NFL odds, Vegas lines, picks, spreads, game predictions: Model high on Browns, Bengals in Week 3, 2024

Cowboys vs. Ravens on Sunday will pit last year's No. 1 ranked-scoring offense against the top-ranked scoring defense. The Ravens are 1-point road favorites in one of the slimmest Week 3 NFL spreads, while the largest comes in Bengals vs. Commanders game on Monday Night Football. Cincinnati is favored by 7.5 points in the Week 3 NFL odds, as two preseason Super Bowl contenders in the Ravens and Bengals look to avoid 0-3 holes.

The only team in the AFC North with a winning record, the Steelers, are 1.5-point home favorites over the fellow undefeated Chargers. After winning in Carolina on Sunday, L.A. is taking the rare step of not traveling back home in between games and is staying on the East Coast. Should this strategy affect your Week 3 NFL best bets for this game? All of the Week 3 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 3 NFL picks now .

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on A-rated NFL picks since its inception. The model enters Week 3 of the 2024 NFL season on an incredible 187-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 41-22 roll on A-rated NFL picks since Week 7 of the 2022 NFL season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 3 NFL odds and NFL betting lines on the spread , money line , and over-under , and locked in picks for every NFL matchup. Head here to see every pick .

Top Week 3 NFL predictions

We can tell you one of the model's strongest Week 3 NFL picks is that the Browns (-6.5, 38.5) cover the spread versus the Giants . Cleveland had a dominant defensive effort in its Sunday win over Jacksonville, holding Trevor Lawrence (46.67 CMP%) under a 50% completion percentage for just the fourth time in his pro career. That defense should have even more fun facing Daniel Jones, whose 54.3% CMP% ranks 28th out of 31 qualified QBs this season.

This game will take place in front of the Dawg Pound, and the Browns are unparalleled when it comes to recent spread success at home. They are 8-2 at home against the spread since the start of last season, which is the best record in the league, and their 6-1 ATS record as a home favorite over that span is also the best mark in the NFL. Jones has lost four straight road starts, failing to throw a TD pass in three of those, and the Giants are 1-8 overall over their last nine away games. With that, the Browns (-6.5) are forecasted to cover in nearly 60% of simulations. See which other teams to pick here .

Another one of its Week 3 NFL predictions: the Bengals (-7.5, 48.5) cover versus the Commanders. Now that Weeks 1 and 2 are over with, the real Bengals will show up as they simply don't know how to start the season off right. Burrow is just 1-9 in his career over the first two weeks of seasons, but he's 33-17-1 thereafter, including the postseason. Despite Sunday's loss to the Chiefs , Cincinnati did cover, and it is nearly undefeated versus the spread in recent matchups with NFC teams. Over their last 10 non-conference games, the Bengals have lost just once ATS.

Washington has serious issues with the passing game, both on offense and on defense. Daniels has yet to throw a single touchdown pass, and no Commanders player has even 100 receiving yards on the season. On the other side of the ball, Washington has allowed the most passing touchdowns (six), which is simply a continuation of last season, as the team also gave up the most passing TDs in 2023. Burrow is coming off a two-TD, zero-INT game in a hostile environment in Kansas City, so he should dice up the Commanders at home. The model has Cincinnati (-7.5) covering well over 50% of the time, with the Over (48.5) hitting in well over 60% of simulations. See which other teams to pick here .

How to make Week 3 NFL picks

The model has also made the call on who wins and covers in every other game on the Week 3 NFL schedule and just revealed three must-see underdogs who win outright, potentially giving you a huge payday. You can only get every pick for every game at SportsLine .

So what NFL picks can you make with confidence, and which three must-see underdogs should you lock in now? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $7,000 , and find out.

Week 3 NFL betting odds, lines, spreads

Get Week 3 NFL picks at SportsLine

Thursday, Sept. 19

Patriots at Jets (-6.5, 37.5)

Sunday, Sept. 22

Giants at Browns (-6.5, 38.5)

Bears at Colts (-1.5, 42.5)

Texans at Vikings (+2.5, 45.5)

Eagles at Saints (-1.5, 49.5)

Chargers at Steelers (-2, 35.5)

Broncos at Buccaneers (-6.5, 39.5)

Packers at Titans (-2.5, 36.5)

Panthers at Raiders (-5.5, 40.5)

Dolphins at Seahawks (-5.5, 41)

Lions at Cardinals (+3, 51.5)

Ravens at Cowboys (+1, 49)

49ers at Rams (+7.5, 43.5)

Chiefs at Falcons (+4.5, 46.5)

Monday, Sept. 23

Jaguars at Bills (-5.5, 45.5)

Commanders at Bengals (-8, 48.5)