General Hospital promises fans an Autumn to remember

Isaiah will be in the middle of the Port Charles dramaPhoto bySoap Dirt YouTube screenshot

What happens with Holly and Lucky?

Virginia General Hospital fans, spoilers have promised an Autumn to remember in Port Charles, and things are already lining up. Lucky Spencer (Jonathan Jackson) is trying to escape and work a deal with Holly Sutton (Emma Samms).

Lucky's friend, Dr. Isaiah Gannon (Sawandi Wilson), has already mentioned his name to Liz Webber (Rebecca Herbst), and spoilers tease Isaiah might be a romantic interest for Jordan Ashford ( Tanisha Harper).

Which romances will take off and will there be a murder?

Rumors are flying that Liz and Lucky might reunite, but Ric Lansing (Rick Hearst) currently seems to be romancing his ex. Sam McCall ( Kelly Monaco) is set to die this fall, and General Hospital predictions suggest that a deranged Kristina Corinthos (Kate Mansi) might murder her sister.

The drama surrounding Kristina, Sonny Corinthos (Maurice Benard), Alexis Davis (Nancy Lee Grahn), and Jagger Cate's death has multiple twists and turns, plus Kristina wants Ava Jerome (Maura West) dead.

Could Sam die trying to stop her sister from killing Ava? Stay tuned, Virginia fans. It sounds like Autumn will be wild in Port Charles.