Amid things like a missing gun and grieving a baby, fans of General Hospital have bigger concerns: Lois’ new voice. Since her 1993 arrival to Port Charles, Lois (Rena Sofer) has been known for two things: extravagant nails and a big Brooklyn accent. Her late 2023 return offered long-time GH fans nostalgia when she came back with long colorful nails and that familiar accent echoing through the Quartermaine Mansion.