NFL odds, Vegas lines, picks, spreads, game predictions: Model backing Ravens, Buccaneers in Week 2, 2024

The Week 2 NFL schedule is loaded with NFL matchups that oddsmakers predict will be hard-fought battles. Of the 16 NFL games in Week 2, only one features a spread higher than seven points, with the Ravens favored by 8.5 over the Raiders according to the latest Week 2 NFL odds from the SportsLine consensus. There are eight games in the Week 2 NFL lines featuring NFL spreads of fewer than five points, which could make your Week 2 NFL picks a challenge. One of the closest NFL Vegas lines of the week comes in a NFC East division rivalry, with the Washington Commanders favored by two against the New York Giants at home, but which NFL bets should you make? What about NFL prop bets, NFL touchdown bets, and NFL parlay picks? All of the Week 2 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 2 NFL picks now .

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on A-rated NFL picks since its inception. The model enters Week 2 of the 2024 NFL season on an incredible 184-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 38-22 roll on A-rated NFL picks since Week 7 of the 2022 NFL season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 2 NFL odds and NFL betting lines on the spread , money line , and over-under , and locked in picks for every NFL matchup. Head here to see every pick .

Top Week 2 NFL predictions

We can tell you one of the model's strongest Week 2 NFL picks is that the Ravens (-8.5, 41.5) cover at home versus the Raiders. Despite suffering a 27-20 setback in the season opener, the Ravens were effective on offense, especially quarterback Lamar Jackson.

The reigning NFL MVP threw for 273 yards and a touchdown, while also rushing for 122 yards on 16 carries. Running back Derrick Henry racked up 43 rushing yards and a touchdown in his Ravens debut and now Baltimore's dynamic rushing attack will take on a Raiders defense that gave up more than 175 rushing yards in Week 1. The Ravens are 5-2 against the spread in their past seven games when playing as the favorite, while the Raiders are 1-7 ATS in their last eight games on the road against Baltimore. That's a big reason why the model has Baltimore (-9.5) winning by double digits and covering well over 50% of the time. See which other teams to pick here .

Another one of its Week 2 NFL predictions: the Buccaneers (+7.5, 51) cover on the road versus the Lions . Tampa Bay had the No. 2 scoring offense last week in its 37-20 win over the Commanders behind a dominant performance from Baker Mayfield. The 29-year-old quarterback completed 24 of 30 passes for 289 yards and four touchdowns last week. Mayfield had a resurgence last season, setting career-highs in completion percentage (64.3%), passing yards (4,044) and touchdowns (28) last year in his sixth NFL season. After some concerns about losing his offensive coordinator with Dave Canales becoming the Panthers head coach, Mayfield showed Week 1 he still has the tools to succeed.

Tampa Bay went 8-2 ATS on the road last season and were underdogs in nine of those 10 contests. The Buccaneers' offense has strong continuity back from last season and that showed with Mike Evans having five receptions for 61 yards and two touchdowns and Chris Godwin recording eight receptions for 83 yards and a score last week. The Lions needed overtime last weekend to knock off the Rams, 26-20, and allowed 317 passing yards to Matthew Stafford. The model simulates the Buccaneers to cover almost 60% of the time. The Under (51) is also forecasted to hit in over 60% of simulations. See which other teams to pick here .

How to make Week 2 NFL picks

The model has also made the call on who wins and covers in every other game on the Week 2 NFL schedule and just revealed four coveted A-rated picks against the spread. You can only get every pick for every game at SportsLine .

So what NFL picks can you make with confidence, and which four A-rated NFL against-the-spread picks should you lock in now? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $7,000 , and find out.

Week 2 NFL betting odds, lines, spreads

Get Week 2 NFL picks at SportsLine

Thursday, Sept. 12

Bills at Dolphins (-2.5, 48.5)

Sunday, Sept. 15

Raiders at Ravens (-8.5, 41.5)

Chargers at Panthers (+6, 39)

Saints at Cowboys (-6.5, 46.5)

Buccaneers at Lions (-7.5, 51)

Colts at Packers (+3, 41)

Browns at Jaguars (-3, 41.5)

49ers at Vikings (+5.5, 45.5)

Seahawks at Patriots (+3.5, 38.5)

Jets at Titans (+3.5, 40.5)

Giants at Commanders (-1.5, 43)

Rams at Cardinals (-1, 48.5)

Bengals at Chiefs (-5.5, 47.5)

Steelers at Broncos (+2.5, 36.5)

Bears at Texans (-6, 45.5)

Monday, Sept. 16

Falcons at Eagles (-6.5, 47)