and the high interest...

Parkinson’s mutations seen in nearly 13% of PD GENEration patients

The following is a summary of “DNA methylation landscape in pregnancy-induced hypertension: progress and challenges,” published in the July 2024 issue of Obstetrics and Gynecology by Deng et al. Gestational hypertension, particularly in the form of pre-eclampsia (PE), is a prevalent complication encountered during pregnancy, presenting substantial risks...

Exploring the DNA Methylation Landscape in Pregnancy-Induced Hypertension

ScienceAlert


A protein called interleukin 11 (IL-11) appears to play a crucial role in aging, with scientists extending the lifespans of mice by up to 25 percent simply by blocking the molecule's effects.



					
			

Led by researchers from the Duke-National University of Singapore (NUS) Medical School, the team behind the study used genetic engineering to turn off IL-11 production in a sample of mice, while injecting other mice with an anti-IL-11 drug.
Deaths from  cancer and tumorous growths were reduced in both groups, while health conditions related to the effects of aging – including chronic inflammation and poor metabolism – were also less...

Blocking One Protein Extends Lifespan in Mice by Up to 25%, Study Shows

The US Sun

A SINGLE-dose nasal spray treatment could 'wash away' build ups of toxic proteins associated with Alzheimer’s disease from brain cells and improve memory, scientists say. The study - performed on mice - paves the way for new treatments against Alzheimer's and dementia, researchers at the University of Texas Medical Branch said.

Single-dose nasal spray ‘washes the brain’ of toxic Alzheimer’s proteins – paving the way for breakthrough treatment

Muscle-on-chip systems are three-dimensional human muscle cell bundles cultured on collagen scaffolds. A Stanford University research team sent some of these systems to the International Space Station to study the muscle atrophy commonly observed in astronauts. It turns out that space triggers processes in human muscles that eerily resemble something...

Human muscle cells come back from space, look aged

Hard palate cancer is a rare oral cancer that forms on the roof of your mouth. While the exact cause may be unclear, some of the most common risk factors include tobacco and alcohol use. This form of cancer often appears as a bump or sore in your mouth that...

What to Know About Hard Palate Cancer

Strokes are caused by limited blood flow to the brain. Described as a cardiovascular disease, strokes result from a clogged or blocked blood vessel that leads to a lack of oxygen. Around 800,000 individuals have a stroke each year in the United States. The most common type of stroke is referred to as ischemic, which occurs when blood is occluded from a clot or narrow blood vessel. If the brain has low blood exposure, it limits the oxygen and nutrients the brain needs. As a result, brain cells begin to die, and a stroke occurs.

Strokes Have a Lasting Effect on Immune Cells

South Carolina State

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Colleton County, SC

Explore Beaufort SC

Some beachgoers were in for a surprise this week when a bizarre looking prehistoric fish washed ashore in Colleton County along Edisto Beach at Edisto Beach State Park. It turned out to be an atlantic sturgeon.

Rare Atlantic sturgeon washes ashore on South Carolina beach

A recent study published in the Journal of Psychiatric Research has unveiled disruptions in the brain connectivity of males with cocaine use disorder. This study found that male individuals with cocaine use disorder exhibit increased and more persistent brain connectivity in specific states, particularly within the default mode network, cognitive control network, and sensorimotor network. This heightened connectivity is linked to greater impulsivity and borderline personality traits, suggesting disruptions in self-regulation and emotional processing.

Increased brain connectivity in male cocaine users revealed by recent neuroimaging study

Denver, CO

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David Heitz

In addition to collecting more than 8,000 used needles in the past year from Denver drug users, the Harm Reduction Action Center passed out 10,000 meth pipes and “snort kits,” according to a newsletter sent to its supporters Thursday. They also connected about 1,700 people to medical, mental health and substance abuse treatment.

Denver group hands out 10K meth pipes, ‘snort kits,’ connects 1,700 to treatment annually

The brain undergoes significant development during childhood, and trauma can impact this development. Traumatic experiences in childhood can have neurological impacts, altering the functioning of the brain. Understanding how trauma impacts the brain can help clinicians better understand how and why symptoms present. A recent study published in Biological Psychiatry:...

How Childhood Trauma Can Impact the Brain

Colorado State

A bill quietly introduced this spring in the Colorado legislature to decriminalize the possession of drug paraphernalia obtained by harm reductionists has become law. As low-key as the legislation was introduced, the bill was signed into law without fanfare June 6. It garnered little to no media attention.

Colorado legalizes needles, pipes for meth and crack if obtained by harm reduction group

New York Post

Is there a sweet new solution to the bitter luck of baldness?

Scientists say they may have accidentally discovered a revolutionary cure for male pattern baldness, a genetic condition that affects up to half of men and a quarter of women by 50.



A research team from the University of Sheffield in England and COMSATS University in Pakistan stumbled upon this finding while studying how naturally-occurring deoxyribose sugar could heal wounds. 

Researchers were applying the sugar to the wounds of lab mice when they noticed that the fur around the lesions regrew rapidly. 

Suicidal thoughts spiked after deaths of Robin Williams, Kate...

A breakthrough for baldness? Sugar gel stimulates hair regrowth

For the first time, astronomers have captured an image of a neutron star emitting a ‘garden sprinkler-like’ S-shaped jet in the binary system Circinus X-1, located over 30,000 light-years away. This phenomenon, similar to precession observed in black holes, illustrates the jet’s direction change due to the gravitational...

First-Ever Sighting: Neutron Star’s Bizarre “Garden Sprinkler” Jet Captured

NewsBreak

Revolutionary DNA Nanotech Boosts Mass Cytometry by 500-Fold

ACE, a groundbreaking DNA-powered signal amplification technology, significantly enhances the sensitivity of mass cytometry, providing new insights into various biological and pathological processes. Since the 1950s,...

Revolutionary DNA Nanotech Boosts Mass Cytometry by 500-Fold

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