Sunday Night Football prediction, odds, line, spread: Ravens vs. Bills picks by Baltimore expert on 48-22 run

The Buffalo Bills face off with the Baltimore Ravens in a Week 4 matchup on Sunday Night Football from Baltimore's M&T Bank Stadium. Baltimore coach John Harbaugh will look to improve on his 161-101 (.615) career record, while Buffalo coach Sean McDermott is 76-41 (.650). The Bills (3-0), who have won the last two meetings with Baltimore, including one postseason matchup, have won nine of their last 14 conference matchups since the beginning of last season. The Ravens (1-2), who are 6-4 at home since the start of 2023, are 8-6 in the conference since last September.

Kickoff in Baltimore is set for 8:20 p.m. ET. Baltimore is a 2.5-point favorite in the latest Ravens vs. Bills odds from the SportsLine Consensus, while the over/under for total points scored is 46.5. Before you make any Bills vs. Ravens bets or predictions, make sure you check out what SportsLine NFL expert Mike Tierney has to say, considering his mastery of picks involving the Ravens .

A veteran sportswriter whose work appears periodically in the New York Times and Los Angeles Times, Tierney has covered the NFL for decades and reported from seven Super Bowls. Tierney is 154-124-9 in the NFL the past two seasons, returning $1,586 to $100 players. In addition, he is an amazing 48-22-2 on his last 72 NFL picks in games involving the Baltimore Ravens, returning a whopping $2,362. Anyone who has followed him is way up.

Now, Tierney has zoned in on Bills vs. Ravens . You can head to SportsLine to see his picks . Here are the NFL odds and NFL betting lines on the spread , money line , and over-under for Bills vs. Ravens:

• Ravens vs. Bills spread: Baltimore -2.5
• Ravens vs. Bills over/under: 46.5 points
• Ravens vs. Bills money line: Buffalo +119, Baltimore -141
• BUF: Bills have hit the second-quarter game total over in 14 of their last 19 games (+9.30 units)
• BAL: Ravens have covered the first-half spread in 16 of their last 22 games (+9.30 units)
• Ravens vs. Bills picks: See picks at SportsLine

Why the Ravens can cover

Quarterback Lamar Jackson is off to another solid start to the season, completing 59 of 90 passes (65.6%) for 702 yards and three touchdowns. The reigning NFL MVP has been intercepted just once and has a rating of 95.7. He is second on the team in rushing, carrying 35 times for 254 yards (7.3 average) and one touchdown. He also has one explosive play of 25 yards and has converted 14 first downs.

Linebacker Kyle Van Noy is among the defensive leaders. He has six solo tackles and has four sacks for 31 yards with five tackles for loss. He also has one pass breakup. The 12th-year veteran is in his second season with the Ravens. Last year he registered a career-high nine sacks and had two forced fumbles, 30 tackles, including 20 solo, with four pass breakups and one stuff. See who to back at SportsLine .

Why the Bills can cover

Quarterback Josh Allen completed 23 of 30 attempts (76.7%) for 263 yards and four touchdowns with no interceptions and a 142.1 rating last week. He also led the Bills with 44 rushing yards, the 11th game with four or more touchdown passes since 2020, and the most in the NFL during that span. Allen is the only quarterback in the NFL with no interceptions and a 100-plus rating in each of the first three weeks of the season. He totaled 283 yards (213 passing and 70 rushing) and two touchdowns (one passing and one rushing) in the last meeting with Baltimore. He is 6-1 in seven career starts on Sunday Night Football.

Running back James Cook had 87 yards from scrimmage (48 receiving and 39 rushing) and a rushing TD last week. Cook is one of four running backs with 85 or more scrimmage yards in each of the first three weeks of the season. He will also be looking for his third game in a row with a touchdown. For the season, Cook has rushed for a team-high 188 yards and three TDs. See who to back at SportsLine .

How to make Bills vs. Ravens picks

Tierney has analyzed Ravens vs. Bills from every possible angle and while we can tell you he's leaning Over the point total, he has also discovered a critical X-factor that has him jumping all over one side of the spread. Head to SportsLine to see what it is, and find out which team to back .

Who wins Bills vs. Ravens on Sunday Night Football, and which critical x-factor makes one side of the spread hit hard? Visit SportsLine now to see which side of the Bills vs. Ravens spread you need to jump on, all from the expert who is 48-22 on picks involving the Ravens , and find out.