NFL football pool, pick'em, office pool, confidence picks: Back the Chargers in Week 2, 2024

The New Orleans Saints and Dallas Cowboys had two of the most dominant victories in the NFL during Week 1. Now, they'll go head-to-head in a crucial Week 2 NFC matchup. The Saints smashed the Panthers, 47-10, last week, while the Cowboys downed the Browns, 33-17. The Saints will head to Dallas with a chance to prove they deserve to be considered a contender in the NFC, but who should you back with your Week 2 NFL office pool picks?

Meanwhile, in a critical AFC matchup that has become commonplace in recent years, Patrick Mahomes and Joe Burrow will go head-to-head as the Chiefs host the Bengals on Sunday. Who should you back with your NFL confidence pool picks and how should you be handling every game on the Week 2 NFL schedule in your NFL pick'em pools? Before you make your NFL predictions, you need to see the Week 2 NFL football pool picks from SportsLine's proven computer model .

Get football picks for every game from a proven NFL model

We'll give you one team to consider backing during Week 2. SportsLine's advanced computer model, which simulates every NFL game 10,000 times, is predicting the Los Angeles Chargers (-6.5) win comfortably on the road against the Carolina Panthers on Sunday.

New Chargers head coach Jim Harbaugh has experienced success at every stop and, if last week is any indicator, his team is quickly finding its identity. In a 22-10 win over the Raiders, the Chargers rushed for 176 yards and won the turnover battle 3-0. J.K. Dobbins carried the ball 10 times for 135 yards and a touchdown and now he'll take on a Panthers run defense that looked porous in Week 1.

Carolina gave up 180 rushing yards in a 47-10 loss to the Saints. It was the most yards the Panthers have given up on the ground since Week 9 of 2022 when they gave up 241 rushing yards to the Bengals. The model is expecting Harbaugh's squad to dominate the line of scrimmage once again, predicting a 30-16 win on average with the Chargers winning in nearly 80% of simulations. See all of SportsLine's Week 2 NFL predictions here .

How to make Week 2 NFL office pool picks

The model also made the call on every other Week 2 NFL game and has strong picks for potentially close NFL matchups like Jaguars vs. Browns, Cowboys vs. Saints and Ravens vs. Raiders. It's also calling for two Super Bowl contenders to go down hard. You can only see all of the model's NFL pool picks here .

So who should you pick in every Week 2 NFL game, and which Super Bowl contenders should you avoid? Visit SportsLine now to get optimal NFL office pool picks, all from a proven computer model that has returned well over $7,000 since its inception , and find out.