Fantasy Football Week 6 Start 'Em & Sit 'Em Quarterbacks: Dak Prescott has top-five upside this week, and more

One quarterback who I struggle with ranking this week is Baker Mayfield . I consider him a No. 1 quarterback in all leagues, but this is a difficult matchup for him in Week 6 at New Orleans.

Mayfield failed to score at least 20.8 Fantasy points only once this season, which was Week 3 against Denver. Since then, he's scored at least 29.4 Fantasy points in consecutive games against the Eagles and Falcons , and I'm hopeful he can stay hot against the Saints .

But New Orleans has yet to allow a quarterback to score more than 15.2 Fantasy points, including matchups with Dak Prescott , Jalen Hurts , Kirk Cousins , and Patrick Mahomes . That's an impressive group of quarterbacks, and the Saints will make things uncomfortable for Mayfield in this matchup.

Now, Mayfield averaged 24.6 Fantasy points against the Saints in two games last season, and I hope he can stay in that range again. I have Mayfield ranked at No. 12 as of Wednesday morning, and this should be another 20-point outing for him despite the difficult opponent.

Here are the rest of the quarterbacks that I recommend starting in Week 6, as well as the ones to avoid. And make sure you check back later in the week for my sleepers column for an update on the Colts situation since we don't know the health of Anthony Richardson (oblique), which will impact the status of Joe Flacco .