<body><div><figure><img src="https://img.particlenews.com/image.php?type=thumbnail_580x000&amp;url=0S04Hx_0vZnDOtV00" alt="https://img.particlenews.com/image.php?url=0S04Hx_0vZnDOtV00" width="1280" height="853" ><figcaption>Jacksonville Jaguars vs. Buffalo Bills: This NFL prediction is based on thousands of data-driven simulations of the game. AP</figcaption></figure><p>The Buffalo Bills will take on the Jacksonville Jaguars in Week 3 of the NFL season at Highmark Stadium on Monday. Kickoff is at 7:30 p.m. ET. While Buffalo, led by Josh Allen and their red-hot offense take advantage of a long week to prepare for an 0-2 Jaguars team that is desperate to find its footing, the data analysts at <a href="http://dimers.com/">Dimers.com</a> have simulated the Bills-Jaguars matchup 10,000 times, then compared the results to current NFL betting odds to inform the data-driven betting preview below.</p><p>This preview includes Dimers’ best bets and predicted scoreline for the Buffalo Bills vs. Jacksonville Jaguars. To unlock Dimers’ full suite of data-driven betting insights, which includes daily props, trends, and parlays, <a href="https://www.dimers.com/subscription?utm_source=advance-local&amp;utm_medium=affiliate&amp;utm_campaign=pro&amp;utm_content=article">sign up for Dimers Pro with promo code SYRACUSE10</a>, which will save you 10% off your first subscription payment.</p><p>If you’re a local football fan in Pennsylvania using this data to bet on the Bills or Jaguars, you can claim huge betting bonuses with the <a href="https://www.syracuse.com/betting/2024/09/fanduel-promo-code-for-mnf-unlocks-200-in-bonus-bets-plus-125-nfl-sunday-ticket-discount.html">new FanDuel promo code for NFL Sunday Ticket</a>, <a href="https://www.syracuse.com/betting/2024/09/draftkings-promo-code-secure-250-bonus-bets-for-nfl-mlb-and-wnba-action.html">this upgraded DraftKings promo</a> that <a href="https://www.syracuse.com/betting/2024/09/how-betting-on-ufc-306-tonight-unlocks-nfl-sunday-ticket-nfl-premium-and-bonus-bets-for-sunday-football.html">now includes an NFL RedZone free trial</a>, and <a href="https://www.syracuse.com/betting/2024/09/extended-bet365-bonus-code-dimers-secure-1k-betting-deal-for-monday-night-football-mlb-and-wnba-this-week.html">the exclusive Bet365 bonus code “DIMERS”.</a></p><h2>Jaguars vs. Bills betting preview</h2><p>Explore the interactive widget below to view the current spread, total, and moneyline odds and probabilities for the Jaguars-Bills matchup at Highmark Stadium.</p><p>This prediction and best bet for Monday’s NFL matchup between the Jaguars and Bills is from <a href="https://www.dimers.com/">Dimers.com</a>, a reliable source for sports betting predictions.</p><p>Check out all the important details on tonight’s game, as well as the best odds sourced from the top sportsbooks in the country.</p><h2>Game details</h2><p>The key information you need before the Jaguars vs. Bills NFL game.</p><ul><li><b>Teams:</b> <a href="https://www.jaguars.com/">Jacksonville Jaguars</a> vs. <a href="https://www.buffalobills.com/">Buffalo Bills</a></li><li><b>Date:</b> Monday, September 23, 2024</li><li><b>Kickoff:</b> 7:30 p.m. ET</li><li><b>Location:</b> Highmark Stadium</li></ul><h2>Odds</h2><p>The latest and best odds for the NFL contest between the Jaguars and Bills.</p><ul><li>Jaguars +5.5 (-105), Bills -5.5 (-110)</li><li><b>Moneyline:</b> Jaguars +220, Bills -250</li><li><b>Total:</b> Over/Under 46.5 (-105/-115)</li></ul><p>The odds and lines presented in this article are the best available from selected <a href="https://www.dimers.com/best-books">sports betting sites</a> at the time of publication and are subject to change.</p><h2>Expert prediction: Jaguars vs. Bills</h2><p>Utilizing trusted data analysis and machine learning, <a href="https://www.dimers.com/">Dimers</a> has executed 10,000 simulations of Monday’s <a href="https://www.dimers.com/bet-hub/nfl/schedule/2024_3_buf_jax">Jaguars vs. Bills</a> matchup.</p><p>According to Dimers’ popular predictive analytics model, the <b>Bills are more likely to defeat the Jaguars</b> at Highmark Stadium. This prediction is based on the model giving the Bills a 70% chance of winning the game.</p><p>Furthermore, Dimers predicts that the bookmakers have got it right and the Jaguars and Bills each have a 50% chance of covering the spread, while the 46.5-point over/under has a 52% chance of staying under.</p><p>These predictions and probabilities are accurate at the time of publication but are subject to potential changes.</p><h2>Jaguars vs. Bills best bet</h2><p>Our top pick for the Jaguars vs. Bills Week 3 NFL game is to bet on the <b>Jaguars moneyline (+220)</b>.</p><p>This betting advice is based on comprehensive modeling and valuable betting intelligence, designed to bring you the best possible plays.</p><p>While the Bills are more likely to win the game, according to Dimers, taking the Jaguars moneyline is the best option because of the edge identified when comparing Dimers’ data-driven probabilities to the betting odds.</p><h2>Score prediction for Jaguars vs. Bills</h2><p>Dimers’ predicted final score for the Jacksonville vs. Buffalo game on Monday has the Bills winning 25-20.</p><p>This expert prediction is based on each team’s average score following 10,000 game simulations, offering a glimpse into the potential outcome.</p><h2>NFL Week 3: Jaguars vs. Bills</h2><p>Get ready for Monday’s game between the Jaguars and Bills in Week 3 of the <a href="https://go.skimresources.com/?id=126006X1587360&amp;xs=1&amp;url=https%3A%2F%2Fwww.nfl.com%2F">NFL</a> season at Highmark Stadium, which is scheduled to start at 7:30 p.m. ET. To add an extra level of excitement, consider exploring <a href="https://www.syracuse.com/betting/dimers-pro/">Dimers Pro</a>, where you can get the <a href="https://www.dimers.com/parlay-picker">best parlay bets today</a>.</p><p>We emphasize that all of the <a href="https://www.dimers.com/bet-hub/nfl/schedule">NFL predictions</a> and <a href="https://www.dimers.com/best-bets/nfl/">NFL best bets</a> in this preview are based on 10,000 data-driven simulations of the Jaguars vs. Bills game, and they are correct at the time of publishing. They aim to assist you make better decisions when placing bets at online <a href="https://www.syracuse.com/betting/sportsbooks">sportsbooks</a>.</p><p>Please note that when engaging in online betting, it is important to exercise responsible gambling practices and consult trustworthy sources for accurate and up-to-date information.</p></div></body>

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NFL Week 3 early prediction: Buffalo Bills maintain momentum, stampede Jacksonville Jaguars on Monday Night Football

The Buffalo Bills will take on the Jacksonville Jaguars in Week 3 of the NFL season at Highmark Stadium on Monday. Kickoff is at 7:30 p.m. ET. While Buffalo, led by Josh Allen and their red-hot offense take advantage of a long week to prepare for an 0-2 Jaguars team that is desperate to find its footing, the data analysts at Dimers.com have simulated the Bills-Jaguars matchup 10,000 times, then compared the results to current NFL betting odds to inform the data-driven betting preview below.

NFL Week 3 early prediction: Buffalo Bills maintain momentum, stampede Jacksonville Jaguars on Monday Night Football

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