NCCN guidelines have been updated to recommend imetelstat to treat symptomatic anemia in patients with lower-risk myelodysplastic syndromes. The National Comprehensive Cancer Network (NCCN) has updated its clinical practice guidelines in oncology to now recommend imetelstat (Rytelo) as a Category 1 and 2A treatment for symptomatic anemia in patients with lower-risk myelodysplastic syndromes (MDS).1.

Updated NCCN Guidelines Recommend Imetelstat to Treat Anemia in Lower-Risk MDS

Approval marks the first time an immuno-oncology regimen has demonstrated a survival benefit for all adults with primary advanced or recurrent endometrial cancer, company says. The FDA has approved an expanded indication for GSK’s Jemperli (dostarlimab) to include treatment of all adults with primary advanced or recurrent endometrial cancer. According...

FDA Expands Approval of GSK’s Jemperli in Combination with Chemotherapy for Adults with Primary Advanced or Recurrent Endometrial Cancer

Miami, FL

Interventions, such as speech therapy, after receiving radioactive iodine treatment for thyroid cancer may help manage quality of life. After receiving radioactive iodine treatment for thyroid cancer, it’s important for patients to utilize the resources that are available, such as fertility preservation and speech therapy, an expert told CURE®.

Managing Quality of Life After Iodine Treatment for Thyroid Cancer

Healthline

Anemia and hemolytic anemia are both conditions that result in too few red blood cells. Their causes are different, but they have similar symptoms. Learn more.

What’s the Difference Between Anemia and Hemolytic Anemia?

Warm hemolytic anemia is a rare condition that affects your red blood cells. It causes anemia-like symptoms, such as fatigue, jaundice, and paleness. In warm hemolytic anemia, the destruction of red blood cells happens at body temperature. This isn’t always the case with other types of hemolytic anemias. The...

What to Know About Warm Hemolytic Anemia

A range of conditions, including alcohol or medication overuse, nonalcoholic fatty liver disease (NAFLD), and chronic infections, can damage your liver. However, the early signs of liver damage are subtle, and the initial stages of liver disease are "silent," or asymptomatic. By the time you recognize symptoms, your liver is already significantly damaged.

Signs of Liver Damage and Ways to Tell

Ferritin cutoffs of 30 and 45 ng/mL notably increase the rate of iron deficiency diagnoses. Guideline-recommended cutoffs for serum ferritin were linked to the incidence of iron deficiency diagnoses in primary care, according to a recent retrospective cohort study in JAMA Network Open.1. Across more than 255,000 adult primary care...

Ferritin Cutoff Choice Linked to Rates of Iron Deficiency Diagnosis

Health

Medically reviewed by Gagandeep Brar, MDMedically reviewed by Gagandeep Brar, MDThe red cell distribution width (RDW) blood test measures the differences in the volume and size of your red blood cells. Red blood cells help carry oxygen from the lungs to other parts of your body. Changes in the size of your red blood cells often represent a sign of an underlying medical condition, such as anemia (a reduced number of red blood cells or hemoglobin).Your healthcare provider may recommend an RDW test if they suspect you have an underlying condition. A high RDW means there is significant variation in...

What Do Your Red Cell Distribution Width (RDW) Blood Test Results Mean?

Research suggests that sickle cell anemia may offer some protection against HIV and may also slow HIV progression.

Can Sickle Cell Anemia Protect Against HIV?

Everyday Health

Hypoglycemia symptoms include having anxiety, emotional instability, dizziness, and lightheadedness. Here's a list with more signs to watch for.

10 Warning Signs of Low Blood Sugar

Among patients with fibromyalgia, there was a moderate negative correlation between vitamin D and physical functioning as well as between magnesium and stiffness. An exploratory study evaluating the link between specific micronutrients and the symptoms of fibromyalgia revealed vitamin D and magnesium played a role in physical function and stiffness among patients.1.

