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Before tuning into Sunday's Bills vs. Cardinals game, you need to see the NFL picks from SportsLine's advanced computer model . The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 1 of the 2024 NFL season on an incredible 181-129 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 35-21 roll on top-rated NFL picks since Week 7 of 2022.
For Bills vs. Cardinals, the model is picking Buffalo to cover the 6.5-point spread. Buffalo has covered the spread in three of its last four home-opening games, while Arizona was a more unpredictable 4-4 ATS on the road in 2023.
There are some early-season questions regarding the Bills offense since wide receiver Stefon Diggs is no longer on the team. At the same time, Arizona's defense ranked 25th last season and is projected to be one of the worst in the league in 2024. Even if Allen and the offense are still trying to create chemistry, the model is leaning heavily on Buffalo to cover the spread at home on Sunday. You may be able to stream the game here .
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