Vitamin D, Magnesium Deficiency Linked to Worse Fibromyalgia Symptoms

Medically reviewed by Rafle Fernandez, MDMedically reviewed by Rafle Fernandez, MDAn enlarged heart (also known as cardiomegaly) isn't a condition on its own but is often an underlying sign of heart problems. Several conditions like coronary artery disease, high blood pressure, and kidney disease can cause an enlarged heart.Some people with an enlarged heart don't experience symptoms at all, but others may experience symptoms like trouble breathing, a racing heartbeat, and fluid build-up—all of which tend to worsen with physical exertion.  
      What Size Should Your Heart Be?Typically, your heart is about the size...

Signs and Symptoms of an Enlarged Heart (Cardiomegaly)

Anemia is common in high-risk PCI and is independently associated with major adverse cardiovascular events and major bleeding risk. Baseline anemia is frequently identified in patients undergoing Impella-supported high-risk percutaneous coronary intervention (HRPCI), according to the results of a recent post hoc analysis of the PROTECT III study.1. The presence...

Anemia Linked to Adverse Outcomes After Percutaneous Coronary Intervention

A recent post hoc analysis published in PLOS One has revealed that pegcetacoplan may significantly improve hematologic outcomes and reduce fatigue in patients with paroxysmal nocturnal hemoglobinuria (PNH) who experience mild to moderate anemia. The study has demonstrated that treatment with pegcetacoplan, a complement component 3-targeted therapy, led to increases...

Patients With PNH and Anemia May Benefit From Pegcetacoplan Therapy

The FINEARTS-HF study, which compared Kerendia to a placebo when added to standard therapy, met its primary endpoint by reducing cardiovascular death and total heart failure events. Results from the Phase III FINEARTS-HF study found that Bayer’s Kerendia (finerenone) demonstrated significant efficacy in treating heart failure patients with a left...

Kerendia Demonstrates Significant Efficacy Treating Heart Failure with Left Ventricular Ejection Fraction of 40% or More

A physical therapist offers tips and exercises that can help patients with cancer who experiencing difficulty walking from either the disease or its treatments. Patients with cancer can experience difficulty walking for many reasons, from chemotherapy-induced neuropathy (pain and tingling in hands and feet) to fatigue, weakness and muscle pain.

Combatting Difficulty Walking During Cancer Treatments

There is no single test to diagnose Sjögren disease. Doctors will carry out a range of tests, such as blood, eye, and salivary gland tests, to look for signs of the disorder and rule out other conditions. Sjögren disease is an autoimmune disorder that causes dry eyes and mouth....

How do doctors diagnose Sjögren disease?

Researchers found that adults with overweight or obesity lost more weight with tirzepatide than semaglutide in a head-to-head comparison of the medications using electronic medical records data. Results showed that a weight loss of 15% or higher was achieved by 42.3% of the tirzepatide group vs. 18.1% of the semaglutide...

Top in endocrinology: Tirzepatide vs. semaglutide; FDA rejects icodec for diabetes

Kentucky State

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Northern Kentucky Tribune

Kentucky’s Community Actions Partnerships have announced the starts date for the Low-Income Home Energy Assistance Program (LIHEAP) Summer Subsidy, aimed at helping Kentucky households offset summer cooling costs.

LIHEAP Summer Subsidy program to help with summer cooling costs to begin enrollment July 16

Study shows patients 80 years and older with atrial fibrillation treated with a lower dose of edoxaban experienced fewer major gastrointestinal bleeding events for each additional ischemic stroke. Patients aged 80 years and above with atrial fibrillation (AF) may gain a benefit from treatment with lower-dose anticoagulants regardless of existing...

Phase III Trial Shows Older Patients with Atrial Fibrillation May Benefit From Lower-Dose Anticoagulants

NewsBreak

NCCN Recommends Rytelo for Anemia in Patients With MDS

The National Comprehensive Cancer Network now recommends Rytelo for patients with myelodysplastic syndrome who require blood transfusions. The National Comprehensive Cancer Network (NCCN) now recommends Rytelo...

NCCN Recommends Rytelo for Anemia in Patients With MDS

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